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Hippocampus Memory Annotated Bibliography

Decent Essays

Annotated Bibliography
Eldridge, L.L., Knowlton, B.J., Furmanski, C.S., Bookhemer, S.Y., &Engel, S.A. (2000)
Remembering episodes: a selective role for the hippocampus during retrieval.
Nature Neuroscience, Volume 3, pg 1149-1152.
Some researchers hypothesize that the hippocampus is involved in some types of memory processes but not others. This particular study measured brain activity using fMRI during two types of memory tasks: remember (episodic memory) and know (familiarity). A memory was considered “episodic” if the person could recall the moment it was learned and “familiar” if they felt they recognized the word but could not retrieve the specidic moment it was learned. The a priori (pre-selected) region of interest( ROI) in the hippocampus …show more content…

Among these different processes are encoding, storage, consolidation, and retrieval. This study hypothesized that the hippocampus plays a different role in each of these. The method of this study is especially unique because it used temporary chemical inactivation of the hippocampus, which had not been done before. This temporary inactivation is unique because it lets the researchers selectively assess the role of the hippocampus during each of the processes discussed above. To test encoding, the inactivation occurred during learning of a maze task; to test retrieval, inactivation occurred during a retention task. Results indicate the temporary inactivation of the hippocampus impairs both encoding and retrieval. To test long-term consolidation, rats were trained and then separate groups received hippocampal treatment for different amounts of time between one and five days. Results showed that temporary inactivation during this time period disrupts memory for the already learned task. This study partially supports the result of the study by Eldridge et al. (2000) in that they both show the hippocampus is necessary for memory retrieval. However, it does not address the retrieval of different types of memory. This study also supports the idea from Wang et al. (2012) that the hippocampus may be involved in consolidation and storage of new memories but not necessarily of older

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