Alzheimer's Disease Lab Report

The FDA recently has allowed two treatments to be used for Alzheimer patients. One of the treatments is a Partial Glutamate Antagonist, which is an important transmitter to the brain. It is said that Glutamate helps patients more than sugar pills do, however; it is said that too much

Some of the numerous antioxidants included in red wine are Anthocyanins, flavonols, catechins, flavonoids,resveratrol. “During the last two decades, several epidemiological studies have shown that moderate consumption of red wine may contribute to a reduction in the mortality rate due to cardiovascular diseases.” (El Rayess 3). This is completely contradictory to the argument that alcohol has no benefits, when in fact it can possibly reduce heart disease and cancers. This data further stresses the fact that the government should be more concerned with the health risks of cigarettes and tobacco because statistics support the idea that alcohol is relatively safer for

This study will investigate and test how some medications can smooth the progressive advance of the Alzheimer in patients with more than 70 years. Alzheimer which is a degenerative disease of the neuro system due to memory loss is still being very questionable and debated. As of today there is no cure, nor reversal for the disease. Many researchers are still studding and looking for therapies and medication that can stop or reverse the development of the disease. It is very important to prove that some medications can help to cope with the disease. In my study I will be able to demonstrate

Alzheimer’s disease affects the lives of over 5 million Americans today. The cost that it has placed on the U.S is a staggering $203 million dollars. Researchers have reported that those numbers are expected to triple by 2050. However draining that this disease may seem, the real question is whether there is a solution. To this day there is still no cure to stop or even slow down th progression of the brain disease but there are treatments that help cover the symptoms. While the majority of the people who suffer from Alzheimer is generally over the age of 65, about 200,000, of the estimated 5 million, are in the age range of 30-40.

Resveratrol (3,4 ',5-trihydroxystilbene) is a naturally occurring phytochemical present in red wine, grapes, berries, chocolate and peanuts. Clinically, resveratrol has exhibited significant antioxidant, anti-inflammatory, anti-viral, and anti-cancer properties. Although resveratrol was first isolated in 1940, it was not until the last decade that it was recognised for its potential therapeutic role in reducing the risk of neurodegeneration, and Alzheimer 's disease (AD) in particular. AD is the primary cause of progressive dementia. Resveratrol has demonstrated neuroprotective effects in several in vitro and in vivo models of AD. Apart from its potent antioxidant and anti-inflammatory roles, evidence suggests that resveratrol also facilitates non-amyloidogenic breakdown of the amyloid precursor protein (APP), and promotes removal of neurotoxic amyloid beta (Aβ) peptides, a critical step in preventing and slowing down AD pathology. Resveratrol also reduces damage to neuronal cells via a variety of additional mechanisms, most notably is the activation of NAD+-dependent histone deacetylases enzymes, termed sirtuins. However in spite of the considerable advances in clarifying the mechanism of action of resveratrol, it is unlikely to be effective as monotherapy in AD due to its poor bioavailability, biotransformation, and requisite synergism with other dietary factors. This review summarizes the relevance of resveratrol in the pathophysiology of AD. It also highlights

The early onset symptoms of dementia could be missed due to various reasons. Many people consult with their regular physician who may not know too much about dementia and its symptoms. A brief office visit is another factor; this short time does not give the patient and doctor enough time to connect to understand all the symptoms, duration, and review patient history. There are many other medical conditions that mimic dementia symptoms that make a proper diagnosis of dementia difficult.

Scientists at Georgetown University have observed a relationship between resveratrol treatments and a protein called amyloid-beta40, which is a biomarker for Alzheimer’s. The results of this study were published Friday in the journal Neurology.

Alzheimer’s Disease has been one of the top leading causes of death in our country. It is understood that this disease is identified as an excess of the protein amyloid-ß within an increase of plaque (Seneff, Wainwright, and Mascitelli, 2010). Additionally, as the brain ages, it gets used to the inflammation and oxidative stress, so it is important to take the right amount of antioxidant micronutrients like vitamin C and vitamin E as well as anti-inflammatory macronutrients such as omega-3 polyunsaturated fatty acids to protect the brain from ageing (Whalley et. al, 2004). This is a devastating disease that affects most people over the age of fifty. Recently, there have been many studies done to figure out what causes this disease, if there is anything that can cure it, and how to prevent the disease. Seneff, Wainwright, and Mascitelli, believe Alzheimer’s develops with consuming too many carbohydrates, especially fructose and having a deficiency in cholesterol and dietary fats as well (2010). Whalley, Starr, and Deary have seen that poor diet, poverty, and failing health are links to developing Alzheimer’s Disease (2004). Furthermore, seeing increase in plasma homocysteine concentration increases risk of Dementia, which can result from an inadequate intake of vitamin B12/folate (Walley et. al, 2004). Additionally, Gray supports Walley’s findings and even believes having an adequate intake of vitamin B12/folate will have a positive effect on the overall health

Dementia is a syndrome which is progressive in nature, characterized by impairment of memory and loss of intellectual ability.1 Decreased level of Acetylcholine in the brain, neuro-inflammatory reaction, rise in the oxidative stress and hypercholesterolemia have been reported to play an important etiological role in the memory decline.2 Alzheimer’s Disease (AD) is the most common form of dementia which is a progressive and a neurodegenerative disease characterized by the presence of senile plaques rich in insoluble aggregates of β amyloid and neurofibrillary tangles in the brain. AD has been estimated to account for 50–60% of dementia cases in persons over 65 years of age worldwide.3 Alzheimer’s Disease International

As of now, there is no evidence showing that these therapies have the ability to slow the development of mental decline. Some treatments have been found to prolong the effects of Alzheimers. Omega-3 fatty acids are one of the many. Omega-3 fatty acids in fish oil help prevent cognitive decline. These are a clan of polyunsaturated fatty acids occasionally referred to ( n-3 fatty acids), this term describes their communal chemical structure. The omega-3 fatty acids differ in span from the shorter alpha-linolenic acid to the long-chain eicosapentaenoic acid and docosahexaenoic acid . Another treatment is Curcumin. This herb comes from the turmeric also this herb has anti-inflammatory and antioxidant belongings that affect chemical developments in the brain. Clinical hearings have not yet to create any benefits for treating Alzheimer's disease. And lastly Ginkgo. Ginkgo is a herbal extract that contains several substances that are thought to be possible benefit in

In order to alleviate the affects of Alzheimer’s disease, such as memory loss and build up of tau proteins, the natural substance Curcumin should be looked at (Hamaguchi, Ono, & Yamada, 2010). As an anti-inflammatory relative of the turmeric root, this natural, plant based substance shows promising qualities in reducing the effects of Alzheimer’s in mice. (Ma, Zuo, Yang, Ubeda, Gant, Alaverdyan, Teng, Hu, Chen, Maiti, Teter, Cole, & Frautschy, 2012). However, with no replicated studies done on humans, currently, the healing

2. The neuroprotective effect of resveratrol at large extent on the account of its anti-apoptosis effects.

With the growing number of people becoming diagnosed, and experiencing symptoms of Alzheimer’s disease, we must begin to take precautions and somehow attempt to gain knowledge of how the disease can be better treated, and ultimately prevented.

Wine corporations have made numerous claims that red wine has multiple health benefits, including heart health, longer life span, and even fights against some cancers. According to studies, a glass of red wine a day is beneficial to your heart health. Regarding whether or not this claim is true, goes beyond the myths and assumptions made by skeptics. To prove that this claim is, in fact valid, a chemical found in red wine, resveratrol is a chemical that is found within all plants (grapes in this case) that is used as a protection mechanism. But how does that affect a human consumer? According to scientific studies, the antioxidants found in this chemical compound has been found, in some cases, to be an asset in protecting one’s heart

Red wine contains resveratrol and guercetin, which are antioxidants that help prevent lung cancer and breast.