Organism
Syphilis is a sexually transmitted disease caused by Treponema pallidum. T. pallidum has an oddly small genome and lacks genes that encode numerous metabolic functions and classical virulence factors. T. pallidum is vastly infectious and lasts for decades in the untreated host. Early syphilis lesions result from the host's immune response to the treponemes. Treponema pallidum is a spirochetal bacterium often times are found growing in clusters. This pathogen has a protoplasmic cylinder bound by a cytoplasmic membrane, a thin layer of peptidoglycan, and an outer membrane devoid of transmembrane proteins. T. pallidum are spiral shaped, has rapid rotation about its axis, and two to three flagella at each end which allows a corkscrew like motility. It is microaerophilic and glucose-dependent; without glucose, oxygen harms motility. T. pallidum contains extremely small prokaryotic genomes and is accountable for the sexually transmitted disease, syphilis.
Transmission
Syphilis is an extremely contagious disease spread predominantly by sexual activity. Infrequently, the disease can be passed to another person
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The chancre typically progresses in the genital area. It may also grow on the tongue, lips or rectum if the area has been exposed to a syphilis chancre on another person during oral or anal sexual contact. The chancre can appear after the exposure at any time from 10 days to three months. The chancre heals in one to five weeks. If left untreated, syphilis will progress into a second stage called secondary syphilis. In this stage the bacteria that causes syphilis spread throughout the body. Symptoms start to appear after about six weeks after the chancre has resolved and include flu-like symptoms. These include sore throat, fever, weight loss, fatigue, swollen glands and headache. Other symptoms include hair loss, skin rashes, and a rash around the
I thought someone could get syphilis by contacting a surface that an infected person touched. Syphilis is almost always transmitted by unprotected vaginal, oral, anal sexual activity, or from mother to newborn during delivery. It is usually transmitted when open lesions on an infected person come into contact with the mucous membranes or skin abrasions of the partner’s body during sexual activity. It may also be contracted by touching an infectious chancre. In the primary stage of syphilis, a hard, round, ulcer-like lesion appears at the site of infection two to four weeks after contact. A few months later, the secondary stage begins. A skin rash develops that darken after a while and burst, oozing a discharge. The spirochetes continue to multiply and burro into the circulatory system, central nervous system, and bones and may lie dormant for decades. Lastly, in the tertiary stage, large ulcers may form on the skin, liver, digestive organs, muscle tissue, lungs, or other organs which can be
Syphilis is a rare sexually transmitted disease that causes serious health problems and complications if left untreated. This disease has stages and many symptoms. Both genders can contract it, but it can be cured and certainly prevented.
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The second stage of the disease is called the secondary syphilis, which begins about two to six weeks after the sores have healed.
Prior to 1932 information concerning the origin, conception, development, and the complications of untreated syphilis was known to medical science. The one element left to be known about this disease was a cure. By this time, scientist were well aware of the fact that syphilis was a highly contagious disease caused by treponema pallidum, a microscopic organism resembling a corkscrew. The disease may be acquired, meaning passed from person-to-person either during sexual intercourse or mixing of bodily fluids, or congenital meaning obtained through birth. The disease progresses in three stages: primary, secondary, and tertiary. The
Within a fourteen-year period, two studies in different parts of the world emerged that hoped to study the disease of syphilis. Here in the United States, Tuskegee, Alabama emerged as the starting point of one of these studies, in which Public Health Services’ physicians and officers studied the deadly effects of Syphilis on African American Males. When penicillin emerged in 1943 as the main treatment, this study denied their African American test subjects the opportunity to be treated, but rather continued their study, hoping to advance the current knowledge on the effects that syphilis has on a person if it goes untreated. Farther south, within the country of Guatemala, Public Health Services hoped again to study syphilis, but with a different focus. Rather than study the effects of untreated syphilis, Public Health Services worked to study various other chemicals that could be used to prevent and contain the spread syphilis, in addition studying certain doses of penicillin and their ability to treat the disease. To do this, Public Health officials and physicians purposefully infected various prisoners, people in mental hospitals, soldiers, and prostitutes. When looking at both of these studies, various ethical issues and dilemmas are present. By using two popular ethical schools of thought: utilitarianism and Kantianism, the ethical justification or justification of these studies will be explored. When discussing both the Guatemala and Tuskegee Syphilis studies,
From a sociological perspective, I do not think that hypothesis, “The rate of progression of Syphilis may differ by race when comparing African American males to Whites” is valid as is. Race is a social construct, however the experiences that which we go through because of race is very real. That leads me to believe the hypothesis could be valuable if it were framed differently. Because of environmental factors, cultural factors, and health disparites, certain races may be at risk for a particular disease than others. I feel that maybe if the hypothesis would have been framed as “The rate of progression of Syphilis may differ by race when comparing African American males who have (certain health problem) to Whites males who have (certain health problem)” it could have been valid. However, these men would have had to receive the same exact treatments and likely be from the same SES.
exposure, but they can take up to 30 days to develop. Gonorrhea symptoms in women include:
The syphilis bacteria colonizes in sores that are located on the external genitalia, and is passed from person
Syphilis has been referred to as ‘the great imitator’ due to the wide range of symptoms, most of which other disease also have. The primary symptoms are red painless sores, this kind of sore is a chancre. After a few weeks the chancre may disappear, but the disease doesn’t. If left untreated secondary syphilis begins, a rash may appear along with flu-like symptoms.
In 1932, the United States Public Health Service initiated a research study to determine the natural progression of untreated syphilis in African-American males in Macon County, Alabama. This experiment which lasted from 1932 to 1972 comprised of 412 men with untreated syphilis and 204 uninfected men who served as the controls. This study of “untreated syphilis in the Negro male,” is a tragic, nontherapeutic experiment in research which has violated multiple ethical principles and human rights.
Syphilis is spread from sexual activity. Symptoms of syphilis include; fever, sores, sore throat, and patchy hair loss. If left untreated for 10-30 years, syphilis can result in death. Doctors test for syphilis by testing your blood, or liquid from a sore. Syphilis can be treated and cured by taking certain antibiotics, but treatment may not undo any damage that has already been done. To prevent contracting syphilis stay with a partner who has been tested for syphilis and does not have syphilis. In the United States about 5 out of 100,000 people have
The first indication this disease gives us starts with sexual contact with another human being. Syphilis can be transmitted by the blood in a woman’s incubation period; which the period over where the eggs, cells and further more are incubated.
Syphilis is a bacterial STD caused by the Treponema pallidum bacteria. Syphilis is transmitted “through direct contact with a syphilis sore (“STD Facts-Syphilis” 2010).” The contagious sores can be chancre sores, which occur in the
The parasite is passed from an infected individual to a uninfected individual during sex. In ladies, the most ordinarily tainted piece of the body is the lower genital tract (vulva, vagina, or urethra), and in men, the most common contaminated body part is within the penis (urethra). During sex, the parasite is normally transmitted from a penis to a vagina, or from a vagina to a penis, however it can likewise