During the 1800’s, cocaine was first created and recognized for its medicinal purposes. “Cocaine is a powerful stimulant drug made from the leaves of the South American coca plant” (“Stimulants”). Cocaine was initially being used as a medicinal drug to reduce the pain of toothaches or as a local anesthesia used for certain surgeries. Shortly after, a new popular drink by the name of “Coca Cola” was created and contained a small amount of cocaine to provide the users with an increase of energy. During this time in the United States the drug was considered to be legal and people of all classes were engaging in risky behavior taking the drug. Around the 1920’s, the United States placed cocaine on the list of narcotics which classified it as a drug making it illegal to use the drug recreationally. By the time cocaine became illegal thousands of Americans had already grown a dependency towards the drug and would seek it out on the black market to feed their addiction and not go into withdrawals. In recent years, cocaine use has become an epidemic being one of the most used drugs in the United States, second to marijuana. An addiction to cocaine can have detrimental effects on the human body. The use of cocaine has many different and negative effects on the human brain. “Cocaine increases levels of the natural chemical messenger dopamine in brain circuits controlling pleasure and movement” (“DrugFacts-Cocaine”). The average human brain will release dopamine in order to send
Cocaine, a narcotic drug that took the entire world by storm in the 1980’s, has continued to find it’s way into countries all over the world. The drug is a highly addictive stimulant that is extracted from the leaves of the Erythroxylon coca bush, which is indigenous to the Andean highlands of South America. It comes in two main forms, powder and crystalline, also known as “crack” (“Cocaine Use and Its Effects”). Although the short term effects of cocaine seem somewhat harmless, the long term effects are devastating and have ruined the lives of many users. The short and long term effects of cocaine can be seen on Ishmael Beah, and his companions in the novel A Long Way Gone by Ishmael Beah.
The long term effects of cocaine are very extreme. Once having tried cocaine, an individual may have difficulty controlling the urge to use the drug and the perspective might change leaving the consumption of the drug as primordial. Cocaine’s stimulant and addictive effects are due primarily as a result of its ability to stop the reabsorption of dopamine by nerve
Cocaine is one of the oldest, most powerful and most dangerous stimulants in the world. This powerfully addictive drug effects over 35 million people In the United States. Cocaine addiction prevents a person from being a productive member in our society. It also increases the cost for law enforcement and treatment facilities. It rapidly decreases the workplace, increases the homeless rate and needless deaths on a daily basis.
Drugs have a particularly interesting history within the United States. Many of the well-known and highly addictive narcotics of today like heroin, cocaine, and opium, were previously used in a variety of mundane ways. They were present in drinks and in health tonics/elixirs for treatment of an array of illnesses and as pain relief (“What is Cocaine?”, 2016). Perhaps the most consumed soft drink of all time, Coca Cola, derived its name from the coca plant – giving a glimpse into its cocaine containing past. However, it was not soon after, that drugs began to lose their credibility about their effectiveness in food and medicine. By the early 1900s, they were
For short-term use, cocaine can provide extreme happiness, enhanced sensitivity to sound and touch or mental alertness. People takes cocaine as it can provide energy on their work but a long-term use of cocaine may lead to malnourishment, irritability, restlessness, paranoia and auditory hallucination (NIDA, 2016; Roncero, C., et al., 2013). Also, cocaine abuse may have other complications such as nosebleed because of snorting, difficulties in swallowing and easily infected by HIV or hepatitis C through needle injection and the misjudgment on having unsafe sex (NIDA, 2016). On the other hand, long-term use of cocaine may lead to addiction and a stronger dosage will be taken when they have any withdrawal symptoms. For instance, symptoms of depression, fatigue and increased appetite. Nowadays, still no medicines were approved for treating the addiction on cocaine and thus the treatment of cocaine addiction is
One of the most detrimental and addictive narcotics in the world today is cocaine. Cocaine dates back as early as 3000 BC. Ancient Incas used the coca leaves to counter the effects of living in thin mountain air. Native Peruvians in the 1500’s chewed the plant strictly for religious ceremonies. Andean Indians are believed to chew the leaves of the coca plant to increase their energy for work while decreasing their hunger and pain. It wasn’t until 1859 when a German chemist Albert Niemann successfully extracted the narcotic from the coca leaf. In the 1880’s, it was freely prescribed by physicians for “maladies as exhaustion, depression, and morphine addiction and was available in many patent medicines” (“Cocaine”), until users and doctors began to realize its dangers and side effects. While it was not fully understood at the time, cocaine has many devastating and lasting effects on the user.
Cocaine’s mode of action has been shown to involve the dopamine receptors. This paper will discuss how cocaine affects dopamine receptors, the mode of addiction, how cocaine affects the frontal brain metabolic activities, as well as the role of excitatory amino acids in cocaine’s mechanism. I will also discuss how cocaine affects another system through its mechanism on the brain—the renin angiotensin system.
It is composed of many functional groups, which explain for the different types of functions. Cocaine has an educational background both in science and in history. It has been used recreationally throughout history and made its way to the European continent and other areas after the European colonized in South America. The native people of South America used to chew on coca leaves to extract the compound and use it as a source for energy and power to complete daily tasks. There is also evidence of the natives using this coca leave for medicine. The medicine component behind cocaine dates back to centuries ago. The skeletal remains show that some people used to chew on it as they were going through a medical procedure. These people had residue left in their cheekbones, and there was a hole in their skull. This signified that the people went through a medical procedure to get treatment for brain illnesses. The ones without these holes show that it was being used recreationally. It has a rich, detailed scientific background as many people sought to uncover the pure substance. Uncovering the pure substance only lead to further advancement in medicine; Cocaine was being used as a local anesthetic. People further went on to create derivatives of cocaine, which are the more popular anesthetics used in medicine right now. Some of these anesthetics include Benzocaine and Lidocaine. These anesthetics are typically used to treat ulcers. Cocaine, today, seems to be more of a social issue due to numerous people abusing the drug and getting addicted. It is evident that there are beneficial and detrimental uses of the drug. Cocaine can cause harm when it is abused or used in the wrong way. It can lead to serious complications and consequences. However, Cocaine also has great application in the medical field. It can be used as a good way and lead to many
Cocaine is an addictive stimulant, and it is known to be the strongest natural stimulant in today’s
Cocaine also known as crack cocaine is a stimulant drug, a stimulant raises one’s heart rate, attention and awareness and breathing. Stimulants were used to treat respiratory issues but is now prescribed for individuals with ADHD. In the 1800’s is when cocaine began to be seen as an addicting substance due it’s mood-altering effects on one’s brain. Cocaine can be inhaled through a pipe, when in powder form it can be snorted, and some individuals inject the drug into their bloodstream through intermuscular or intravenously. Individuals that use cocaine repeatedly use the drug within a short time span between each time used so that the euphoric high stays longer. The effects that cocaine has on the central nervous system is so
Cocaine is one of the most euphoric, exciting, fun substances in the world - and also the most dangerous. It creates the perfect feeling, the invincible high. It is so strong and has so many beneficial qualities that it was once called the miracle drug, but the miracle drug has its downsides too. The miracle drug is dangerous. The miracle drug is deadly. Cocaine is a highly addictive and dangerous drug that alters the mind and body of humans of all ages and consequently changes their entire thought process. It chemically alters the mind, increases the physical ability of people (while also destroying their bodies) and morphs their entire mental state into something great (while also turning them into paranoid schizophrenics).
Cocaine has been shown to be the most common, most potent stimulant out there. It was found in the leaves of the erythroxylon coca plant in the Andean highlands, and it was used for many centuries as a relaxant and energizing tea by natives. It was used in surgeries to numb the nose, throat or eyes. It was useful in these areas because it constricted blood vessels and helped stop blood flow as well as acted as an anesthetic (Virtual Mass Spectrometry Laboratory 2003). Today cocaine is still used in hospitals for the same reason. Cocaine was also thought to be used to treat depression, alcoholism, and addiction to morphine. It was sold in pharmacies in Canada until around 1911. It made a return in the 1960s. Cocaine is illegal and is sold
This article focuses on examining how the brain effects cocaine dependent individuals and treatment. The first section primarily focuses on providing a biopsychosocial description of cocaine addiction or dependence based on recent research findings. This description includes a discussion on the evolution of cocaine dependence to become a major public health issue. This is followed by an evaluation of the social impact of the problem. The analysis is carried out on the premise on why cocaine dependence and
In order to fully understand addiction, one must examine the pathways and circuits in the brain as well as the genetic attributions that form this type of behavior. It is important to note that addiction has various forms such as with substances (alcohol, tobacco, drugs) and behavioral addictions (food, sex, shopping). With the forms listed and the many other types of addiction that are out there, they all contribute to alterations in brain structure and function. This article focuses on a particular addiction- cocaine addiction- and how it impacts gene expression and neuronal function. Like other substances of abuse, cocaine users have behaviors that cause them to compulsively take the drug with a loss of control in amount. Even with
Discovering an effective pharmacotherapy for cocaine use disorder remains a top research priority nationally since there are currently no FDA approved medication for the treatment of cocaine dependence. While several classes of medications have shown some efficacy in some phase two clinical trials, none has been proven to show consistency and lasting efficacy. Recent progress in the understanding of the effect of cocaine on the