Alka Seltzer Tablets Lab Report

Aspirin, Caffeine and Salicylamide were extracted from an over-the-counter pain reliever (BC Powder). These components were separated by manipulating their solubilities by adjusting the acidity and basicity of the solution. By doing this, the three components were forced into conjugate acid (or base) forms, causing selective solubility in either an aqueous or organic solvent. These layers were then separated by use of a separation funnel. Once separated, the components extracted were characterized by measuring the melting point and performing a TLC analysis. Also, the recovered aspirin from the first part of the experiment was recrystallized and compared to that of the

The goal of this experiment was to synthesize aspirin. In this experiment aspirin, also known as acetylsalicylic acid, was synthesized from salicylic acid and acetic anhydride. In the reaction the hydroxyl group on the benzene ring in salicylic acid reacted with acetic anhydride to form an ester functional group. This method of forming acetylsalicylic acid is an esterification reaction. Since this esterification reaction is not spontaneous, sulfuric acid was used as a catalyst to initiate the reaction. After the reaction was complete some unreacted acetic anhydride and salicylic acid was still be present in the solution as well as some sulfuric acid, aspirin, and acetic acid. Crystallization, which uses the principle of

The reaction you will be investigating is the reaction that occurs when an Alka-Seltzer tablet is placed into a given amount of water. Alka-Seltzer is an over-the-counter antacid and pain relief medication that is dissolved in water before it is ingested. Each tablet contains aspirin (acetylsalicylic acid), citric acid, and sodium bicarbonate. As the tablet dissolves in water, the bicarbonate ions in the tablet react with the hydrogen ions from the acids that are also contained in the tablet. The carbon dioxide gas produced by the reaction is what causes the bubbling that can be observed.

The goal of this lab was to determine the amount of grams of sodium bicarbonate (NaHCO3) required to produce enough CO2 gas to completely fill the lab and also how many Alka-Seltzer tablets that would equate to. This was done by collecting CO2 gas by inverting a buret and submerging it under water in order to calculate the volume of CO2 released from a fragment of Alka-Seltzer tablet. The main component of Alka-Seltzer is sodium bicarbonate, used to neutralize excess stomach acid during illness through the following reaction that generates CO2:

Pre-Lab: Analgesic drugs are known for reducing pain, while antiseptic drugs reduce symptoms such as fevers and swelling. However, some of these drugs can reduce both illnesses. To obtain a pure compound in these drugs, the scientist needs to separate the desired compound by taking advantage of the different physical and chemical properties. Such as; different boiling points, melting points and their solubility properties. To do this a chemist can also asses the differences between acidic and basic substances when they are added to water soluble mixtures. Within this current experiment I will asses the

Alka Seltzer is a medicine that acts as a pain reliever and an antacid. Antacids are used to help neutralize the acids in the stomach and help treat acid reflux, heartburn, indigestion, and gastritis. The tablets contain sodium bicarbonate (NaHCO3) and citric acid (C6H8O7). The sodium bicarbonate is a base that helps neutralize the acids in the stomach, mainly hydrochloric acid (HCl). It does this by the following reaction: Na3C3H5O7(aq) + 3HCl(aq) H3C3H5O7(aq) + 3NaCl(aq). When the tablets are dropped into the water, a reaction occurs in which water (H2O), sodium citrate (Na3C6H5O7), and carbon dioxide (CO2) are formed.

Alka Seltzer is a medical drug used for pain relief and used for relieving indigestion. For example, if you have a stomachache or some indigestion problems, Alka Seltzer may help neutralize the stomach acidity. Not only that, Alka Seltzer is also used for cleaning household items, such as vases or jewelry. Alka Seltzer contains citric acid and sodium bicarbonate, which makes it dissolve and release carbon dioxide gas when dropped in water. In this experiment, my lab partner, Rebecca, and I are trying to find a way to make Alka Seltzer dissolve faster in water. Rebecca and I both decide that if we increase the temperature of the water or make the water hotter, then the Alka Seltzer will dissolve faster because I know when salt and sugar dissolve in hot water, they dissolve faster. I predict that this same result would apply to this experiment.

The lab we did utilizes the varying acidity, polarity, and solubility of aspirin, acetaminophen, and caffeine to teach undergraduate organic chemistry students a variety of laboratory techniques. The purpose of this lab was to use the properties of the active components in Excedrin to learn and apply the techniques of acid-base extraction and Thin Layer Chromatography. Utilizing these techniques, we were able to separate the three components of Excedrin, confirm their identities, and check the purity of our products. The theory behind the acid-base extraction we conducted is to use the acidity level of each of the components of Excedrin to separate them without using the common separation method of temperature changes. Acid-base extraction is used to isolate compounds by using ionic salts like K2HPO4 and KOH to make the compound water soluble then adding an acid like HCl to protonate the compound and make our desired product precipitate out since it returns the component back to neutral.

Alone taking aspirin can only offer fever and pain relief but if in combination with sodium hydrogen carbonate and citric acid like in Alka Seltzer, it can also offer relief of heartburn, stomach aches and acid reflux. So if a person had more than 1 of those symptoms they wouldn’t have to take multiple medicines.

Within this experiment we were to analyze four difference analgesic drugs and compare them to different components to see which drug contained what. The components that were used for comparison are Acetylsalicylic acid (ASA), Acetaminophen (Ace), Ibuprofen (Ibu), and Caffeine (Caf). The components all have different levels of polarity. To determine the level of polarity before the experiment even starts can be done by looking at the functional groups. The structures can be found under objectives in the carbon copies with the visual representation of what will be said. After observing each structure and determining the functional groups it can be said that caffeine is the most polar out of all of them. This is because it has two carbonyl groups and four amine groups.

Ibuprofen and Acetaminophen are synthetic mixes created to treat a collection of agony conditions. Ibuprofen can be utilized as a torment executioner and lessens irritation. The historical backdrop of ibuprofen can be followed back to 400BC times when Hippocrates utilized the willow leaf tea as a torment reliever for ladies amid labor. In 1763 Revererend Edward Stone uses willow bark to treat rheumatic fever. It wasn't until 1823 when the dynamic fixing, salicin, is separated from willow. The dynamic fixing was likewise found in 1838 by Swiss and German analysts in meadowsweet bloom. French researchers in 1853 makes salicylic corrosive from salicin. In any case, they understood an annoyed stomach is an unanticipated symptom of ingesting salicylic

Antacids is a group of medicines which help to neutralise the acid content of your stomach (Patient Online). Many antiacid makers claim that there products are always the best to be used. Antacids can be used to treat: heartburn, indigestion and symptoms of acid reflux. Alka-seltzer is known for being a great painkiller that provides effective and fast relief of headaches and upset stomachs. There are many other brands that are similar to Alka-seltzer such as Tums & Rolaids. Tums are known to be America’s #1 Antacid brand, that goes to work instantly for fast heartburn relief (TUMs.com). Rolaids share some similarities from both Alka-seltzer and tums, with a slight difference in ingredients. During this experiment, the main focus is figuring

After completing a seven week experiment testing the potency of cetirizine in allergy pills, I felt obligated to inform a member of congress on the importance of knowing the true expiration data of pharmaceuticals.

Metabolic alkalosis is a primary increase in serum bicarbonate (HCO3-) concentration. This occurs as a consequence of a loss of H+ from the body or a gain in HCO3-. In its pure form, it manifests as alkalemia (pH >7.40). As a compensatory mechanism, metabolic alkalosis leads to alveolar hypoventilation with a rise in arterial carbon dioxide tension (PaCO2), which diminishes the change in pH that would otherwise occur.

Caffeine is the most consumed drug in the world and coffee is the second most traded commodity, next to oil. Origins of its use date back to the eleventh century. It is commonly known for being a stimulant: a substance that raises levels of physiological or nervous activity in the body. Caffeine is also a diuretic as it increases the activity of the cardiovascular system, which increases heart rate and blood pressure. Thus the renal system encounters a higher volume of blood to filter, resulting in waste output. However, recent research shows only high quantities of caffeine produced significantly more urine volume. Another misconception about caffeine is that it is dehydrating. In actuality, it only has a dehydrating effect when consumed in high quantities and when an individual is deprived of other fluids. Other ingredients in caffeinated foods and beverages, such as taurine, are responsible for dehydration.