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Ischemic Stroke Research Paper

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Stroke is the fourth leading cause of death in the United States and the leading cause of disability, with ischemic stroke comprising more than 80% of total stroke cases. Ischemic stroke is caused by obstruction of blood vessels supplying blood to the brain by thrombus or embolus. Recombinant tissue plasminogen activation (rtPA) is currently the only approved acute treatment for ischemic stroke. ROS production is significant increased as soon as the occlusion occurs. If blood clots were removed in a timely manner, significant brain damage could be avoided. Cells in the ischemic core region usually die of infarction, while cells adjacent to the infarct region, penumbra, could be saved by appropriate therapeutic strategies. The residual blood

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