Carboxylic acid synthesis, reactions and pharmacological activity Carboxylic acid is organic chemical compound that contain a functional group that is carboxyl group –COOH which is made of hydroxyl group and carbonyl group both attached to the same carbon which is attached to hydrogen atom or alkyl group thus the general formula of the carboxylic acid is R–COOH with R represent alkyl group or a hydrogen atom. Carboxylic acid functional group is partly ionized in solution so it is a weak acid, however it's acidity is considered as the chef chemical characteristic of it as it is generally more acidic than the other organic compounds that contain hydroxyl group and more acidic than the common organic functional groups but it is generally weaker than the common mineral acids such as hydrochloric acid (HCl). …show more content…
(1) 3D structure of a carboxylic …show more content…
All acid derivates can be hydrolyzed by water to yield carboxylic acids, the condition of this reaction are vary wildly from mild to severe conditions as it depend on the compound that is involved. The easiest acid derivate to hydrolyzed is acyl chloride because it require only the addition of water, carboxylic acid salts can be hydrolyzed simply at room temperature by the addition of water and strong acid such as hydrochloride acid (HCl) on the other hand carboxylic nitriles, esters and amides are less reactive and must be typically heated with water and a strong base or acid to be converted to carboxylic acids, if a base is used then a salt is formed instead of an acid which can be easily converted to an acid by the addition of hydrochloric acid, the amides are less reactive and require more vigorous treatment and nitriles can be partly hydrolyzed under milder
1. Carbon, hydrogen, and oxygen make up carbohydrates. Small carbs contain twice as many hydrogen atoms as oxygen atoms; simple sugars, called monosaccharides, are the basic building blocks for
The mole is a convenient unit for analyzing chemical reactions. Avogadro’s number is equal to the mole. The mass of a mole of any compound or element is the mass in grams that corresponds to the molecular formula, also known as the atomic mass. In this experiment, you will observe the reaction of iron nails with a solution of copper (II) chloride and determine the number of moles involved in the reaction. You will determine the number of moles of copper produced in the reaction of iron and copper (II) chloride, determine the number of moles of iron used up in the reaction of iron and copper (II) chloride, determine the ratio of moles of iron to moles of copper, and determine the number of atoms and formula units involved in
The purpose of this semester long experiment was to determine an unknown organic acid. An organic acid is an organic compound with acidic properties. A base reacts with acids to form salts. Titrations are used to determine the concentration of unknown substances. The purpose of the KHP experiment was to determine the molarity of NaOH. HCl titrations are mainly to check technique and used to verify the molarity of NaOH solution. The hypothesis is that this acid is C4H3OCOOH.
Hydrogens, alkyls, or aryls bonded to carboxyl groups—made up of a carbonyl group and a hydroxyl group—are known as carboxylic acids. Derivatives of carboxylic acids include acid chlorides, esters, anhydrides, amides, and generally nitriles. These derivatives are formed by the replacement of the hydroxyl group with a different electronegative heteroatom substituent, which can be a single atom, such as a chlorine atom, or a group of atoms, such as in the formation of
Three grams of a mixture containing Benzoic Acid and Naphthalene was obtained and placed in 100 ml beaker and added 30 ml of ethyl acetate for dissolving the mixture. A small amount (1-2 drops) of this mixture was separated into a test tube. This test tube was covered and labelled as “M” (mixture). This was set to the side and used the following week for the second part of lab. The content in the beaker was then transferred into separatory funnel. 10 ml of 1 M NaOH added to the content and placed the stopper in the funnel. In the hood separatory funnel was gently shaken for approximately one minute and vent the air out for five seconds. We repeated the same process in the same manner one more time by adding 10ml of 1M NaOH.
Introduction: Reaction of a compound with water can result in a splitting, or lysis, of the compound into two parts. Organic molecules containing a group of atoms called an ester can be hydrolyzed by water to form a –COOH group (carboxylic acid) and an HO-- group (alcohol) as follows:
The purpose of this lab was to identify unknown bacteria cultures using various differential tests, and my unknown bacteria is #17. The identification of these unknown cultures was accomplished by separating and differentiating possible bacteria based on specific biochemical characteristics. Whether the tests performed identified specific enzymatic reactions or metabolic pathways, each was used in a way to help recognize those specifics and identify the unknown cultures. The differential tests used to identify the unknown cultures were Gram stain, Catalase, Mannitol Salt Agar (MSA), Blood Agar, Novobiocin, Coagulase, and DNAse (Alachi, 2007).
In this experiment, an alkyne—diphenylacetylene—was prepared by a double dehydrobromination. Potassium hydroxide (KOH) and high heat were used to accomplish this. The precipitate of this reaction was collected by vacuum filtration. It was then washed with water and recrystallized using ethanol. The product was then isolated again before the weight was taken for further analysis of percent yield. The melting point was also taken to identify that it was the desired product.
The goal of this was to successfully accomplish the synthesis of para-Chlorophenoxyacetic acid. In this experiment, para-Chlorophenoxyacetic acid was synthesized from 4-chlorophenolate and chloroacetic acid using an SN2 reaction. The product obtained was determined to be the para isomer of Chlorophenoxyacetic acid. This was confirmed by the melting point of 157.3-157.9 ◦C. The percent yield determined at the end of the experiment was 37.83 %. The TLC analysis showed that P-Chlorophenol was less polar than P-Chlorophenoxyacetic Acid because it had an Rf value of 0.38 in comparison to the value of 0.33 on a 50:50 hexane and ethyl acetate solvent mixture. In the NMR comparison, it was shown that both the starting material of chloroacetic acid and product contained a peak of integration two around 4 ppm representing the acidic proton. In the FT-IR comparison, it was determined that the Chloroacetic acid and the para-Chlorophenoxyacetic acid both had an OH bond at 3416 cm-1 and 3429.72 cm-1 respectively. The Chloroacetic acid and para-Chlorophenoxyacetic acid also both had a carbon-oxygen double bond at 1648 cm-1 and 1654.81 cm-1 respectively. The para-Chlorophenoxyacetic acid also contained a peak at 1236.18 cm-1 which represents the C-O-C bond.
Table 2: Consists of color extract taken from a red cabbage for a natural indicator. The pH reading that was measured by using the pH meter and the result of the pH reading to determine whether the solution was acidic or basic.
2. (5 pts) List and explain the names and affiliations of the various characters/stakeholders in this story – I’m looking for us to use the story to map out the complexities that are generally associated with solving public health puzzles – the stakeholders you list and explain here should apply to many of the cases we consider going forward.
In a test tube, 0.5mL of the sample will be added with 0.5 mL of water and shaken vigorously. Take note for its solubility by parts (0.5mL is one part). Keep adding parts of the solvent until the sample is soluble. If not, add until ten parts of the solvent and determine its solubility. To separate test tubes, water will be replaced with ethanol, chloroform, ether, and acetone as solvents. Same procedures were
Dispense .5 mL water into the already weighed conical vial, replace cap and face insert on its down side.
Stoichiometry is a method scientists use to presume how two or more substances will react together. In order to do so successfully, the reactants are positioned on the left and the products on the right. The most important part of successfully
HCl is known as Hydrogen chloride in its gas state, but when in the presence of water, it is known as hydrochloric acid(PubChem). Hydrochloric acid is extremely corrosive and has uses in both laboratories and industrial settings(PubChem). This acid can cause short term complications such as irritation to the eyes and nose or it can leave long term effects like dermatitis and chronic bronchitis (PubChem). Sodium hydroxide is a base that neutralizes acids and when in liquid form it has a higher density than water (PubChem). The compound is used in various textile industries (PubChem). NaOH can be corrosive to metals and is toxic if ingested (PubChem).