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Biology of Cancer Study Guide

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Cancer Biology Section 1 Study questions

What is lifetime risk of getting cancer for men and women in US?
Male-1:2
Female-1:3 Which cancer are men mostly likely to get in the US? Women?
Male-Prostate
Female-Breast Which cancers are the most deadly and least deadly (US)?
Most deadly- Lung
Least deadly- non-melanoma skin cancer Name the cell-types that define carcinomas, sarcomas, lymphomas, and leukemia’s. Which type is most common?
Carcinomas- glands, organs and tissues, arise from epithelial cell lining external and internal body surfaces; most common cancer
Sarcomas- connective tissues (fat, bone, muscle)
Lymphomas- lymph nodes
Leukemias- bloodstream. Describe and identify normal tissues, tissues undergoing …show more content…

those who inherit hereditary nonpolyposis colon cancer (HNPCC) have higher likelihood of developing cancer
Other types of DNA Damage

Some chemicals can induce the loss of bases
Some chemicals can induce the modification of bases: Note: Conversion of C to U will result in a C:G to A:T mutation after replication
UV radiation induced pyrimidine (Mostly T) dimer formation. Explain the difference between the two classes of carcinogens: promoters and mutagens, and how they sometimes work together to increase the risk of cancer development. What is a complete carcinogen? How is the Ames test used?
Carcinogens: Substances

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