Huntington's Disease Research Paper

Huntington's disease is an inherited neurodegenerative disorder. It is passed on to children from one or both parents (though two parents with Huntington's is extraordinarily rare) in an autosomal dominant manner. This is different from autosomal recessive disorder, which requires two altered genes (one from each parent) to inherit the disorder.

Huntington’s disease destroys the organs that carry the functions of the central nervous system. Kalat (2013) states, “Huntington disease (also known as Huntington disease or Huntington’s Chorea) is a severe neurological disorder that strikes about 1 person in 10,000 in the United States” (A.B. Young, 1995, p. 258).Individual’s develop the symptoms in their middle age, but even if it is a rare disorders juveniles as well as children before the age of ten can develop the disease. Huntington’s disease is hereditary disease that is passed on from a parent. Huntington’s disease is of the lack of the chromosome 4, if one of the parents carries the gene, they can pass that gene to their

Huntington's Disease (HD) is a disability that will continue to get worse and worse over time. The lifespan for someone living with HD is 10 to 25 years after they are diagnosed and showing symptoms, which is usually around the ages of 30 to 50 ("What Is Huntington's Disease," 2017). These symptoms begin at different times and depend on the individual. Overtime, the person affected will begin to lose their ability to walk, talk, and eat over the course of these 10 to 25 years resulting in the need for 24 hour care.

Huntington’s Disease is a dominant, autosomal, neurodegenerative disease that results from excess CAG repeats on the human chromosome 4. These CAG repeats code for a protein named Huntingtin, and patients of Huntington's Disease have a mutated form of it. Symptoms begin to appear in one’s middle ages and continue to progress over a span of about 20 years. It leads to loss of mental ability and muscle coordination, as well as increasing one’s vulnerability to depression. Those who develop Huntington’s Disease cannot be cured, but there is treatment to reduce the mental and physical effects. Genetic advancements in both testing and treating Huntington’s Disease have provided hope for families with a history of this disease, but it has

Huntington disease is defined by the autosomal pattern that is in inheritance with high penetrance of high proportion of the population that has the gene that advances the disease. It’s typical that Huntington disease is caused by the loss of neurons nerve cells in the brain (Van Walsem M.R, 2016).

Envision a life that is completely normal, walking and talking, running and playing, driving. However, then life begins to change. The person starts to stutter when speaking. Walking becomes difficult as the person trips over their own feet with jerky movements and even falls. Eventually, the ability to walk disappears and a wheelchair is the norm. No more running, playing, or driving. Balance and memory problems will appear in due course. Subsequently, even eating may be complicated leading to the possibility of a feeding tube. Loss of physical and mental abilities will progressively become worse. Ultimately, a long-term care facility may be in the future. This is the progression and life of a person with Huntington’s

Huntington’s disease is a hereditary brain disorder that affects people all over the world. If your parent has this disease, there is a fifty-percent chance that you will develop it at some point in your life. Huntington’s disease is caused by a defect in the dominate gene called huntingtin. This defect is caused by a part of DNA called CAG repeat. Normally the huntingtin gene is repeated about ten to twenty-eight times, and plays a major role in brain development. When a person has Huntington’s disease the huntingtin disease repeats anywhere from 36 to 120 times. When the gene repeats this much the elongated proteins separate into smaller pieces and collect neutrons, disrupting the normal cell function. This effects the parts of the brain

Many of you may not know much about Huntington’s disease. After reading this paper and the subsequent ones to come, you surely will. According to PudMedHealth.com, “Huntington’s disease is a disorder passed down through families in which nerve cells in certain parts of the brain waste away or degenerate.” This can lead to many different complications to a person’s health. In most cases, the disease’s symptoms develop later in life during a person’s mid thirties-forties. There are also instances where the disease becomes on-set in children or during adolescence. The question that I am writing about is the disease itself ,and which symptoms affect you the worst. The reason I chose to write about this disease is because I have always been

Gene is the basic unit of heredity in a living organism. It is also composed of the DNA (deoxyribonucleic acid). Huntington's disease is caused by abnormal genes in the nerve cells in the brain. In the global population Huntington's disease evaluates that for every 100,000 people 5-10 people are going to have Huntington's disease. In the United States, 30,000 are affected by Huntington's disease and 150,000 people have 50 percent risk of evolving this disease. Moreover, in middle east countries Huntington's disease is estimated to affect 3-4 people per 100,000. Explaining the history, meaning and how the genes of Huntington's disease inherited helps to realize the disease and its risk.

Huntington’s disease (or Huntington’s chorea) is a hereditary degenerative disease that affects the cerebral cortex and basal ganglia. It is a progressive brain disease that targets the ability to move, loss of the ability to think, and emotional problems. The most common form of Huntington’s is adult onset, appearing in the thirties or forties. As the disease advances,

Huntington’s disease is an inherited disorder of the central nervous system, and the degeneration of nerve cells in the brain, which causes the brain to deteriorate.

Huntington 's disease is a dynamic, neurological disorder. Tragically, it doesn 't demonstrate manifestations until people have reached they’re 30 's or more. 'Children whose parent 's have this genetic disorder have a 50-50 ' ( ) possibility of acquiring the trait.

Huntington’s disease is a neurodegenerative disorder that is inherited in an autosomal dominant fashion. The cytoplasmic protein affected in Huntington’s disease is Huntingtin, coded for by the Huntingtin gene. The mutated version of the Huntingtin protein has several degenerative consequences on the molecular level. These are mainly caused by the elongated chain of glutamines that abberantly interacts with proteins and diminishes their biological functions. The mutated protein also tends to misfold and form aggregates in neurons, diminishing normal neural functions and producing the phenotypic traits characterized by Huntington’s disease.

Huntington’s disease is know to be one of the inherited disorder causes deterioration in human brain cells called Neurons as well as other part of the brain. More than 30,000 Americans have this disease1. Huntington disease can occur

Huntington disease is a genetic disorder that has affect many people. The Huntington disease is commonly known as Huntington Chorea (Genetics Home Reference ). The disease was first recognized in 1872 by George Huntington (Phillips). George Huntington wrote a paper called On Chorea and “chorea” is Latin and Greek for chorus or a group of dances (Phillips). In the Middle Ages this term was given to many “dancing disorders” (Phillips). People with chorea basically had involuntary muscle jerking and twitches (Phillips).