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Symptoms And Treatment Of Systemic Lupus Erythematosus

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PSYCHOSIS IN SYSTEMIC LUPUS ERYTHEMATOSUS: A REVIEW
Abstract

Key words – Lupus, Psychosis, SLE, NP SLE, steroids, reversible

INTRODUCTION
Systemic lupus erythematosus (SLE) is a chronic inflammatory and autoimmune disease of multifactorial etiology that can affect many organs and systems (Sato, 2002).
The studies show a higher prevalence in women (approximately 90% of cases), especially during childbearing years, i.e. between 15 and 45 years of age; more common in women of black ethnicity than in Caucasian ones at a ratio of 3:1 , but it can occur in all ethnic groups and geographic regions (Bonfá, 2011).
The central nervous system is often affected by this disease, causing neurological and/or psychiatric symptoms. Psychiatric syndromes in patients with SLE include a variety of psychiatric findings causing chronic disabilities (Jarpa, 2011).
SLE may cause a wide range of neurological and psychiatric symptoms including those due to central, peripheral and autonomic nervous system and different psychiatric syndromes. In 1999, the ACR developed a standardized nomenclature system for the NP syndromes of SLE for the purposes of classification and reporting (The American College of Rheumatology, 1997; 1999). It distinguishes three subsets of syndromes: psychiatric disorders, cognitive deficits and acute confusional states; neurological syndromes of the CNS and neurological syndromes of the peripheral nervous system (The American College of Rheumatology, 1997; 1999). Anxiety,

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