It is known that isoflavones are beneficial to overall health. Because isoflavones are found naturally in fruits and vegetables, a diet high in fruits and vegetables is important1.
All isoflavones have been shown to help with different aspects of cognition in one form or another1. Specifically, soy isoflavones have been researched to have some encouraging benefits in cognition, but it is still to be researched for the mechanism of action and exact amounts that are needed to be beneficial2.
One cognitive defect affecting elderly patients is Alzheimer's disease. This cognitive disease affects many populations around the world, but mainly aging individuals3. Though the quantity of life is extending with modern medical practices4,
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This would help with monitoring possible data points such as vitals and help to control the participants’ diets. This would present a population with a mixed socioeconomic status, since some individuals will be private pay and others may have coverage from insurance7. The population would include both men and women. Since these patients have cognitive difficulties, it would be best to have the power of attorney or next of kin to help provide informed consent6. A baseline cognition exam should be performed on all patients using the Weschsler Memory Scale8. Inclusion criteria would include standard Alzheimer’s medications, as long as they have been used for two or more months6. This is to control the possibility of a different possible experimental medication being used at the same time as this study. Exclusion criteria would include other cognitive illnesses that impair memory, as well as cancer6. It is best to have patients with only one memory-impairing disease to be sure any positive or negative correlations are limited to the disease of interest. The exclusion would also include participants who have higher than normal levels of lipoprotein lipase6,9. By only utilizing nursing home populations, there is the exclusion of other possible participants, resulting in missing data. These would likely consist of volunteers or candidates recommended by physicians. This would result in a lower sample size and less encompassing data.
The methods and design necessary
The disease called Alzheimer’s is the fourth leading cause of death in the United States (Weiner, 1987). It is estimated that the elderly population will double between now and 2030. During this period, the number of elderly will grow by an average of 2.8% annually (U.S. Census Bureau, 2001). By 2050, the number of people with Alzheimer’s is estimated to range from 11.3 million to 16 million (Alzheimer’s Association, 2005). These startling numbers should prompt an examination into one of the leading causes of death among this group of people. Understanding what Alzheimer’s is and the known causes of the disease are a good starting point. For those who have aging family members, knowing the risk factors and warning
Dementia can be defined as a decline in mental ability severe enough to interfere with daily life (alz.org). More than often, individuals affected by dementia are over the age of 65. In the United States, there are more than three million cases of dementia each year. According to World Health Organization, the number of people living with dementia is currently estimated at 47.5 million worldwide and is expected to increase to 75.6 million by 2030 (World Health Organization 2015). Dementia is caused by physical modifications in the brain and is known for loss of memory and mental abilities. It’s a progressive disease which means it gets worse over time. If diagnosed early on, the quality of life for people with dementia as well as their family members can be significantly improved. There are many different types of dementias although some are far more reciprocal than others. One of the most common types of dementia is Alzheimer’s disease. Other few types of dementias are “Vascular dementia, Mixed dementia, Parkinson 's disease and Frontotemporal dementia (Krishnan, D. S)”. All of the various forms of dementia tend to have similar symptoms which consequently makes it hard to determine the type of dementia a patient may be suffering from.
An estimated 47.5 million people suffer from dementia. Every 4 seconds one new case of dementia is diagnosed. Dementia is a term that describes certain symptoms such as impairment to memory, communication and thinking. It is a group of symptoms and not just one illness. Even though one‘s chance of getting dementia increase with age, it is not a part of aging. Dementia is usually diagnosed after a series of assessments that includes a physical evaluation, memory tests, imaging studies and blood work. It affects three aspects of one’s mental function, cognitive dysfunction (Problems with memory, language, thinking and problem solving), psychiatric behavior (changes in personality, emotional control, social behavior and delusions) and difficulties with daily living activities (driving, shopping, eating and dressing). “The median survival time in women is 4.6 years and in men 4.1 years” (Warren, 2016).
Throughout history there have been reports of decreased memory and mental deterioration that accompanied old age. Alzheimer’s disease (AD) was named after Dr. Alois Alzheimer who described the symptoms in a woman in Germany in the 1907 but it was not until the 1970’s that AD was considered to be a major disorder and AD continues to be a major health concern worldwide (Reger, 2002).
Dementia is a drastic failure of cognitive ability that correlates with shrinkage of the hippocampus; the greater the impairment, the likely the smaller the size of the hippocampus. Alzheimer’s Disease is a neurodegenerative disorder, and a form of senile dementia that is characterized by progressive cognitive and sensory impairment in the form of: having a greater difficulty performing tasks, forgetting material that one just read, memory loss, slowed metabolism and atrophy and loss of awareness. With Alzheimer’s being the most common form of dementia, it is estimated that the disease affects 10% of people by the age of 65 and over 50% of people over the age of 85. This disease
Alzheimer 's disease which chronically leads to Senile Dementia, is a horrific change in homeostasis for human beings. The most obvious change in homeostasis from Alzheimer 's is loss of memory. Memory loss can vary from short term to long term. Alzheimer 's disease has been occurring in humans for a long time. This is a disease that affects different body systems, and interrupts homeostasis to a significant point. As Alzheimer 's disease is further investigated, there are more discoveries with how it is caused, what it affects, and how to reduce the risk of developing it. Alzheimer 's disease is a frightening disease that is represented in humans. There are many concerns with this disease that are worth finding out for the future victims
This study will investigate and test how some medications can smooth the progressive advance of the Alzheimer in patients with more than 70 years. Alzheimer which is a degenerative disease of the neuro system due to memory loss is still being very questionable and debated. As of today there is no cure, nor reversal for the disease. Many researchers are still studding and looking for therapies and medication that can stop or reverse the development of the disease. It is very important to prove that some medications can help to cope with the disease. In my study I will be able to demonstrate
Alzheimer’s disease is an irreversible, progressive brain disease that slowly destroys memory and thinking skills. “Its onset is generally insidious, with gradual deterioration of cognitive function, eventually resulting death.” (Falvo, D. 2009, pg. 226). Alzheimer’s is the most common form of dementia among people age 65 and older. “Nearly 70 percentages of all dementias are Alzheimer’s, and over 4.5 million Americans have Alzheimer’s.”(www.alz.org). This disease is not just a disease that happens to older people, but there is a small percentage that can also affect those in their 30s.
The alzheimer’s disease is a progressive disease that destroys memory and other important mental functions. Alzheimer's is not a normal part of aging and only up to 5 percent of people with the disease have early onset Alzheimer's (also known as younger-onset), which often appears when someone is in their 40s or 50s. This disease doesn’t have a cure, but there are treatments for symptoms available and research still continues to find the answer to cure this bad disease. Also, an interesting fact is that ninety percent of what we know about Alzheimer's has been discovered in the last 15 years. Lastly, Alzheimer's is a progressive disease, where dementia symptoms gradually worsen over a number of years. In its early stages, memory loss is mild, but with late-stage Alzheimer's, individuals lose the ability to carry on a conversation and respond to their environment. It’s the sixth leading cause of death in the United
Alzheimer’s, a severe irreversible form of dementia, is now a very prevalent issue in the aging population. Scientists are just beginning to understand what Alzheimer’s is, what causes Alzheimer’s and how to prevent it. Although research has come a long way, “Alzheimer’s disease, as science tries to grasp it, seems to slip through our fingers. The complex interaction of neurochemistry, genetics, environment, lifestyle and personality all play a part in how individuals experience Alzheimer’s. ~ Harry Clayton
As we age, our bodies begin to deteriorate. The bones become brittle, the muscles and tendons atrophy, hair falls out, and our mental faculties begin to diminish. It can be difficult when it comes to aging but at times it is a beautiful, natural process of life. With age comes many difficulties and changes. One of them is a very serious and debilitating change that can impact one who is affected as well as those who may be caring for them and their families. This change is that of the disease Alzheimer’s. Alzheimer’s is a progressive disease that destroys memory and other important mental functions. This disease affects more than 5 million Americans and continues to increase. With this disease on the increase, it begs the question if there is a way to prevent this debilitating disease or at least some kind of early diagnosis. Though there is no concrete way to determine the etiology of Alzheimer’s unless through autopsy of the human brain, there are ways to aid in the early diagnosis of this disease amongst the aging population for better and improved prognosis.
Alzheimer’s disease is a very slowly progressive disease that occurs inside the brain in which is characterized by damage of memory. Also this type of disease can lead into interruption in language, problem solving, planning and perception. The chance of a person developing Alzheimer’s disease increases enormously after the age of 70 (Crystal, 2009). Also people who are over the age of 85 have over a 50 percent chance of developing Alzheimer’s disease. This type of disease is not at all normal in the aging process and is also not something that happens out of no where in a person’s life.
The second study the researchers conducted included 94 people ranging in age from 62 to 80. They were divided into four groups. The people in this study didn't have noted cognitive issues, but they felt their memories were diminishing. The groups were given placebo, blueberry powder, fish oil or a combination of fish oil and powder. The results weren't as profound as the first study. Researchers feel the reason for this may be because the participants had less severe memory problems when they joined the study.
In addition, the properties also help with cognitive function improvement, which is very crucial in both memory and concentration.
Studies have shown that blueberries are able to reduce the effects of any cognitive damage that are usually brought on by the natural aging process. Participants relying on blueberries have constantly fared better on memory tests than other participants who are put on placebo treatment.