preview

Pneumoccal And Influenza Vaccination Case Study

Decent Essays

Pneumococcal and influenza vaccination are among one of the measures that can reduce the risk of otitis media (4). The major aim of introduction of vaccine in immunization program is to prevent diseases caused by Streptococcus pneumoniae. This is because the effectiveness in the use of antibiotic and other drugs was reduced due to drug resistance strains. There are two types of vaccine recommended for effective prevention of pneumococcal diseases. These vaccines are pneumococcal conjugate and pneumococcal polysaccharide vaccine. Pneumococcal conjugate vaccine is approved for three classes of individuals: children younger than 2 years, children > 2 years to 64 years with medical indication and all adults 65 years and older. …show more content…

Before introduction of PCV-7 in the Netherlands, overall invasive pneumococcal disease (IPD) rates were 35 cases/100,000 children <2 years of age, of which 15 cases/100,000 children were meningitis (7). After PCV7 introduction, IPD caused by vaccine serotypes declined in all ages (8). Nevertheless, diseases caused by non-vaccine serotype increased (9). In May 2011, PCV10 replaced PCV7. It caused a decrease in PCV10 IPD incidence in PCV10-eligible children (10). In all age group, pneumococcal pneumonia and invasive pneumococcal disease hospitalization and death reduced in 2005-2006 season in United States (11). Irrespective of this large fall in IPD disease, a leading question is whether vaccination with PCV7 and PCV10 have an impact in reduction of non- invasive pneumococcal infection. A double blind randomized controlled study (12) showed that illness episodes in children greater than 1 month reduced by 7% among those vaccinated with 9-valent conjugate pneumococcal vaccine, where 85% of episodes were related to respiratory tract and 15,16 and 17% were observed in upper respiratory infection, lower respiratory tract infection and otitis media respectively in day care centers. Reduction of pneumococcal pneumoniae in younger and older adults was imputed to herd immunity. Most vaccination are …show more content…

Domain: All patients with non-invasive pneumococcal infection
Outcome: Non-invasive pneumococcal infection. Episodes are pneumonia (R81), acute bronchitis/bronchiolitis(R78), influenza(R80), sinusitis (R75) and otitis media (H71) from primary care visit.
Non-invasive pneumococcal disease = F (Pneumococcal Vaccine |confounders)
Confounders = Smoking, Low CD4 Cell count, Chronic Lung Disease such as COPD,

Get Access