Multiple Sclerosis is an autoimmune disorder which is characterized by multiple areas of scarring to nerve fibers of the CNS. It often affects people between 20 to 40 years. Currently there are about 1.1 million people suffering from multiple sclerosis. Like most of the autoimmune diseases females are more affected than males in this disease. Multiple Sclerosis effects the central nervous system (brain and spinal cord). The disease commences with a discrete attack known as CIS (clinically isolated syndrome), which may attack any area of the CNS but mostly attacks either the brain stem, optic nerve or spinal cord.
The main cause of MS is yet to be known, researchers have suggested that MS is a demyelinating disease. Here myelin gets degenerated. Myelin is a material which is composed of fats and provides insulation for the nerves. This insulation of fat contributes in transmission of impulses with very high speed, allowing people to move almost without thinking. Therefore, when this myelin sheath is not present it cause a short circuiting like case and the person cannot move rapidly, smoothly and coordinate movements. According to researchers the immune system mistakes the myelin as a foreign body and attacks to destroy this myelin. It is not known yet what triggers the immune system but it is thought to be a combination of many factors. Among a few theories a virus that lies dormant in the body plays a major role in the causing of this disease by disturbing the immune system or indirectly contribute to the autoimmunity. Another one of the theories also says that it is not because of any specific virus but a common virus like herpes or measles which activates the …show more content…
Primary-progressive multiple sclerosis
3.Secondary-progressive multiple sclerosis which the most common type
4.Progressive-relapsing multiple sclerosis
• Initially MS shows vague symptoms like vision problems, swallowing, speech, cognitive
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Multiple Sclerosis (MS) is an autoimmune disease, in which the body's immune system attacks its own tissues. The disease destroys the myelin, which is the insulation that protects the nerve fibers in the spinal cord, and brain (Niino, 2008). When the myelin is damaged, the message that is traveling along that nerve may be slowed or blocked. Symptoms vary by patient, but often include: numbness or weakness in limbs, partial or complete loss of vision, lack of coordination or unsteady gait, slurred speech, fatigue, dizziness, and problems with bowel and bladder functions.
Multiple Sclerosis affects 2.3 million people worldwide. Multiple Sclerosis patients diagnosed are in the age range of twenty to fifty. Multiple Sclerosis effects the myelin in the central nervous system that disrupts the flow of information that is sent to the brain. This disruption effects your vision, mobility and bodily functions. Multiple Sclerosis has a wide variety of people it can effect. Your age, sex, where you grew up and even certain infections like Mono. There are a few tests that can be done to find out if you have Multiple Sclerosis, such as; MRI (Magnetic Resonance Imaging) this is not the only test but it is a huge
Multiple Sclerosis (MS) is a neurologic disease that affects the Central Nervous System (CNS) through cellular immune response and the demyelination of CNS white matter (McCance et al., 2014, pp. 630–633). The initial causes of MS are unknown however, it is believed that it could possibly be due to an immune response to an initiating infection or an autoimmune response to CNS antigens on the myelin itself (Brück, 2005) (Miljković and Spasojević, 2013). MS is a result of the degradation of the myelin sheath surrounding neurons and therefore disrupts the transmission of action potentials along these cells. MS can display itself in the form of symptoms ranging from muscle weakness to trouble with sensation and coordination (NHS, 2016). The degradation of myelin leads the body to attempt to remyelinate the neurons, a process that in turn leads to the thickening of the cell by glial cells and this causes lesions to form (Chari, 2007). It is this thickening (sclerae) from which the disease gets its name. Sufferers of MS can either have a relapsing type of MS, in which there are episodes that lead to the worsening of symptoms for a period of time, or a progressive type of MS where symptoms gradually progress and worsen (McCance et al., 2014, pp. 630–633).
The central nervous system (CNS) comprises grey matter, which contains neuron cell bodies and white matter, which contains the nerve axons. Most of the nerve axons are concentrically wrapped around by lipid-rich biological membrane, known as the myelin sheath. In the CNS, myelin is produced by oligodendrocyte. a type of glial cell. (Pfeiffer et al., 1993). These electrical insulating, multilamellar membranes significantly increase the electrical resistance, in which to prevent leakage of electrical currents from the axons, as well as decrease electrical capacitance to reduce the ability of the axons to store electrical energy (Shivane &
Multiple sclerosis is a chronic, progressive neurological disease affecting all aspects of life: physical, cognitive, emotional, and social (Abma). It is known as an autoimmune disease, Where the body’s immune system turns against the body and destroys the protective covering that surrounds nerve cells. This damage to the nerve cells causes many problems for the patient including weakness, muscle stiffness, poor coordination and balance, tingling, numbness, tremors, blurred vision, slurred speech, and memory and concentration problems (Bren)
Multiple Sclerosis (MS) is a chronic inflammatory disease of the central nervous system. MS affects approximately 3.0 million people globally, with about 300,000 cases in the United States. Twice as many women as men have MS. The average ages for onset of MS is 20-40 years. In MS, cells in the immune system attack and destroy myelin, the fatty tissue surrounding nerve cells (http://www.phylomed.com/MS.html). Scar tissue replaces the myelin, interfering with the transmission of nerve signals and leading to numbness, fatigue, spasticity, loss of muscle control, and various other debilitating symptoms. There are four broad theories
Multiple sclerosis, or MS, is a disease of the central nervous system. The central nervous system is made up of the brain and spinal cord. Both have nerve fibers that are wrapped in a myelin sheath. In MS, the myelin sheath becomes inflamed and gradually is destroyed. With the destruction of the myelin sheath comes an array of symptoms that may include numbness or tingling, balance problems, weakness, muscle spasms, and blurred vision.
M.S., as some would call it, also known as multiple sclerosis is a neurological disease. This disease, in particular, could also be viewed as an autoimmune disorder. It is not nearly as fatal as the sexually transmitted disease (AIDS), yet it can be just as debilitating. What exactly is Multiple Sclerosis? Multiple sclerosis is a disease in which the immune system malfunctions and begins to attack the myelin sheath. The myelin sheath is an insulating cover
Multiple Sclerosis is a disease that attacks the myelin coating over the nerve receptors in your brain and spinal cord. Myelin is a fatty material that coats and protects the nerves in your brain. These nerves send signals to the rest of your body enabling
Multiple Sclerosis (MS) is an autoimmune disease that attacks the central nervous system. The myelinated nerve cells get attacked which results in scars and lesions that destroy the myelin sheath. The reason for the body attacking its own nerve cells is unknown. Many believe that the cause of MS is from a virus, a deficiency in Vitamin D, or genetics. Studies are being done to find out what is the real cause of MS.
The causes for multiple sclerosis is unknown. It is an auto immune disease, which the immune system of the body attacks its own tissues. Multiple sclerosis is caused by damage of the myelin sheath. When the nerve covering is damaged, the nerve signals stops or slows down. The inflammation is caused by a nerve damage. This occurs in any region of the brain, optic nerve, and spinal cord. Women are more affected than men. Commonly diagnosed between ages 20 and 40, but it can be seen at any age.
Multiple Sclerosis, commonly known as MS is an autoimmune disease of the central nervous system. Scientists have been studying MS since the 19th century. In MS, the body’s immune system produces cells and antibodies that attack myelin in your brain which is essential for the nerves in your brain and spinal cord to conduct electricity to perform its function. The attack on myelin results in vison loss, paralysis, numbness, muscle weakness, difficulty walking, stiffness, spasms, and bladder and bowel problems. MS has varying degrees of severity and affects people between the ages of 20-50, mostly women. Although there are treatments, there is no cause and cure yet.
Multiple sclerosis, or MS as it is more commonly referred, is an immune mediated disease that involves the body's own defense mechanism, specialized immune cells, that ultimately attacks the central nervous system. Specifically, the myelin protein that coats axons and forms an electrically insulating layer for quicker processing of the nervous system, is attacked by cytotoxic cells that have crossed into the CNS. In a healthy patient, the blood brain barrier cannot be crossed by cytotoxic cells and it is speculated that an environmental component or outside source mediates this crossing. When the myelin is attacked, it forms scars in the CNS, as multiple sclerosis literally translates to “many scars,” which is the direct result of the disease. The scars disrupt the normal nerve impulses that travel through the central nervous system, and can cause a variety of symptoms including loss of cognition, fatigue, or numbness in the body (Evidence).
If you know anyone with Multiple Sclerosis or MS, you would know how terrible the disease is. Multiple Sclerosis is an inflammatory disease in which your immune system attacks the nerve cell covers in the brain and spine are damaged. The nerves in the body eventually deteriorate and it is fatal. According to the National Multiple Sclerosis Society, the cause of Multiple sclerosis is still unknown. There is not a cure at the moment for Multiple Sclerosis, but there are treatments that can speed recovery when attacked by the disease (Mayo Clinic). Scientists are under the impressions that there are a few factors that may come into play. They say that when they discover the exact cause of Multiple Sclerosis it will be easier to find a way to treat the disease or maybe even stop it from happening at all. (National Multiple Sclerosis Society)
Multiple sclerosis, also known as MS, is an autoimmune and inflammatory disease that is very painful for both the patient and care giver. In the disease, there is inflammation and neurodegeneration acting at the same time. There is currently no known primary cause of multiple sclerosis. The disease is however characterized by damaged fatty myelin sheaths around the axons of the brain and the spinal cord. Myelin is a mixture of proteins and phospholipids that protects many nerve fibers enabling speed at which impulses are conducted. It is pathologically characterized as the presence of glial scars all over in the central nervous system. The disease was discovered by the French neurologist Jean-Martin Charcot in 1868 when he examined the brain