Migraine Research Papers

but these painful, long lasting headaches can leave nasty, long term effects. My reasoning behind

Within the 1960’s a new form of drug was created and was said to be an essential pharmaceutical that should be in every doctor’s bag. This drug was called lysergic acid diethylamide, but is more commonly know as LSD. Albert Hofmann, as Swiss chemist, created this new drug in hopes that he might have found a profitable analeptic that could cure migraines. However, this was not the case. Hofmann decided to dose himself with the drug to see if it would help subdue headaches. He quickly discovered that this new

Migraine headaches are the third most prevalent illness in the world, and ranked as the sixth most disabling illness. Statistics show that only about fifty percent of people who suffer from chronic headaches know that they’re suffering from a migraine. 76% of people who suffer from migraines worry that they will suffer for the rest of their lives, and 37% of sufferers worried about their migraines between attacks. Studies found that approximately 12% of Americans suffer from migraines, and 40% of Americans could benefit from preventative therapies. Even though studies show that at least 40% of sufferers could benefit from preventative therapies, only one in five sufferers are currently using preventative therapies. Studies also show that over 25% of people who suffer from migraine attacks miss at least one working day over the past three months, and nine out of ten sufferers say that they cannot “function normally” during those days. At least 98 percent of migraine attack sufferers take medications for temporary headache relief, whether it be over the counter or prescription. Only 12% of sufferers take preventative medications as opposed to the 98% of sufferers taking medications for relief. Severe migraines are ranked in the highest of seven disability classes, along with psychosis, dementia, and quadriplegia, published by the World Health Organization. People who participated in a survey who admitted to a

Migraines contrary to old beliefs are not just bad headaches! Migraines are actually a neurological disease that affects 38 million people worldwide, according to the Migraine Research Foundation, 1 in 4 U.S households have at least one person who suffers from debilitating migraines living there. Although there is no cure for migraines, the vast majority of these victims use Excedrin Migraine or Advil Migraine to try to dull the sharp, throbbing pains they experience. These over the counter pain relievers may be very similar but they also have many differences.

On admission, Ms. Pilkey subjectively described her pain as being rather excruciating. There were times when she had to curl up into a ball due to pain during the week prior to admission. Her headaches felt like a “stabbing pick which penetrates her head” that is not localized to a particular region. The initiation of topiramate on July 31st 2015 has helped. The frequency, duration and degree of pain from chronic daily headaches had reduced considerably, allowing Heather to have a better quality of life. However, the degree of cognitive impairment, manifested in difficulty understanding commands and word finding have been more pronounced. In addition, she often forgot to take her morning dose of topiramate due to the cognitive deficits

Thor-ough history and physical examinations were found to be the main arguments, as effec-tive diagnosis and aetiology of neuropathic pain is required in order to treat signs and symptoms. The main point the author is presenting is that there is a substantial associa-tion between neuropathic pain and other clinical conditions, making it particularly chal-lenging to identify the epidemiology. The author’s outline that in order for appropriate clinical evaluation and treatment one must have understanding of the diverse range of mechanisms of pain management. A primary care approach to clinical assessments can be helpful in identifying appropriate treatments by ruling out these mechanisms. Evidence shows that safe and efficient treatment includes first-line therapy with antidepressant and anticonvulsant drugs, however these essentially only provide symptomatic

Sulmatriptan is a selective 5-HT1D agonist but also has actions act 5-HT1B receptors. Sulmatriptan does not cross the blood-brain barrier. The mechanism of action of drugs use in migraine are very little understood as they include such a wide variety in actions sunatirptuan and it congnars are currently 1st-pherorapy for a kid acute migraine in most patient they should not be use for patient at risk for pulmonary artery sunatriptan an order triptans are selective agonist for 5-HT1D and 5-HT1B receptors. These receptors types are found cerebral and meningeal vessels and moderate vasoconstrictron they are found on neurons and probably function as brbs inhibitior receptors the efficacies of all the triptan 5-HT agonist in migraine are equal to

In summary, Miss A came to seek medical attention with the onset of a scale of 8/10 Migraine headache of 2 days. After careful examining her and taking a complete history, Miss A is diagnosed with Migraine headache without aura. The NP is able to establish a treatment plan with Miss A’s involvement. The treatment plan includes: acute Migraine management and prophylaxis management. The acute Migraine management is proven to be effective for her as the evidence of pain relief: her headache was a scale of 2/10 after taking Sumatriptan combined with Naproxen. She also reports the nausea was improved after taking Metochlopromide and was able to consume normal oral intake. The prophylaxis intervention includes therapeutic teaching on healthy diet, effective scheduling on school and work, ensure plenty rest period, and relaxation

Migraines affect nearly 28 million people or 12% of the population in the United States. Migraines are typified by moderate to severe head pain. The head pain is often accompanied by one or more of the following; nausea, photophobia, phonophobia or vomiting. Migraines are considered a chronic neurological disorder. The incidence of migraine related nausea (MRN) is very high among migraneurs. Roughly 90% of patients experience MRN at one time or another. Roughly 50% of patients report experiencing MRN with high frequency (greater than half the time). MRN can hinder the efficacy of currently available migraine drugs in a number of ways. Many patients who experience MRN will delay or avoid taking oral or nasal migraine medication as it can further irritate their stomach. The GI upset associated with migraines can also affect absorption and thus limit systemic exposure to the drug. Researchers have been working diligently to find a solution to this problem.

Patients were instructed to keep a standardized diary of cluster headache symptoms starting at least two weeks before the administration of BOL-148. 30 μg of >99.2% purity BOL-148 was dissolved in distilled water and given once every 5 days to the patients for a total of 3 doses. The patients were monitored for between 3 and 4 hours after administration of experimental dose to monitor consciousness, thought disturbances, and vital signs. Patients were asked to continue completing headache diaries every day for at least one month or until they experienced an onset of new cluster headaches. All but one of the patients (S1) had

And although one of the side affects may be a headache, Botox has helped many people who have experienced these chronic

Looking at the migraine pathophysiology can help determine why migraines occur and what is happening inside the brain during them. Migraines were referred to as “vascular headaches” because it was initially thought that blood vessels were to blame for the pain. The blood vessels on the surface of the brain would dilate and with each heartbeat, the blood would surge through the blood vessel which would push the vessel against the skull which resulted in a throbbing pain. This idea has been thrown into doubt and new discoveries made. Cortical spreading depression, also known as CSD, is a wave of depolarization that slowly spreads from the back of the occipital lobe towards the front of the brain. This is then followed by the suppression of brain

Tension Type Headaches (TTH) are common in clinical practice. Tension type headaches lasts minutes to weeks. The pain is usually pressing or tightening in quality, mild to moderate in intensity, and bilateral in location, but does not exacerbate by the physical activity. Nausea and vomiting is usually absent, but photophobia or phonophobia can be present. The words tension and type underline its indefinite pathogenesis and indicates some kind of mental or muscular tension may play a causative role. Tension type headache is a common form of headache and most people with acute TTH never consult a doctor. They treat themselves with over the counter analgesic drugs and become frequent or chronic users of these drugs, thereby causing major health

Additionally, there is no specific cure for migraine headaches. In addition, the goal in treating migraines is to treat migraines symptoms. Also, migraines can be treated with amitriptyline or venlafaxine. Furthermore, a migraine can be treated with blood pressure medicines such as propanolol. Researchers have also proven that migraines can be treated with seizure medicines such as valproic acid. (http://www.sciencedaily.com/news). In addition, when I read that you can treat a migraine with seizure medications, I thought that research finding was interesting to be aware of. Also, researchers stated that you could treat a

Migraine headaches are the result of a disturbance in the neurochemistry of the central nervous system. They are relatively common, affecting three times as many women as men. Migraine sufferers typically report a definite pattern to their headaches, and they can report what stimuli bring them on. Most migraine sufferers experience their first attack before the age of 20. There is no single cause of migraines, but the tendency to get migraines does tend to run in families. When a migraine occurs, it means that something has altered several of the neurotransmitter-sensitive receptors located on the outside surface of the nerve cells (neurons) so that the nervous system is no longer able to constantly maintain the natural balance that the