Bruton's Disease

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When an allergen enters the body, the immune system is alerted and reacts. It is attempting to protect the body from a substance believed to be harmful. Large amounts of immunoglobulin E antibodies are produced to the allergen. Histamine is released causing allergic symptoms, like itching skin or eyes and a runny nose. An immune disorder is a disruption in the body’s ability to defend itself against bacteria, disease or viruses. An example is Bruton’s disease. It is usually diagnosed in children and characterized by frequent infections. These patients have low or absent immunoglobulins and identified by the missing or defective Bruton’s agammaglobullinemia tyrosine kinase enzyme on the X chromosome.

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