The most common way to take medicine is orally. Once the medicine is ingested through the mouth, it goes through the digestive process to eventually be distributed into the organs and tissues. The medication can travel through the body more than once if the medication was not fully dissolved in the first travel through. Within the stomach, acidic juices help to break down nutrients from food or other substances and eliminate bacteria that were on or in the ingested substance. (Howell, 2016) The digestive process happens when food or anything ingested passes through the gastrointestinal tract. The typical route of the consumed food is the mouth, to the esophagus, to the stomach, next to the small intestine then lastly to the large …show more content…
And if the pill has a very strong outer coating, it may dissolve in the small intestines. The gastric juices help to dissolve the medicine because of its high acidic levels. (Howell, 2016) Stomach acid, also known as gastric juices, is mostly made of hydrochloric acid and also consists of water, electrolytes, enzymes, mucus, and intrinsic factor. Gastric acid in the body helps to protect the gastrointestinal tract from harmful bacteria that has been consumed. Since stomach acid is very acidic, it is able to do all of its needs such as, break down nutrients and kill harmful bacteria. (Lehman, 2016) (McDade & Cloos, 2009) The concentration of hydrochloric acid in the stomach acid varies between 5,000 and 10,000 parts per million. Levels of pH vary between1 and 12. If a substance has a pH of 12 it is the very basic, while a substance with a pH of 1 is very acidic. Stomach acid has a pH that varies between 1 and 3, making it very acidic. In comparison to water, normal gastric juices’ levels are 100,000-1,000,000 times more acidic. (McDade & Cloos, 2009) (National Center for Family Learnings, 2014) Foods and liquids have different effects on medication in the body. For example, Norman Tomaka research shows that hot liquids can affect the outer coating, releasing the medicine quicker. Dairy products are shown to limit the absorption from the stomach to the blood. The pH of some liquids may also affect the distribution of some
The majority of medicines are formulated for oral administration. This means they are taken via the mouth, in the form of a tablet, capsule, liquid or suspension. These medicines come in a variety of
The aspirin starts begins to dissolve by the enzymes and are soaked in while traveling down to the stomach. They then are distributed to the areas that need the pain relief.
into ammonia, and thus neutralizing the surrounding acidic environment. Also, H. pylori contains "hydrogenase" enzyme, which can oxidize molecules hydrogen being produced by other gastric bacteria, in order to produce energy. Some other enzymes that can be utilized by H. pylori are "oxidase" and "catalase", which are also used to test for the presence of this organism. It can also form "biofilm" on the gastric mucosa epithelium, which results in its ability to resist against many antimicrobials. From spiral form, it is able to convert into "coccoid form" - one of its advantage which helps in its survival and epidemic potential [5].
The National Prescribing Centre recognize some fundamental differences in the absorption, distribution and excretion of medicines between adults and children. The differences are published in the National Prescribing Centre’s bulletin, produced by
This is medication that is taken via the mouth. This can be in the form of tablets and capsules. If an individual finds it difficult to swallow tablets oral medication is also available in liquids, suspensions and syrups. Sublingual medications are for example when tablets are placed under the tongue to dissolve quickly.
The stomach is an organ that is part of the digestive system. The stomach is located in the upper left part of the abdominal cavity, below the diaphragm and next to the liver (Stomach, 2013). The inner walls of the stomach contain small pores called gastric pits. The gastric pits contain cells that secrete chemicals that aid in the digestion of food (Nguyen, 2015). In this essay, I will discuss the different cell types of the stomach, how they work together to provide the overall function of the stomach, why each organ requires different cell types, why the stomach can’t be comprised of just one cell type, and the advantage of having different types of cells.
Oral - medicines can be given orally in the form of capsules, tablets, liquids or powders.
Absorption – “How the drugs enter the circulation process through the body, and how they resist general breakdown by the stomach, liver, and the intestines”. Some of the factors that affect the absorption of drugs in the body is as follows, “acidity of the stomach, Physiochemical properties, Presence of food in the stomach or intestine, and Routes of administration”,
Pharmaceuticals come in all different forms. it makes them easier for the user to consume in the way that suits them best. These different medicines come in many forms such as pills. A small pill is easy to swallow and then it takes care of the rest; this is the most common and regularly way. Chewable pills or gummies are for the ones who cannot swallow a pill.
Pharmacokinetics "is the way a drug is absorbed, distribution, metabolism, and excretion (pg. 749 Treas)
The hypothesis was formed under the thought that the fastest dissolving pill would be the most effective because the sooner the ingredients and materials were realized, the sooner they would be able to attack and neutralize the pain, therefore getting the job done quicker or more efficiently. The hypothesis was not supported because, overall, the first two pills to dissolve were both children’s pain killers and were “junior strength”. Therefore, these medicines could not have been the most effective because the strength is significantly weakened to accommodate to young kids, and would not be as effective as normal strength medicines. In order to accurately determine the time taken for the pills to dissolve inside the body, it is very important to create a solution similar to stomach acid. Stomach acid was simulated by heating vinegar, which has the same ph level of stomach acid and shares other similarities in makeup and properties. The vinegar was heated to 36.7 degrees Celsius and constantly stirred to represent the temperature and motion of stomach acid. Eight different pills were timed to see how fast they dissolved. Each type of pill was tested three times in order to find an average for each medicine. The pills tested were Advil, Children’s Advil Grape Flavored, Ibuprofen, Children's Ibuprofen Grape Flavored, Tylenol, Tylenol Liquid Gels, Aleve, and Aleve Liquid Gels. The children's strength pills were the first two medicines to dissolve. Aleve was the slowest to dissolve and took almost two hours to dissolve. The liquid gel capsules were the second and third slowest pills to dissolve. In order, from fastest to slowest to dissolve, the medicines were Children's Ibuprofen Grape Flavored, Children’s Advil
Pharmacokinetics consists of three components, absorption, distribution, and clearance. Absorption, especially from the oral route is the least influenced by the aging process and slows down, but remains complete (Adams et al., 2011). As the number of drugs ingested increases, the risk that absorption is interrupted increases (Adams et al., 2011). Distribution is significantly impacted with age. Older people have more body fat and less water than younger people. As a result, a drug that is fat soluble will remain in older bodies
Oral. Tablets, liquids, and capsules are swallowed. The antibiotic is released in the small intestine to be absorbed into the bloodstream. Troches, or lozenges, are allowed to dissolve in the mouth, where the antibiotic is absorbed through the mucous membrane. Parenteral.
The stomach is an expandable muscular sac that is capable of holding 2-4 liters of food and liquids and breaks them down with the use of pepsinogen, an inactive form pepsin, a protein-digesting enzyme. If the stomach was damaged or dysfunctional, then it would be harder to gradually release food into the small intestine at a rate suitable for proper digestion and absorption and to digest the food because it is not as small or digested because the stomach also assists in the mechanical and chemical breakdown of the food as well as the killing of harmful bacteria due to the high acidic environment due to the hydrochloric acid. (Audesirk, T., & Audesirk, G. (1999). Retrieved November 21, 2015 from Chapter 29: Nutrition and Digestion. In Biology:
Digestion is the chemical breakdown of food into smaller components that are more easily absorbed. Digestion is a form of catabolism: a breakdown of large food molecules to smaller ones. When food enters into stomach, gastric juice starts protein digestion. Gastric juice mainly contains hydrochloric acid and pepsin. The pH value of hydrochloric in the stomach is 2, as the activity of pepsin is optimal, while it will lose its activity at pH 6.5 and above. However, pepsin will regain its activity at pH of 8. In the range of pH1 to pH6.5, pepsin will be most active at pH2, and starts to decrease its