Pathophysiology Of Diabetic Neuropathy And Diabetes

Diabetes is a disease in which the body is unable to properly use and store glucose. The glucose then backs up in the blood stream and causes a person’s blood sugar to rise to high. There are two types of Diabetes. Type 1 is referred to as Insulin Dependent Diabetes. In this type the body completely stops producing insulin. Insulin is the hormone that lets the body use the glucose found in foods for energy.

Diabetes is a chronic disease that affects how your body turns food into energy (sugar). Type 2 diabetes has reached epidemic proportions in the United States, and the statistics continue to grow with no change in site, and is a major cause of cardiovascular disease.

Diabetic Peripheral Neuropathy (DPN) is one of the most common microvascular complications in diabetes and can result in foot ulceration, ampuation and an impaired quality of life(Carrington AL, et al 2002,Boulton AJ,et al 2004). The reported prevalence of diabetic peripheral neuropathy ranges from 16% to as high as 66%2 and its prevelance is believed to increase with the duration of diabetes and poor glucose control.(Boulton AJ.et al 2000) It’s accounts for 50–75% of non-traumatic amputations in diabetic patients.(Holzer SE, et al 1998, Boulton AJM, 1998,Malay DS, et al 2006)

Type 2 diabetes (type 2 diabetes mellitus) is a long-term (chronic) disease that affects blood sugar (glucose) levels. Normally, a hormone (insulin) moves glucose from food into tissue cells, where glucose is used for energy. In type 2 diabetes, lack of insulin or lack of a normal response to insulin causes glucose to build up in the blood instead of going into tissue cells. As a result, high blood glucose levels develop, which can cause many complications.

Diabetes (Diabetes Mellitus) is an unremitting disease where in the glucose in the blood is too high. Blood glucose level, or commonly known as the ‘blood sugar level’, are normally regulated by the hormone insulin that is made by the pancreas. Diabetes takes place when a problem in the hormone happens and how the body works. There are different types of diabetes – Type 1, Type 2, Impaired Glucose Metabolism, Gestational Diabetes and the Secondary Diabetes, but the two main

Diabetes is a metabolic disease where an individual’s blood glucose level is higher than normal standards. Diabetes is a long term condition that causes not only primary issues related to the disease but secondary problems as well. Diabetes also known and referred to by healthcare professionals as diabetes mellitus, which is a phrase used to describe a group of metabolic diseases in which a person’s body does not produce insulin at all, or a person’s body does not use insulin properly, which is called insulin resistance. Type I Diabetes also known as juvenile diabetes is when the body does not produce insulin, approximately 10% of all diabetes cases are type I. Type 2 diabetes is when the body does not use insulin properly and approximately 90% of all documented cases worldwide is of this type. (American Diabetes Association, 2014) All types of diabetes can be treated, type I has no known cure however there have been some cases where

What is diabetes? First, let’s cover the basics of my subject diabetes. Diabetes is a disease when a person’s blood glucose levels are unstable. Type 2 diabetes make up 90% of diagnosesType 2 Diabetes occurs when a person’s body no longer uses it’s own insulin correctly You’ve probably seen the pills prescribed to diabetics’ commercials on TV, In Type I diabetes, a person’s pancreas can no longer produce insulin on its own,so to survive they have to inject insulin,there is no other way to get the insulin they need to live.

Diabetic neuropathy is a nerve disorders caused by diabetes. Symptoms include pain, tingling, or numbness, loss of feeling in hands, arms, feet, and legs. Nerve problems can occur in every organ system. Diabetic neuropathies appears more common in people who have problems controlling their blood glucose, those with high levels of blood fat, high blood pressure and obese (Porth, 2015). Metabolic factors include high blood glucose, abnormal blood fat levels, and low insulin levels. Neurovascular factors are associated to damage to the blood vessels that carry oxygen and nutrients to nerves (Porth, 2015). Autoimmune factors that cause inflammation in nerves. Mechanical injury to nerves, for example, carpal tunnel syndrome (Porth, 2015). Inherited

Diabetes is a chronic condition that occurs when the body can’t either properly produce or use the hormone insulin. When your cells in the pancreas that make insulin are destroyed, it means you have type1 diabetes. Type2 diabetes happens because the body can’t respond to insulin normally. Eating too much sugar can cause weight gain, and weight gain can increase a person's risk for developing type2 diabetes. Due to that, type2 diabetes is becoming more common.

Diabetes is a disease that cases blood glucose levels to rise higher than normal in the body. Type 2 diabetes is the most common form of diabetes when being compared to type 1diabetes. When blood sugars rises to levels higher than normal it is called hyperglycemia. Diabetes, type 2 can result in many different issues that affect the body. There are many complications that are linked with diabetes for example, higher risk

Management of diabetic neuropathy will reduce the symptoms of the pain and improve the quality of life of an individual. However, it important that clinicians are thorough in clinical evaluation of patients to be aware of the indirect warnings of disease process (Cox, DeGraauw, & Klein, 2016). One cannot design a treatment plan, until a complete history and physical examination are necessary. Armed with extensive information about diabetes, signs, complications, and cognizance to make appropriate therapeutic intervention then it can be anticipated that we can take account of any possibility of differential diagnosis, so as to efficiently classify the patient for treatment or to direct patients to the proper healthcare provider, thereby minimizing and preventing mortality and morbidity (Mathers, 2012, p. 216).

Diabetes affects virtually every aspect of the body and poorly controlled diabetes increases the risk for diabetes related complications. Patients diagnosed with mental illness are at an increased risk to develop diabetes complications as a result of poor self-care management (Green, Gazmarian, Rask, & Druss, 2010). Dickerson et al (2011) found that patients diagnosed with bipolar disorder tend to have a more sedentary life, poor dietary intake, be obese, smoke and have an increased risk for alcohol and illicit drug abuse. Each of these factors contribute to poor glycemic control, which contributes to the development of diabetic peripheral neuropathy. Up to 50% of patients diagnosed with diabetes have some form of diabetic neuropathy. Diabetic neuropathy presents in the form of sensory neuropathy, motor neuropathy or autonomic neuropathy. Sensory neuropathy may also be called polyneuropathy due to the number of different nerve centers affected by damage. Over time elevated glucose levels lead to extensive damage to the blood vessels that supply nerves to numerous sites in the body. Continued assault upon nerves can lead to permanent nerve damage, resulting in pain to affected areas and increased risk of injury, which can lead to amputation (Diabetes UK, n.d.).

     Diabetes is a chronic condition in which the body produces too little insulin (Type One Diabetes) or can’t use available insulin efficiently ( Type Two Diabetes). Insulin is a hormone vital to helping the body use digested food for growth and energy.

“Diabetic neuropathy begins as a generalized asymptomatic dysfunction of sensorimotor or autonomic peripheral nerve fibers and is by far the

Diabetes mellitus, commonly known as diabetes, is a chronic, lifelong condition that affects your body 's ability to use the energy found in food. There are