Medication Synthesis Paper

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Medication Synthesis Week Seven A twenty-five-year old Caucasian female presented to the office with burning with urination. External inspection of the patient’s labia majora revealed genital herpes. Herpes simplex virus infections associated with the genitals are usually deemed type two (Uphold & Graham, 2013). The patient was placed on acyclovir for her outbreak. The current dosage that she is being placed on is 400 mg orally every eight hours for ten days (Medscape, n.d.). There are no medication contraindications for this drug; however, one should not use neomycin orally due to an increase in nephrotoxicity and or otoxicity if the two are taken together (Medscape, n.d.). Other medications such as bacitracin and cidofovir should also not be used with acyclovir due to an increase in nephrotoxicity and or otoxicity if these are …show more content…

Adverse effects of acyclovir are malaise, nausea, vomiting, diarrhea and headache (Medscape, n.d.). Less than one percent of individuals taking acyclovir experienced abdominal pain, aggression, agitation, anemia, and anorexia (Medscape, n.d.). According to the Centers for Disease Control and Prevention (2015), systemic antiviral drugs only partially control an outbreak of genital herpes when they are used to a first clinical episode. Individuals who experience their first outbreak should receive antiviral therapy (CDC, 2015). The mechanism of action to acyclovir is that it “interferes with DNA polymerase to inhibit DNA replication via chain termination” (CDC, 2015, para. 1). Systemic acyclovir is widely distributed throughout the body including the brain, kidneys, lungs, spleen, muscle,

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