Testosterone Replacement Therapy Research Paper

“He amassed great wealth for Egypt. As a great ruler and brilliant general.” (ancient-egypt-online.com) Some may know him for any of his great and noble acts but to most he is known for providing gigantic peace throughout Egypt also known as, the golden age! But we won't just be exploring just how great the deeds were that he had accomplished. We will also be exploring how he never lost a battle, or how he was a fair captor.

Testosterone belongs to a class of male hormones called androgens that is vital for sexual and reproductive development. The National Institutes of Health regards “testosterone as the most important male hormone”(Rettner). Although the primary role of testosterone directly relates to males, women also produce testosterone at lower levels. Women’s total levels are about a “tenth to a twentieth of men’s levels”(Rettner). According to the Mayo Clinic, this hormone plays a role in sex drive, sperm production, fat distribution, red cell production, and maintenance of muscle strength and

MacLean et al. (2015) addresses the efficacy for the GnRH antagonist TAK-385, based on a three-part, placebo-controlled study. The study examined (n=176) healthy UK males, with the age range of 19 to 75 years old. The first part included the dose of TAK-385 20-mg tablets or a placebo. The 14-day part two included the daily dose of TAK-385 20-mg tablets or a placebo. The 28-day part three included the daily dose of TAK-385 20- or 80-mg or a placebo. In part 1, luteinizing hormone (LH) levels decreased, as well as serum testosterone levels. In part 2, with doses of at least 40 mg/d, LH and follicle-stimulating hormone (FSH) levels decreased and after multiple doses the mean testosterone levels dropped below the threshold for medical castration. In part 3, serum testosterone levels dropped most rapidly and medical castration was achieved. Doses greater than 80 mg/d of TAK-385 reduced the serum testosterone levels below castration levels. Conclusively, GnRH is a valid option for testosterone suppression and ultimately serves as an effective prostate cancer hormone therapy treatment.

Although low testosterone is a very common issue, something else may be going on, and other problems with these symptoms need to be eliminated. If the problem is low testosterone, a booster may be of help," Wilson continues.

Luteinizing hormone releasing hormone (LHRH) agonists therapy may be used to enhance a negative feedback loop between the anterior pituitary and testicles, thus inhibiting the production of TST. LHRH agonists replicate the effects of endogenous luteinizing hormone which cause an acute rise in TST production — followed by a significant decrease in long term TST levels. LHRH antagonists may be used to disrupt the hypothalamic pituitary axis and inhibit the production of male sex androgens. The therapeutical index of LHRH antagonists may be greater than that of LHRH agonists because they do not cause the acute flare in TST as

Testosterone is released from the leydig cells and circulates the body. Like estrogen, testosterone can enter the target cell, bypassing the cell membrane and is transported to the nucleus by a carrier protein. Testosterone is also a transcription factor in which testosterone binds to genes and influences the function. Depending on the type of cell, testosterone can be converted into another form before reaching the nucleus. Only about seven percent of circulating testosterone is converted to dihydrotestosterone (DHT) and less than one percent is converted to estrogen. Testosterone first takes effect in the womb, allowing male reproductive organs to differentiate from female organs. The presence or absence of testosterone determines whether a baby will be male or female. At the onset of maturity, testosterone also signals other cells in the testes to begin production of sperm. Secondary sex characteristics include hair distribution on the face and body, the deepening of the voice as testosterone causes a growth in the larynx, induced male pattern fat distribution, bone growth, increase in sex drive and behavior. The hypothalamus regulates the amount of testosterone circulating the body by releasing follicle stimulating hormone and luteinizing hormone (Nieschlag, Behre, and Nieschlag, 2012). Testosterone utilizes a negative feedback loop by acting upon the hypothalamus to inhibit GnRH release and on the pituitary

There’s 800 pounds bending that bar. Count the plates. And Ronnie’s bangin’ it out for REPS!

Napoleon could be argued as a great leader because he help France have many freedoms that other countries did not have at the time. For example Napoleon created states that granted constitutions, introduced laws and codes, and abolished feudalism. Furthermore he supported education, science, literature, and arts. One of the laws and codes napoleon created was the toleration for religion.

This product focuses not only on offering strength, lean muscle, energy and fast recovery, but also on boosting the level of testosterone.How does Crazy Mass Testosterone MAX Elite Series work?

Ladies world over fear "fifty". While men get devious at forty, ladies get confounded at fifty! This age is the age when a lady encounters menopause. For some ladies, menopause is a frightful period that is set apart by hot flushes, lavish sweating, sleep deprivation, vaginal dryness and emotional episodes. Amid menopause, a lady's body experiences extraordinary physical and mental changes also. Decreasing levels of estrogen and progesterone cause a considerable measure of issues for ladies. These hormones are in charge of the menstrual cycle as well as shield them from genuine maladies of the heart and the bone like osteoporosis. The current science has an impeccable answer for these issues called the "Hormone substitution treatment".

Testosterone and Estrogen are the male and female hormones that control how either gender develops. “Between weeks 8 and 14 of fetal development, before the fetus’s sex is determined, tiny fetal ovaries (which may turn into testes depending on the chromosome factor) and adrenal glands release the embryo’s own supply of androgens. These chemicals then cause chain reactions in the body, spurring the growth of the genitals (determined by chromosomes), causing major growth in brain regions and impactful change in

Alchemy was a turning point in the field of science during the Middle Ages, and paved the way for many of the greatest scientists in history, including Albert Einstein. Contrary to popular belief, alchemy is not just about “science,” but also about humans spiritually and mentally. Alchemy may have been lost over the course of many centuries, but it is still very much alive in our society today, through our relationships with other people and within ourselves. Robert of Chester’s translations of Arabic alchemical books allowed for the spread of alchemy throughout Europe beginning in 1200.

Osteoporosis is often found in elderly women with low levels of estrogen and calcium. The number of available research based on osteoporosis in women outnumber that of their male counterparts. Little researches have been conducted on the relationship between testosterone levels and osteoporosis in men. In this paper, we will review 5 difference sources to determine if testosterone levels affect the chances of men developing osteoporosis. The following three questions will be answered in this paper: Are women more prone to osteoporosis compare to men due to their low level of testosterone? Is low testosterone the main cause of osteoporosis in men? Is testosterone therapy effective in reducing or cure osteoporosis in men?

The male reproductive system is effect by the cause of oligospermia and azoospermia, decreased the testicular size, abnormal appearance of testicular biopsy material, and reductions in testosterone and gonadotropic hormones. The change in the body seen in the pituitary-gonadal which leads to the suppression of gonadotrophin production. The variations in these hormones can alter thyroid function and negative impact on glucose tolerance. The Abuse of steroids affects the male reproductive be reversible with cessation of steroid that can cause, although breast tissue changes and hair loss. It can lead to surgery needs of an

People have natural testosterone that their bodies create. For males, they produce testosterone in the leydig cells of the testes. For females, on the other hand, they produce it in the ovaries. However, males tend to make about ten times more testosterone than females. As males grow older, the amount of testosterone they produce increasingly deteriorates. Anabolic steroids like to take over the natural testosterone in the body which messes with the bodies normal functions and ruins the bodies internal harmony (Allen, 2017). This can cause a lot of health problems for people this happens