Measles Virus ( Mv )

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Measles virus (MV) has been well established in the world, as the most transmissible viral agent in humankind and it’s considered as the primary cause of death in children globally. The persistent of Measles viral infection throughout the centuries has given the opportunity for scientists to investigate the Morbilivirus genus family where MV belongs. It has been found that every virus belonging to the Morbillivirus family, share a negative-strand linear RNA genome and a spherical envelope that surround the genome. In addition to that, all the virus species belonging to the Morbillivirus genus family, encode for eight proteins that are crucial for the invasion, multicipility and the survival of the virus [1]. This known virus family therefore is consisted of six species: Rinderpest Virus (RV), Phocine Distemper virus (PDV), Cetacean morbilliviruses (ceMV), Peste des Petits Ruminants (PPRV), Canine Distemper Virus (CDV) and Measles Virus (MeV). Apart from their common features however, these species show also to be phylogenetically related as it can be observed from the tree below (Fig 1.) An important observation is how closely MV is related with RPV and how least related is with CDV, showing a possible link between their infecting hosts [17]. Figure 1: Morbillivirus Phylogenetic Tree that shows how similar or diverse morbillivirus species are. Available online at: http://www.mdpi.com/1999-4915/7/2/699/html Its invasion tactic often results in acute disease symptoms
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