Sickle Cell Anemia And The Middle East

Now that the disease is more clearly defined, we must ask, why did this illness come about? This is one of the most interesting facts about Sickle Cell. Since the trait originated in countries that were ravaged by malaria, it could be said that this trait evolved to fight the deadly mosquito-spread disease. "People with sickle trait were more likely to survive malaria outbreaks in Africa than those with normal hemoglobin, it is

Sickle cell anemia is a hereditary disorder that mostly affects people of African ancestry, but also occurs in other ethnic groups, including people who are of Mediterranean and Middle Eastern descent. More than 70,000 Americans have sickle cell anemia. And about 2 million Americans - and one in 12 African Americans - have sickle cell trait (this means they carry one gene for the disease, but do not have the disease itself).

Sickle cell disease is a disease that is most prevalent in people of African descent along with people of Mediterranean and Middle Eastern origin. This disease is known to affect about 70, 000 Americans and about 2 million people carry the trait (meaning that, they carry a single gene mutation).

It has always been assumed that genetics and lifestyle play a major role in the presence of health disparities and health care issue that affects African-Americans. This paper provides a historical background to a key disease more prevalent in the African American community, Sickle Cell Anemia, the history behind the disease, genetic mechanisms that influences once probability of inheritance and in-depth treatment on how to manage, prevent and sustain a healthy lifestyle when dealing with sickle cell anemia. Sickle cell anemia is a hereditary disease that alters important aspects of the body physiologically and can be inherited via genes. Sickle cell disease (SCD) was first identified in 1910 and has existed in the continent of Africa for five

In conclusion, sickle cell anemia and the sickle cell trait are more common in African-Americans and people who live in places where malaria is common. Individuals with the trait seem to live normal and healthy lives, however individuals who have the trait and experience high altitudes or vigorous exercise tend to feel unwell because of the lack of oxygen getting into the cells causing them to sickle. In addition, the sickling of the cells can be reversible to a certain extent in people with the trait, however people who have sickle cell anemia the sickling of the cells is irreversible due to the severity of the disease.

Sickle cell disease (SCD) occurs in 1 out of every 365 African American births compared to 1 out of 16,000 Hispanic-American births (1). SCD is a group of red blood cell disorders in which patients have a sickle or moon-shaped red blood cell due to an abnormal S hemoglobin. While sickle cell disease is relatively rare in American births, this is an alarming statistic among people of Sub-Saharan (west and central) African descent. An interesting fact is that SCD occurs more often among people from parts of the world where malaria is or was common, such as Sub-Saharan Africa (1). In addition, it is believed that people who carry the sickle cell trait are less likely to have

Sickle cell anemia affects a wide range of demographics, from young to old. However, there are specific groups of people who are likely more prone to this disease than any other group. This disease affects millions of people worldwide regardless of age, but it is particularly common amongst those who derive from specific regions of the world. Sickle cell anemia is most common in those whose ancestors are derived from the sub-Saharan region of Africa. Furthermore, other regions that are known to have a high number of people containing sickle cell anemia are from Mediterranean countries, the Arabian Peninsula, and Spanish-speaking regions as well ("Who Is at Risk for Sickle Cell Anemia?"). This disease originated from the sub-Saharan region of Africa, and later migrated to other areas through the spreading of other diseases such as malaria. This is due to the fact that sickle cell disease occurs habitually in areas that are prone to diseases such as malaria. Although this disease can affect anyone, the highest cases of sickle cell anemia were found in African-Americans than in any other race. In the United States, sickle cell disease affects about 70,000 to 100,000 Americans ("Who Is at Risk for Sickle Cell Anemia?"). The statistics show that 1 out of every 500 births is affected by sickle cell disease for African-Americans. For the Hispanics, 1 out of every 36,000 births is prone to sickle cell disease ("Who Is at Risk for Sickle Cell Anemia?"). The age ranges for which a

Sickle cell disease is an inherited form of anemia. This means both parents must pass on the defective gene for a child to be affected. The gene is more common in families that come from Saudi Arabia, Africa, Mediterranean countries, India, the Caribbean islands, and North, South, and Central America of African descent.

Sickle cell anemia is more common in sub-Saharan regions of Africa, where malaria is prevalent, than it is in regions where malaria is not common. This is because being heterozygous for sickle cell anemia in malaria-prone regions carries a fitness.

I chose to research sickle cell anemia in public health because I wanted to see how a disease can affect its community. I also chose sickle cell anemia because it is a disease very close to me, my whole family has the trait and my two youngest brothers have the disease. More of my family and individuals in Africa are getting sickle cell anemia and I believe it is because they are not tested and or educated about it. Sickle Cell Anemia is diagnosed at birth. It is diagnosed by a simple blood test to see whether the patient was sickle hemoglobin. In the United States, all states make testing mandatory for all newborn babies. This is not the case in African countries. They do not have the funds to do screenings in the first place which is very

Sickle cell anemia is the most common disease among African Mediterranean dissent; sickle cell anemia affects millions of people worldwide. There are 5 different types of Sickle Cell Disease which are Sickle Cell Anemia, Sickle-Hemoglobin C Disease, Sickle Beta Thalassemia Disease, Sickle-Hemoglobin D Disease, and Sickle-Hemoglobin O Disease. Sickle Cell Anemia is when a child inherits the Sickle Cell Disease gene from both parents in which they may gain the symptoms of Sickle Cell Disease, Sickle Cell. Anemia is when the blood has a low number of normal red blood cells in the body. People with Sickle-Hemoglobin C Disease have a somewhat different replacement of the Sickle Cell Anemia gene, there may be comparable symptoms but there are

Thousands of years ago, a genetic mutation occurred in people from the Mediterranean basin, India, Africa, and the Middle East. As the Malaria Epidemic attacked people of these countries, carriers of the defective hemoglobin gene survived. Carrying one defective gene means that a person has a sickle cell trait. Two parents with the trait will produce a child with sickle cell anemia. People of these countries migrated and spread to other areas. In the Western Hemisphere, where malaria is not much of a problem, having the abnormal hemoglobin gene has lost its advantage. Any child born from parents that each has the trait will be born with the disease.

Sickle cell anemia is an anemia that is inherited and mostly affects people whose heritage can be traced back to places where malaria was prevalent. There are approximately 100,000 Americans that have the disease and many more with the trait. Several of my family members are afflicted by this medical condition that causes red blood cells to take on an irregular shape.

Sickle cell disease is considered to be one of the most common monogenic disorder globally. [1] Recent studies suggested that between 300.00- 400.00 new born with heamoglobinopathies each year in the developing countries .[2] it was reported that about 5 % of the world population are carriers for heamoglobinopathies (2.3 for sickle cell disease and 2.9% for thalassemias ). [3, 4] Heamoglobinopathies is one of the world’s major health problem with high mortality rate.[5] Several epidemiological studies show that Saudi Arabia has a relatively high prevalence of hereditary heamoglobinopathies .

Sickle cell disease is a group of inherited blood disorders that affects the red blood cells, specifically the hemoglobin. This disease is very interesting because it actually is said to have protective advantages against malaria in the traits heterozygous form. Some scientists, along with students at Kenyon college, claim that the sickle cell trait has evolved or has been naturally selected because it provides vital protection from malaria (Camperchioli). This is mainly backed by the fact that the sickle cell trait is most commonly found in areas where malaria is predominant. Sickle cell disease is a leading cause of death for children in Africa and has begun to spread all over the world, which is why it is important to understand how