The leading cause of death for people in the United States is heart disease. Heart failure is just one of the many conditions that underlie heart diseases. Being one of the leading causes of death; having the knowledge on how this disease works can help researchers find a cure or new treatments to prevent and/or treat this pathogenesis. Chronic inflammation is a condition that can lead to heart failure. When inflammation is chronic it means that the inflammation is long-term and therefore this condition can lead to other complications, but what causes chronic inflammation? Inflammation is a response to a foreign pathogen in the body, but what if there is no foreign pathogen? An autoimmune disease occurs when the immune system starts to attack the healthy …show more content…
One of the outcomes of the complement pathway is inflammation. So, if there is an imbalance of the components of alternative pathway when activating the complement system this will lead to chronic inflammation, therefore, leading to heart failure. This hypothesis/theory can lead to further investigations to see if there is a way to stop or decrease the excess of components that lead to inflammation. The results from the author’s paper were interesting because they discovered that “the alternative pathway in heart failure is activated when the levels of enhancers and inhibitors of the alternative pathway are altered, which would normally occur with patients with heart failure“ (Shahini, et al, 2017). This dysregulation could give rise to other complication as mentioned before like inflammation. So, this correlation of chronic inflammation with the altered balance of enhancers and inhibitors of the activation of the alternative pathway is what makes heart failure a progressive disease that causes loss of cardiac function ultimately leading to
While a natural response to pain and injury, inflammation is also related to some debilitating conditions and diseases. The tame end of symptoms include headaches, weight gain, and joint pain. But heart disease, Crohn’s disease, and even some types of cancer are also related to chronic inflammation. And chronic inflammation wasn't something treatable fifty years ago, before the advent of Systemic Enzyme Therapy. Now there is Heal N Soothe.
Heart disease, sometimes called cardiovascular disease, is the narrowing or blockage of blood vessels around the heart. It is affected by many factors. Some of these factors include age, gender, obesity, high cholesterol, lack of physical activity, diabetes, hypertension, smoking, as well as genetic heart defects that one might be born with. The question now becomes how do these risk factors affect or impact heart disease. Are the factors necessary, sufficient, or component causes? Someone with a healthy heart will generally not have problems associated with heart disease, except perhaps though drug or alcohol use. Someone with heart disease, however, has a heart that has been damaged through one of the
Over the past few years cardiovascular diseases have become the number one global cause of death. These diseases were first discovered 3,500 years ago with the Egyptians, and ever since then the causes have been pretty much the same. Although there are things that can be done to either increase or decrease the chances of getting heart disease. “Heart diseases describe a range of conditions that affect the heart” (Sheen 1). It can range from a myocardial infarction- a heart attack-, to a cerebral vascular disease, which is a disease of the blood vessels. Either way these diseases can impact the life of people in many negative aspects. Cardiovascular diseases have become the number one cause in global death due to the bad habits, diets, stress, and natural and chemical causes that the global population has.
Whether it is arteriosclerosis, congestive heart failure, broken heart syndrome, coronary microvasculature disease, or coronary heart disease, the National Institute of Health reports that "heart disease is the number one killer in the U.S.[and] also a major cause of disability." The good news is that there are things that can be done to lessen the chance of having a heart disease-related incident.
Heart Failure is a progressive heart disease when the muscle of the heart is weakened so that it cannot pump blood as it should; the blood backs up into the blood vessels around the lungs and the other parts of the body (NHS Choice, 2015). In heart failure, the heart is not able to maintain a normal range cardiac output to meet the metabolic needs of the body (Kemp and Conte, 2012). Heart failure is a major worldwide public health problem, it is the end stage of heart disease and it could lead to high mortality. At present, heart failure is usually associated with old age, given the dramatic increase in the population of older people (ACCF/AHA, 2013). In the USA, there are about 5.7 million adults who have heart failure, about half of the people die within 5 years of diagnosis, and it costs the nation an estimated $30.7 billion each year (ACCF/AHA, 2013).
Also, the reasons we all know, obesity. The extra fat in your body can be a major problem. Usually patients with obesity, hypertension have more chances of getting a heart failure.
There are numerous health disparities and issues worldwide affecting all different people in the United States. Some of these issues tend to affect our population. Many people lack the knowledge of how heart disease is developed. Heart Disease is the leading cause of deaths. Over 600,000 Americans die from heart disease each year. Anyone can develop heart disease, regardless of a person’s age, gender, and ethnical background. In some cases, people are born with heart disease.
According to Centers for Disease Control and Prevention, Cardiovascular disease (CVD) is the leading cause of death in the world, responsible for 30% of all deaths globally (WHO) 1 -3 deaths in the U .S. (CDC).
Cardiovascular disease has reportedly been the number one disease killer for men and women in the United States of America. Every one out of four deaths is caused by heart disease in the United States alone (Centers for Diseases Control and Prevention). Heart disease refers to the different types of conditions and symptoms that can affect the one’s heart and its functions to the body (Mayo Clinic). Cardiovascular/Heart disease has many causes and conditions, prevention methods and symptoms, and treatment options.
According to the WHO, cardiovascular diseases have been the leading cause of death globally claiming 17 million lives a year, more deaths than all cancer combined (Chiu and Radisic, 2013). Cardiovascular disease is responsible for a preponderance of health problems and its impact is expected to grow further as the population ages. In the UK, NHS spends about £7.74 billion as the expenditure to deal with cardiovascular diseases (Barton et al., 2011). Cardiovascular disease in the form of myocardial infarction has become the principle cause of death in developed countries, accounting for nearly 40% of all deaths (http://www.bhf.org.uk/). Congenital heart defects, which occur in nearly 14 of every 1000 new-born children, is another tragic fact that baffles medical industry (http://www.heart.org/). About 61 million Americans (almost one-fourth of the population) live with cardiovascular diseases, such as coronary heart disease, congenital cardiovascular defects, and congestive heart failure.
Cardiopulmonary Disease is one of the leading causes of death for both men and women of all ages in the US. Cardiopulmonary Disease is a disease that many people have, and half of those people that have the disease are unaware of it. Cardiopulmonary Disease involves both the heart and lungs (McMahon, 2014). Cardiopulmonary Disease can involve inflammation which shuts down the airways and narrows the coronary arteries, along with infections and ongoing diseases. One example of Cardiopulmonary Disease is chronic obstructive pulmonary disease (COPD), which makes it hard to breathe and results in subsequent heart problems for the patient over time. The heart is strained by the extra work it has to engage in to get blood through the lungs for oxygenation, and may eventually give out (McMahon, 2014).
One significant disease is the coronary artery disease. The coronary artery disease, also known as CDA, is the most common of the heart diseases. CDA is the leading cause of death in the U.S. in both men and women. CDA is known to cause the heart muscle to become narrow and hardened. These symptoms could lead to chest pain (angina) or a heart attack. Over time, this could lead up to the heart weakening and can cause heart failure arrhythmias.
According to the American Heart Association (2015), heart failure is defined as “a chronic, progressive condition in which the heart muscle is unable to pump enough blood through to meet the body 's needs for blood and oxygen. Basically, the heart can 't keep up with its workload”. Congestive heart failure is a progressive illness that effects millions of Americans every year. Many other illnesses can lead to the development of congestive heart failure. Examples of these diseases include: coronary artery disease, past heart attack, high blood pressure, abnormal heart valve, heart muscle disease such as hypertrophic cardiomyopathy, dilated cardiomyopathy or inflammation such as myocarditis, congenital heart disease, severe lung disease, diabetes, obesity and asthma. (American Heart Association, 2015 (Centers for
Coronary heart disease is caused by the narrowing of the coronary arteries which is because of the deposition of fats and cholesterol on the inside lining of the arteries. These deposits which also cause hardening of the walls of the arteries also block the flow of oxygen to the heart. This deprives the heart of the needed oxygen that is required for its proper functioning.
lives. A simple definition of a heart attack is a sudden failure of the heart