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Systemic Lupus Research Paper

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Systemic lupus erythematosus (SLE) also referred to lupus dates back to the middle ages and has made an explosion in the past 60 years. Even though more than 1.5 million Americans have lupus and 90% of lupus sufferers are women, between the ages of 15 to 44 (Lupus Research Institute), there is little awareness about the disease. 72% of Americans aged 18-34 have either not heard of the disease or know nothing about it (Medical News Today). However, researchers continue on working to have a better understanding of SLE factors, pathophysiology, current treatment and new prospects for treatment.
Anyone can get Lupus but women of color are two or three times more at risk for lupus than Caucasians (Lupus Research Institute), being Hispanic myself …show more content…

We are completely aware about certain diseases such as Cancer and Diabetes but yet we rarely see any type of public service announcement providing information about lupus. I am interested in finding out more information about lupus dealing with testing, treatment and pain management so then I can educate people about it. Normally our body produces antibodies to protect against foreign antigens such as viruses and bacteria, lupus is unable to distinguish it will attack the antigens but also the healthy tissue. This will cause swelling, pain and tissue damage to joints, skin, kidney the heart and lungs. The cause of lupus is still unknown but some contributing factors are hormones, genetics, environment and medication. There is no cure for lupus only treatment for the symptoms caused by lupus.
In the journal, A Review of Systemic Lupus Erythematosus and Current Treatment Options, focus on the clinical presentation of systemic lupus erythematosus treatment options from pharmacological and …show more content…

Both medical journals provide similar information about SLE dealing with genetic influence, hormones, cytokines and similar treatment. Only difference is Mechanisms of Disease Systemic Lupus Erythematosus gives information about environmental influence and A Review of Systemic Lupus Erythematosus and Current Treatment Options journal has no evidence to support any environmental influence. It gives details about the new medication, Belimumab, which was approved by Food and Drug Administration (FDA). The results are small but significant beneficial with the blockade of B-lymphocyte stimulator with an anti-BLyS antibody (Tsokos, 2011). Another new treatment option is small molecule inhibitors of kinases such as Syk and CaMK4 that are showed in the immune cells of patients with SLE (Tsokos,

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