Melanoma Skin Cancer Essay

Unlike other cancers which we can develop, melanoma can often be detected on the skin which allows doctors to treat it at its early stages resulting in less complications and lower death rates to patients, again if left undetected at its early stages this can easily spread to distant areas and distant organs. Once melanoma has spread to other areas of the body which is classified as stage IV it is diagnosed as

all other cancers combined. This includes breast cancer, colon cancer and lung cancer (Skin Cancer Foundation).

Although there are several types of skin cancer, the most aggressive form is melanoma. This cancer of the skin involves mass replication of the pigment producing melanocyte cells, which are located in the epidermis, below the basal layer. There are several factors involved with the onset of melanoma including, exposure to ultraviolet rays, genetic predisposition, numerous nevi (moles), immunosuppression, and environmental exposure to carcinogens.

The basic component in tanning is ultraviolet light. Ultraviolet light, whether produced by a tanning unit or by the sun, contains two components; UVA and UVB. These are the two types of ultraviolet radiation that are known to negatively effect the skin. UVA has a longer wavelength that causes photoaging and can produce some melanomas. UVB has a shorter wavelength that also causes photoaging and has been implicated in skin cancers. Photoaging is the premature aging or deep wrinkling of skin. Indoor tanning units utilize both forms of light waves to tan a person with a minimized risk of sunburn. Tanning outdoors does not give you this option because the sun omits every type of UV rays, so a person is more likely to burn. A person’s skin epidermis consists of two layers: The germinative layer and the horny layer. Another name for the germinative layer is the “living layer.” And another name for the horny layer is the “dead” layer. When exposed to ultraviolet light, melanocytes in the germinative layer produce melanin that is absorbed by surrounding cells. Melanin is a dark pigment found in the pigment-bearing cells of the skin, and melanocytes are epidermal cells capable of synthesizing melanin. This creates a protective barrier from ultraviolet light reaching deeper into the layers of the skin. The pale pink melanin granules are stored in the core of keratin cells. UVA darkens the melanin,

Melanoma is a malignant condition arising from melanocytes in the basal layer of the skin. Melanocytes are the cells that produce melanin, which gives skin its pigmentation and shields the deeper layers of skin from the damaging effects of ultraviolet radiation. When skin is exposed to ultraviolet radiation, melanocytes increase their production of melanin, which generates darker pigmentation of the skin. Ultraviolet radiation stimulates malignant changes within the melanocytes by mutating DNA, stimulating cutaneous growth factors, decreases immune defenses, and promotes species of melanin that cause DNA impairment and suppress apoptosis. The abnormalities caused by ultraviolet radiation in the melanocytes predispose it to

Melanoma is the most dangerous type of skin cancer. It develops when unrepaired DNA damage to your skin cells trigger genetic defects that lead you skin cells to multiply at a fast pace and form tumors. Melanoma can often resemble moles and some can come from previous moles. These melanoma moles can range in color from pink, red, brown, purple, white, blue and skin-colored, but more mostly seen as black or brown. It’s said that consumers who use indoor ultraviolent tanning devices are seven-four percent more likely to develop melanoma compared to someone who has never used a tanning bed before. Melanoma is usually caused from intense and over exposure to UV radiation. It has be estimated to kill around 10,000 individuals in the U.S. each year. The lifetime risk of melanoma is 1.5 times higher in males than in females. Melanoma is curable, if it is recognized early and

     Distinguishing melanoma may seem hard to do, but is not so once a person is informed on what they should be looking for. They may appear similar to moles, and may be blue or black in color. Though they will usually lack the symmetry and border regularity of a common mole, and may have variance in their coloring. Melanomas can either appear suddenly, or develop slowly near a preexisting mole. In rare cases, melanomas may form on top of previously formed moles or birthmarks, but will also come with the effects of pain, itching, or bleeding. These moles may begin to exhibit new and/or strange characteristics such as

If you notice a change in shape or color of a mole or mark on the skin, it's important to see a dermatologist. Just like any version of skin cancer, diagnosis is found from a skin biopsy. If you visit a dermatologist they will cut part of the mole off and or all of it, and send it to a lab to be tested. If the biopsy comes back positive for basal cell carcinoma, the dermatologist will pick the best treatment based off of the growths length, size, and the patient's health. If positive the surgeon will cut the cancerous tissue fully out depending on the size, and kemo may be needed if the disease is vastly developed. If the tumors are larger skin grafts will be necessary. After surgery you will have to check in with your family doctor to be checked for signs of the disease coming

Exposure to abnormally high frequencies of light can potentially alter the DNA of a cell and turn it cancerous, the resulting cancerous cells are known as skin cancer. The most common cause is ultraviolet light emitted by the sun although it has been known to be caused by tanning booths, unusually high levels of x-rays, exposure to some chemicals and in rare cases the abnormal genes that cause skin cancer can be inherited by children from their parents.

Melanoma is a rare and serious. It begins in the skin and can spread to other organs in the body.

Further, one third of all cancers diagnosed globally are classified as skin cancer. Each year, approximately 132,000 people are diagnosed with melanoma worldwide. (Skin Cancer, 2017). Although less common that other forms of skin cancer, melanoma is much more likely to metastasize, and therefore much more deadly. The researchers at Cancer Research UK state that the incidence of malignant melanoma has grown more rapidly over the last thirty years than any other form of cancer (Upton,

The third factor that plays a major role in causing skin cancer is the Ozone layer. It helps protect people from ultraviolet radiation. However, the ozone layer is shrinking and this is due to man-made products like sprays and combustion of cars that are emitted in the atmosphere. This process is allowing more ultraviolet penetration to the earth thus increasing risk of skin cancer (Bair, 1991, P. 367,368). Ultraviolet radiation are the chief causes for skin cancer because the UV radiation

Melanoma is a dangerous invasive cancer which starts in melanin producing cells (melanocytes) usually located at the bottom of the skins epidermal layer. Although certain individuals have a genetic propensity for melanoma, it is usually triggered by excessive UV exposure from sunlight or tanning beds (Mayo Clinic, 2016a). At early stages it is relatively easy to treat, however, recurrences are common. At later stages melanoma treatments are less effective since it tends to metastasize and spread easily through the lymphatic system (Mayo Clinic, 2016a).. The root cause of malignant melanoma is due to mutations in the p53 gene protein which invariably leads to further mutations.

According to the American Cancer Society, skin cancer is the most common cancer, accounting for about half of all cancers in the United States. More than 3 million cases of skin cancer will be diagnosed in the United States alone this year (Skin Cancer Foundation). Basal-cell carcinomas constitute approximately 90 percent of all non-melanoma skin cancers, making it the most common cancer in humans. Basal-cell carcinomas or BCCs are abnormal, uncontrolled growths or lesions that arise in the skin’s basal cells, which line the deepest layer of the epidermis. This type of cancer most often occurs in skin that is frequently exposed to sunlight or other ultraviolet radiation such as the face, ears, neck and limbs (Rubin et al.). As ultraviolet rays

C. Melanoma Skin Cancer is the most dangerous form of skin cancer, it kills one person per hour, these cancerous growths are most often caused by ultraviolet radiation from sunshine or tanning beds. These tumors originate in the pigment-producing melanocytes in the basal layer of the epidermis. Melanoma is caused mainly by intense, occasional UV exposure (frequently leading to sunburn), especially in those who are genetically predisposed to the disease. Often the first sign of melanoma is a change in the size, shape, color or feel of a mole.