Psoriasis The Integumentary is a vast organ system composed of exocrine glands, hair, nails, and the most commonly known organ, the skin. As a large system, it can be susceptible to many different types of diseases, one of these diseases are called Psoriasis. This affects a large portion of the Integumentary system, the skin. Psoriasis are considered to be a widespread, common and recurring disease that can be chronic at times. Psoriasis are defined by its appearance of light silver in color, flaky, rash on many parts of the Epidermis. Unfortunately, papulosquamous dermatitis comprise a group of dermatitis that have distinct multiplying
Both Psoriasis and Seborrheic dermatitis are common skin conditions. Scalp Psoriasis is a subtype of psoriasis that occurs on the hair-covered areas of the head. As Seborrheic Dermatitis typically affects the scalp as well, it may be difficult to tell it apart from Scalp Psoriasis. (1) The two diseases also share similar symptoms and treatments, which make them similar. For example, both of them cause redness of the skin, and it may cause visible red patches covered with silvery scales in some cases.(2) Another example, Seborrheic Dermatitis causeS greasy skin covered with flaky white or yellowish scales that may attach to the hair shaft. Likewise, Scalp Poriasis cause silver-white scales (layers of dead skin cells) that may attach to the
Brian is a 27-year-old male who suffers from plaque psoriasis (L40.0). His symptoms include red, itchy, flaking plaques located on his scalp, genitalia and legs with a BSA of 11%. Brain has tried and failed various treatments including triamcinolone and fluocinolone, both provided him with little to no relief. Brian is not a candidate for said biologics, because they can raise the risk of possibly fatal infections, Lymphoma, and other malignancies. I believe those risks of infection, malignancies are too high for Brian, in addition to both Humira, and Enbrel suppresses the immune system. Systemic medications are also too much of a risk for Brian because they have adverse side effects, which can also be extremely fatal and he is still of
As previously stated, Psoriasis is caused by a mistaken trigger in the Immune system. “Normally, T cells help protect the body against infection and disease.” (NIAMS, 2013) When the disorder triggers the immune system, it causes the T cells to activate and trigger other immune responses. This will develop the redness and scaling of the
Psoriasis is a condition that occurs on the skin from the cause of a build up of skin cells. When all of these cells get built up it forms dry, scaly patches on the skin that could be itchy or painful. Even though psoriasis affects the skin or integumentary system, it is also thought to be an immune system disorder. The reason medical professionals think this is because psoriasis is know to flare up or occur more frequently when you are fighting off a cold. It also flares up when you are under a lot of stress. The most common symptoms of psoriasis are rashes, dryness, flakiness, small bumps and redness of the skin, but it can also appear as dents on your nails, or even cause pain in your joints. The most common way to diagnose this condition
Psoriasis is a noncommunicable, chronic inflammatory skin disease. It is characterized by hyperproliferation of epidermal cells, erythematous patches covered with a distinctive scale and incomplete differentiation of keratinocytes (WHO, Menter 2008, Ashcroft 2000). Depending upon the percent body area affected, psoriasis can be classified as mild (less than 3%), moderate (3-10%) and severe (more than 10%) (Krueger et al 2000,). The worldwide prevalence of psoriasis is around 2% while in developed countries higher prevalence rates about 4.6% have been reported (Parisi et al 2013). The prevalence of the disease in adolescent and children ranges from 0.5% to 2% (Parisi et al, 2013; Tollefson et al., 2010; Fotiadou et. al., 2014). Out of the
Psoriasis is an irritating skin disease that primarily affects the scalp and extensor surfaces of the knees and elbows, though it can develop anywhere in the body. It is characterized by patches of abnormal skin that are typically red, itchy and scaly. It occurs when the reproduction of basal cells which are set at the bottom of several layers of cell and from which the skin growth increases dramatically. The upper layer of skin cannot shed the dead cells at the same rate and this scaly build-up occurs. The increase in basal cell production is believed to be caused by an imbalance of 2 natural chemical complexes called cAMP, which inhibits cell growth and cGMP which encourages cell growth. Proteins and toxins from bacterial and yeast metabolism
Psoriasis is without doubt one of the most long-established dermis issues and might occur on just about any a part of the physique, together with the penis. When a character has psoriasis, the dermis cell's life cycle is affected; it causes the cells to overproduce, making a construct-up on the surface of the skins
Psoriasis is a multifactorial disease that remains largely idiopathic. It is known to be autoimmune and inflammatory, with both genetic and environmental triggers and aggravators. [1,34] In fact 71% of children affected have a family history of psoriasis, as reported by Morris et al. [36]
Psoriasis is a dermatological condition that is chronic and progressive. It affects almost all surface of the body. It is associated with excessive growth of skin on the affected areas like the nails, palms, soles, elbows, knees, trunk, abdomen and back. There is no cure available as on date, but there are measures and medications that can help to decrease the vigorous symptoms which affect the quality of life which makes the patient feel negative and depressed. It is not contagious, many a times due to ignorance psoriasis patients are isolated for fear of getting infected by the family members. The dramatic representation of an uncontrolled psoriasis really affects the social life and employment prospects of the patient feeling the patient
We all want our skin to look beautiful. But, this is sometimes not always possible, especially if you are suffering from the effects of psoriasis. This skin condition is embarrassing and most people find themselves looking for clothing that will cover up their problem.
If you have an itchy rash on your feet, your first thought may be that you have athlete's foot. However, another cause could be psoriasis. Some people with psoriasis get it on their feet. It is commonly on the soles of the feet, but it can be on the toes or top of the feet too. Psoriasis is a bothersome skin condition. Your skin can crack, become scaly, itch, and burn. It becomes uncomfortable to wear shoes and you might even have trouble walking. If you have a rash or scaly lesions on your feet, you should see a podiatrist for a diagnosis. These are some treatments you might try if you suffer from psoriasis.
The paper I chose to provide a summary of was one that examined the use of stem cells in order to decrease psoriasis in mice. The researchers specifically used Mesenchymal stem cells (MSCs), which are those found in the umbilical cord blood. They are multipotent and therefore are able to differentiate into many different types of tissues. These stem cells, in particular, have an “inhibitory effects on innate and adaptive immune cells” (Lee). The hallmark of a diagnosis of Psoriasis is the visible skin irritation with red plaques on the epidermal level of the skin. The cause of the plaques is from cytokines and chemokines, which signal cells secrete proinflammatory responses encouraging a spike of immune cells in the region. The
Psoriasis is a disease that greatly affects a small amount of the population. It is estimated that about 3-5% percent of the population is diagnosed with psoriasis (Yu, 2016; Pg. 1). Psoriasis is defined as a chronic inflammatory skin disease (Lahousen et al, 2016; Pg. 78). The disease creates, in most cases, rough dry patches or lesions on the skin surface. Multiple sights on the body can be affected ranging from the scalp, face, and nails (Wade et al., 2016; Pg. 1). Though the disease largely results in physical symptoms, many patient’s health-related quality of life (HRQoL) is affected as well; health-related quality of life is an evaluation of how a person’s health affects aspects of life, mainly focusing on social, psychological and cognitive functions (Gonzalez et al., 2016; Pg. 2). This paper will examine multiple literatures in order to explore the connection between a patient’s health-related quality of life in regards to a diagnoses of psoriasis.
Males and females are equally affected by psoriasis vulgaris. Many studies indicate that age of onset is younger in females. Thus, one German study demonstrated an age of onset of 22 years in males and 16 years in females in early onset disease (Henseler and Christophers, 1985). However, results of studies are highly dependent on sampling techniques used and are variable in their results. There is no an approved evidence that the disease is phenotypically different between the sexes.
Psoriasis is a chronic inflammatory disease of the skin that results in proliferation and differentiation of keratinocytes and the infiltration of immune cells (1). The keratinized layers of dead skin do not slough-off as normal skin does; instead it builds up on the epidermis. The normal regulation of cell generation is hindered by the body. This disease affects over 1 – 2% of the general population and does not discriminate against any gender. There is no specific time that Psoriasis develops, but between the ages of 30 – 39 as well as 60