Rheumatoid Arthritis Research Paper

Rheumatoid arthritis is a systemic disease that affects whole systems of body particularly cardiovascular system, nerves, respiratory system (RACGP, 2009). The causes of rheumatoid arthritis are unknown but it is hereditary which assists to have a risk of rheumatoid arthritis by 50%-60% (RACGP, 2009).

Rheumatoid Arthritis(RA) is the most common type of autoimmune arthritis. RA is a progressive and debilitating musculoskeletal disorder that affects the joints symmetrically, causing a range of systemic effects. What it causes is still not well known; nevertheless, findings of new research points towards a believe that it is triggered by a defective immune system, which causes the release of inflammatory chemicals. These chemicals cause damage to cartilage and bone, usually affecting the wrists, the joints of the hand, including the knuckles, the middle joints of the fingers and feet. While this condition can affect any joints, besides, important body organs such as the eyes and the lungs can also be affected by the inflammation that occurs as a result of this chronic condition. Only in America 1.3 million of people are affected by this ailment, and 75 % of them are mainly women. Its onset usually occurs between fourth and sixth decades; however, RA can occur at any age("Diseases And

Weight can contribute to pain and discomfort with RA. Having excess weight on the joints can increase demands of the joints, causing swelling and decreased mobility. Slow, consistent weight loss, from dietary lifestyle changes is the most effective method of weight management. Resting for short periods of time when joints are swollen will reduce swelling, while increase in exercise helps build muscle strength, allowing for increased endurance. These subtle changes can promote an increase in positive attitude, reduced pain, overall better sleep patterns and management of weight. They also open communication for family participation with a loved

The type of joint that is chronically affected is the synovial joint. The bones that are at a synovial joint are covered by articular cartilage; which reduces friction and absorbs shock. The space between the articulating bones is

affected joints and later spreads to the joint capsule, the adjoining tendons, and the joint

Arthritis is the general term for the group of conditions that damage the joints and result in pain and stiffness in one or more of the body's joints. The most common forms are Osteoarthritis (brittle cartilage), Rheumatoid Arthritis (where the body's immune system attacks the joints), Gout (Created by a build-up of Uric Acid) and Ankylosing Spondylitis (Pain and stiffness in the lower part of the spine).

Thus, RA is a disease that affects the joints. It embodied by a flare up and remission. Although, this disease often occur in more than one joint and can affect any joint in the body. People with this disease may physically exhaust or fatigued experience fevers. Furthermore, RA is by far the most serious,

Rheumatoid Arthritis is a systemic chronic inflammatory disease of the joints. (Kobayashi, Momohara, Kamatani, & Okamoto, 2008, p. 4456) The term ‘chronic' refers to a disease being long term, and the term ‘inflammatory' means a sudden response to tissue in the body being injured.

Chronic inflammation from RA leads to loss of bone density, not only around the joints, but throughout the chronic inflammation from RA leads to loss of bone density, not only around the joints, but throughout the body, leading to thin, and brittle

Rheumatoid arthritis is a condition that affects about 1.3 million people in America. It causes pain and swelling around the joints. Other rheumatoid arthritis symptoms include fatigue, tenderness and weakness in the joints. There are a number of rheumatoid arthritis treatments available. The goal of treatment is to control the condition and improve a patient's quality of life.

There are hundreds of thousands of persons all over the place the world who whinge of joint discomfort. As everyone knows, joint ache can arise in one or even multiple joints in our physique. Inflammation of joints may additionally lead to suffering. Rheumatoid arthritis, which is an auto-immune sickness, is one of the fundamental explanations of joint discomfort.

Rheumatoid arthritis (RA) and atherosclerosis are two inflammatory diseases strictly linked; in fact, although joint involvement is the prototypical feature of RA, atherosclerotic cardiovascular diseases (CVDs) are the major cause of mortality and morbidity in these patients (Meune et al., 2010).

In addition to the discussion I would like to briefly explain the pathophysiology of RA. The interaction of genetic risk factors, environment and the immune systems are the main pathogens in RA. Regardless of the initial factors, RA progresses, when an amino acid required for protein synthesis is converted from arginine to citrulline (called citrullination), which alters the structure and function of the proteins. The body's immune system does not recognise these citrullinated proteins as self, and so begins to attack the immune system and occurs persistent inflammation of the synovium and bone destruction. Ongoing damage in the joint causes persistent inflammation and generates large amounts of inflammatory cytokines and growth factors. Circulation of high levels of these pro-inflammatory mediators causes the synovial joint inflammation (Casey 2015).

Normal wear and tear causes the most diagnosed form of arthritis, Osteoarthritis, otherwise identified as OA. A disease, injury or being overweight can worsen the natural breakdown of cartilage tissue. Another prevalent form of arthritis, Rheumatoid arthritis, otherwise identified as RA, is an autoimmune disorder. RA occurs when your body’s immune system invades the tissues of the body. These attacks affect the synovium, a delicate tissue in joints that produces a fluid that nourishes the cartilage and lubricates the joints. Doctors are still not certain of the cause of RA, but there is scientific evidence that hormones, environmental factors and genes are to blame. A patient's risk of developing arthritis may be higher if the patient has a family history of the disease. While different forms of the disease have different causes, they can all be equally

Rheumatoid arthritis (RA) is a very common disease associated with aging, which affects the mobility of an individual. RA is a disabling disease, which makes an individual cannot perform his/her daily tasks and exercises which is vital to our health. Patients who suffer from RA have high risk to have cardiovascular diseases (CVD) such as myocardial infarction and cardiac death than those without RA. Early detection of the RA, and the possibility to have CVD in the later period is a must to give medications and physical motor interventions.