Schizophrenia: Its Aetiology Essay

The biological explanation of schizophrenia also claims that the disorder can be inherited. The more common the disorder is among the biological relatives and the closer the degree of genetic relatedness increases the risk of the child developing schizophrenia. Gottesman’s research (1991) found a genetic link with schizophrenia when looking at children and their relatives. The research discovered that children with two schizophrenic parents have a concordance rate of 46% compared to children who just have one schizophrenic parent to children who have a concordance rate of 13% and siblings just 9%. The genetic theory of schizophrenia also suggests that monozygotic twins (twins who a genetically identical) should have a higher concordance rate of schizophrenia than dizygotic twins (twins who are not genetically identical) because they have a closer degree of genetic relatedness.

Genetics play a role in the development of schizophrenia. When looking closer at the brain chemistry between a person with schizophrenia and a person with out schizophrenia there are

.(3) Schizophrenia is often present in familial clusters. Monozygotic twins have an even slightly higher concordance rate. It has been found through studies that adoptive parents do not have any effect upon children in relation to developing the disease, which is also another strong biological marker. The risk factor of children with parents suffering from the disease rises from one percent to twelve percent . Another finding that backs up the biological basis claim is that lower levels of platelet monomania oxidase B are found in people suffering from chronic schizophrenia. Higher levels in the cerebral spinal fluid of these monoamine metabolites, HVA, and 5HIAA are found in people with a family history of schizophrenia as opposed to people without the genetic predisposition afflicted with the disease. .(4) These varying levels result in varying biochemical changes that are predetermined and passed through families.

Schizophrenia is a psychotic disorder characterized by distorted thinking, impaired emotional responses, poor interpersonal skills and a distortion of reality. It is the most common of psychotic disorders that, in most countries around the world, affects around 1 per cent of the population. In terms of explanations for the disorder, two central types of explanations arise – psychological explanations and biological explanations. Whereas psychological explanations tend to focus on cognitive, emotional and environmental factors that may cause the disorder, biological explanations tend to focus on genetic, biochemical and neuro-anatomical factors as the cause of the

Over the last few decades Schizophrenia has become embedded in mainstream vernacular as any behavior or emotional response that is out of touch with reality. However even with its popularity heightened through movies and headline news stories, schizophrenia is still one of the most enigmatic and least understood disorders of the brain. With current research focused on the role of neurobiology and functioning on a cellular level, investigative analysis has merited new innovations towards its source, however a single organic cause for the disorder still eludes scientists. Although the foundation of the affliction is still unknown, its effects are well documented and over the next few pages will show the changes in the brain as the disease

The risk is even greater for those relatives who are genetically similar to the schizophrenic. This theory poses important debates however. If schizophrenia is caused by simple genetics, identical twins should both be affected by schizophrenia if one twin has been diagnosed. It is rare to find a majority of identical twins affected. Studies have found there to be a weak genetic link to schizophrenia. A recent study of high-risk children found there to be little proof of a genetic link.

In this week’s readings chapter twelve is about schizophrenia. Schizophrenia is a psychotic disorder in which personal, social, and occupational functioning deteriorate as a result of strange perceptions, unusual emotions, and motor abnormalities. This disorder is very interesting, but also kind of scary to me. They literally end up in their own world, losing contact with reality. With that, they also experience hallucinations or delusions, which can cause them to do abnormal, possibly dangerous actions. These symptoms must last six months or more before the person can be diagnosed with schizophrenia. It will affect 1 out of 100 people in the world during ones lifetime. This disorder, unlike many others, is just as common among men and women,

This paper defines schizophrenia from a biological and psychological perspective and also provides treatment to help combat symptoms of schizophrenia. This paper has three important contributions. First, by defining and expanding on schizophrenia from a biological perspective, I can identify the nature related predispositions. After expanding from a biological approach, secondly, I will analyze schizophrenia from a psychological aspect by determining if there is any environment or nurturing externals that can result to schizophrenia. Lastly, I will provide treatment details and also reveal early signs to schizophrenia. This paper is important because schizophrenia is an epic mental disease and it is crucially important to bring awareness to the public of how we can limit the illness. It is unclear whether schizophrenia have only a biological background or psychological background, but what was discovered is that both contribute to schizophrenia. Positive and negative treatment can be combatted undergoing pharmaceutical and psychotherapy,

can put the baby at a higher risk for developing schizophrenia in later life. Also high

It has been widely accepted that schizophrenia has a genetic component, with the relative lifetime risk of schizophrenia being reported at around 0.3-0.7% (McGath et al, 2008) although some studies have shown this to be much higher at around 3.5% (Pedersen et al, 2014). Studies have shown the risk of relatives developing schizophrenia is correlated with the percentage of shared genes (Tsuang, 2000). Twin studies have been utilised to reveal a genetic component, as monozygotic (MZ) twins share 100% of their genes, while dizygotic (DZ) share 50% of their genes, therefore a higher percentage risk of development should be found within MZ twins. Studies have indeed revealed an increased risk of developing the disorder in MZ twins (48%) than in

Schizophrenia is a life-long disorder that affects about one percent of the population (Mueser & McGurk, 2004). The cause of this mental illness is still unclear. Studies have suggested that Schizophrenia does not arise from one factor but from a combination of genetic, environmental, and social factors (Liddle, 1987). People diagnosed with Schizophrenia struggle to deal with a multitude of symptoms that make it difficult to function (Mueser & McGurk, 2004). Antipsychotic medications are a popular treatment of the symptoms of Schizophrenia (Mueser & McGurk, 2004). Research is constantly being done to develop these medications to enhance the quality of life of those diagnosed with Schizophrenia.

Researchers favouring the biological explanation look at genetic factors, brain structure and biochemical explanations. Many researchers would suggest that the debate over whether schizophrenia is passed down through genetics is no longer a

One out of ten children of a schizophrenic parent will develop schizophrenia. The risk of 10% is greater then frequency of schizophrenia in the general population which is about 1% which would mean that schizophrenia is more likely to develop is some families than others most children of schizophrenic parents are completely normal. The most interesting investigation that is still going on that remains a mystery of schizophrenia is that genes alone do not explain who gets ill. Example of this is twins as all there genes are in common but if one of the identical twins has schizophrenia the other twin has the highest risk of developing schizophrenia. About 40% of twins of a schizophrenic live completely normal lives without disease.

Conclusions / Results: Conclusions suggest that the nature vs nurture dichotomy may not be as relevant as looking at the interaction between these two forces. It was discovered that while one’s genetic heritage creates a predisposition towards schizophrenia, other factors such as the home environment, the parental environment, dietary factors and others may determine whether the disease is manifested.

Schizophrenia is a mental illness that is diagnosed in 0.5%-1% of the population in their lifetime (van Os et al, 2010). Its literal translation is ‘split-brain’, though it does not refer to multiple personality disorder, but rather a split from reality characterized by its disturbed perceptions, disorganized thinking and inappropriate emotions (Myers, 2010). Much research has been carried out to gain a better understanding of the causes of this serious disorder. A popular theory is the diathesis-stress model. This theory of schizophrenia proposes that stress can elicit a pre-existing vulnerability to the disorder (Jones & Fernyhough, 2007). This model focuses on the interaction between genetic heritability of the disorder, and the environments interaction