1. INTRODUCTION
1.1 Background Information
It was only after I found myself experiencing symptoms of persistent fatigue did I decide to go see a doctor. Having provided details about my fatigue, hair loss, dizziness and loss of focus, the doctor decided to order a blood test to determine the cause of these symptoms. After performing a complete blood count test (CBC), which is often used to measure the number of blood cells in a sample of blood (including red blood cells and hemoglobin, the iron-containing molecule in red blood cells that carries oxygen), results were reviewed and I was diagnosed with anemia, which was caused by an iron deficiency. This means that my stores of iron were too low to support red blood cell production.
Beef,
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This allows iron(II) to be oxidized to iron(III), hence the two reactants are permanganate (MnO4-) and Iron (Fe2+), and the products will be manganese (Mn2+) and iron (Fe3+). The two half-equations for the reaction can be seen below:
Fe2+ Fe3+ + e-
MnO4- + 8H+ +5e- Mn2+ + 4H2O
These combine and the overall redox reaction is described by the following chemical equation:
MnO4- + 8H+ + 5Fe2+ Mn2+ + 4H2O + 5Fe3+
Throughout this investigation compounds will be carefully measured so that their concentrations and volumes can be determined to a high degree of accuracy. This way I will titrate an iron solution with potassium permanganate until the endpoint —the point at which the solute at the flask (Fe2+) has reacted completely and no further titrant (MnO4-) should be added. This will be indicated by a change in colour, with the solution showing the first persisting faint pink colour.
Now some necessary calculations have to be made so that the experiment can proceed. Using the known concentration and volume of used MnO4- and the knowledge of the stoichiometry of the reaction, we can estimate the iron content after a multiplication of the moles of Fe2+ and its molar mass (55.845 g/mol).
Materials & Apparatus · 250 cm3 conical flask
· 250 cm3 volumetric flask
· 5 Fero-Gradumet iron
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Additionally, concentrated sulfuric acid is very corrosive to eyes and skin.
Safety googles, gloves and an apron should be worn for this experiment. Preparation of iron (II) solution: The mass of 5 iron tablets is measured by electronic balance. Using a mortar and pestle, the weighted tablets are crushed manually and turned into homogeneous powder. Ground material is transferred to a 250 cm3 glass beaker with 200cm3 of deionized water in it. The solution is stirred with glass rod. This solution is transferred to a 250cm3 conical flask that had been previously washed with deionized water. The solution is made up to the graduation mark with 50cm3 of 2.0M H2SO4. The conical flask is stoppered and inverted 10 times to ensure sufficient mixing. Water is sprayed around the glass surface to minimize chances of unwanted Fe residues.
Determining the concentration of iron Prior to the titration, all glassware is to be washed with deionised water. Burette and pippete respectively are rinsed with the solution they will contain to minimise error. Using a funnel, the burette is filled up with 0.1 M Potassium permanganate. Ensure that the part below the tap is filled prior to adjusting to
Fatigue: The growth and development of red blood cells in the bone marrow may be suppressed while having increase in the number of malignant plasma cells, which then cause low levels of red blood cells in the blood. This condition, know as anemia, can result in unusual fatigue or weakness.
Anemia is a medical condition defined as having low amounts of red blood cells, thus transporting low levels of oxygen in the blood. Common symptoms include fatigue, weakness, and shortness of breath. Causes for anemia vary, depending on the severity and duration of illness. Regular anemia can result with low levels of iron in the blood. (Mayo Clinic, 2014)
We realized my naturally tan complexion had slowly paled, another red flag. In February, I was once again eligible to donate. Everything was fine until the nurse tested my hemoglobin, which had at one time been close to the maximum level for donation. Now, I was at 12.4, 0.1 below the minimum measurement. Trying to hold back tears, I let the nurse try my other finger. 12.4. I was crushed. I left the donation center confused and determined to raise my level enough to donate. Two days later, I tried again and barely made the qualifications. Ecstatic, I donated and forgot all about it, assuming I had lacked iron in my diet for the month or something. About two weeks later, I received a letter from Red Cross. They told me my ferritin levels are below eight, I’m not allowed to donate for a year, and I needed to go to the doctor. I had no idea what ferritin was. After a lot of research, I discovered that it’s the protein in your cells that stores iron. A set of blood tests and a doctor’s visit later, I was told I have anemia. Anemia occurs when your blood lacks iron and therefore keeps your red blood cells from delivering oxygen throughout your body. All of a sudden, everything clicked into
Anemia is a disorder of the blood. It occurs when your body does not produce enough erythrocytes or red blood cells (RBCs). Without the erythrocytes oxygen can not be adequately delivered to the tissues and organs throughout the body. This will cause you to become weak and tired. A person may also experience headaches, skin pallor, and faintness. Your body may attempt to compensate for these symptoms by speeding up the heart rate and respiratory rate. This is the body’s attempt to return oxygen levels to normal(Thibodeau and Patton, 2005).
Iron Deficiency Anemia affects millions of individuals across the world. This disease strikes many more women than men and has harmful effects on all who suffer from this deficiency that causes oxygen-carrying capacity to decrease. The causes can vary amongst different groups, but the aggravating symptoms remain constant. Much of the research on Iron Deficiency Anemia concentrates on not only the treatment of this disease, but also the prevention of it. To attain a better understanding of how to treat this problem, one must clearly know what Iron Deficiency Anemia means, what causes this disease, the effects of it, and finally how to cure it.
mL cylinder to the beaker on the stir plate and empty it into the beaker. Place the pH probe in the beaker and record the pH in the data table. Drag the beaker to the red disposal bucket. Double-click the bottle of NaHCO3 to move it to the Stockroom counter. Repeat steps 5 and 6 for KNO3.
Part 1: Obtain some 0.200M Fe(NO3)3 solution and some 0.00020M KSCN solution. Starting from the first solution, pour and mix 8.0mL of Fe(NO3)3 solution and 2.0mL of KSCN solution into a test tube, where as the second solution has 7.0mL of Fe(NO3)3 solution and 3.0mL of KSCN solution. Continue this process until 5 test tubes have been filled. Pour
Iron deficiency anemia, one of the most common types of anemia, is a blood disorder where
Also known as normocytic anemia. This is the most frequent type of anemia most often happening to males over 85 years old. It is a common problem that occurs to men and women over 85 years old. Symptoms include and are caused by: a reduced production of normal-sized red blood cells even though presence of hemoglobin in the red blood cells is within the standard range; an increased production of HbS as is seen in sickle cell diseases; greater destruction and loss of red blood cells; an increase in plasma volume that is not compensated by anything else; a B2 (riboflavin) deficiency; and a B6 (pyridoxine) deficiency. (Brill & Baumgardner 2000).
From data table 3, Kf values range from 327 to 362, averaging out to be 345. [Fe3+] and [SCN-] initial concentrations were first calculated using Beer’s Law M1V=M2V2 dilution equation. Then [FeSCN2+] was calculated using the found concentration of [Fe3+] and [SCN-]. After that, [FeSCN2+]eq. was solved by (A eq.)/(A sd. ) [FeSCN2+]sd.
This information would be used in Part III to determine an unknown mixture with the results that were found in Part I. A singular drop of Pb(NO3)2 , Fe(NO3)3 , Ni(NO3)2 , AgNO3 , Ba(NO3)2 were added to the reagents: K2CrO4 , KSCN, NH4OH, DMG, HCl, H2SO4 inside of the glass spot plate. If a precipitate formed than the combination resulted in a change of color or appearance (results to these reactions are found in table 1.1). Part II included using the same procedure as done in Part III except this sample contained 1 mL of all five metal ions. This was meant to be a practice round to understand the different steps and procedures. Unfortunately, due to time concerns this trial was cut short at step 3.
* Anemia-related fatigue occurs when there is a decrease in red blood cells (RBCs). This happens when myeloma cells replace RBCs in the bone marrow.
I prepared a new ferrioxalate solution by adding 1g of into 25mL of distilled water in a 150mL beaker. Then, I added 1g of oxalic acid and placed it on the bottom shelf. 2. I cut out 4 pieces of paper circles with approximately 9cm in diameter. 3.
7. The initial and final volume along with the grams of the analyte was recorded on the data sheet and the amount of KMnO4 for each flask was calculated. Calculations and recordings of the mass percent of iron in the unknowns were finished.
through the duration of the entire experiment. Part 1 involves the synthesis of an iron (III) oxalate complex. The iron is first presented in its Fe2+ form, so it must first be oxidized to