methamphetamine), also known as ecstasy or “Molly,” is a psychoactive drug that is similar to both the stimulant drug amphetamine and the hallucinogen mescaline. Those taking the drug typically experience feelings of increased energy, euphoria, emotional warmth and empathy. However, there can also be negative side effects to its use, including confusion, depression, insomnia, and anxiety. Additionally, heavy users also experience confusion, memory loss, and problems with attention. It is unknown whether or not the drug is addictive, but some experiments have shown that some users report symptoms of dependence, tolerance, and withdrawal. (Volkow, 2013)
MDMA works in the brain to increase the activity of serotonin, dopamine, and norepinephrine
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All patients were injected with a radioactive marker that binds to serotonin re-uptake sites on the axons of 5-HT neurons. It was shown that the marker binds to 22% fewer sites in MDMA users. Researchers believe that this decreased binding indicates that the serotonin transporters have been damaged. It is believed that this damage may have negative consequences long term, including anxiety, depression, and memory disturbances. (McCann, …show more content…
Using a purified form of MDMA, researchers reduced blood flow to areas of the brain that have been linked to emotion and memories. This decrease reduces neurotransmitter communication between the temporal lobe and the prefrontal cortex, which are involved in emotional control. For this reason, MDMA has been considered in the treatment of patients with uncontrollable post-traumatic stress disorder (PTSD). In patients with PTSD, taking a single dose of MDMA was shown to decrease activity in areas of the brain that store negative or bad memories, and increasing or exciting the areas of the brain that store good memories. (Carhart-Harris,
Methamphetamines (Meth) cause a wide array of problems with its users, a lot of which are permanent. Meth’s affects range from neurological issues, alertness, paranoia, and aggression. It also leads to psychological and physical disorders. Because Meth is a stimulant, it can cause the user to be up for days and even weeks at a time causing stress to the body and can result in over exerting oneself and inevitably something will give. Personal problems from users will be talked about, as well as scientific studies on the Meth epidemic.
The axon terminals after the neurotransmitters are released are supposed to reabsorb the extra neurotransmitters. The lack of serotonine in the neurons cause a lack of serotonine transporters, the spots on the neurons responsible for reabsorbing serotonine. Ecstasy blocks the re-uptake of serotonine by the synaptic terminal. The serotonine becomes toxic and begins to kill off brain cells (“After the Rave: the Ecstasy Hangover”, (www.faculity.washington.edu/chudler/mdma.html).
MDMA has not always been viewed in a negative light. Its health benefits can be traced back to the mid-twentieth century. With the homecoming of World War II soldiers, MDMA use was found to be more prevalent in society. The correlation between the homecoming of the soldiers and the spike in MDMA usage led scientists to research the situation further. The scientists found that MDMA held psycho-related benefits which was most prominent in those who suffered from Post-Traumatic Stress Disorder (PTSD). Those suffering with PTSD had a hard time coping with their emotions. They felt more detached from others and had sporadic behaviors that could lead to verbal or physical abuse. In the wake of World War II, the discovery that a drug could lessen
Meaning out of all the drugs that are out there, Molly has a high potential for abuse. Molly is also classified as a mild hallucinogen and a psychedelic. Meaning that when someone is high on molly, they would hallucinate and start to see or hear things that are not really there. When Molly is taken, it acts as a central nervous system stimulant. The MDA absorbed through the body destroys serotonin-producing neurons in your body. These neurons role in your body is to regulate aggression, mood, sexual activity, sleep, and sensitivity to pain. This is why when people are high off of Molly, they have trippy dreams and feel unstoppable. Molly can be snorted, injected, but is mostly found in pill form. When in the form of a pill, they come in many different colors with pictures on the top to look
MDMA or Ecstasy is a synthetic, psychoactive drug similar to methamphetamine a stimulant and mescaline a hallucinogen. Ecstasy has several slang names including Molly, E, Adam, Hug Drug, Love Drug, XTC, and Essence.
Some short-term effects of taking this drug include an increase in wakefulness and physical activity, a decreased appetite, rapid heart rate, irregular heartbeat, increased blood pressure, hyperthermia, convulsions, and potential death. The pleasurable effects of meth are result from the release of very high levels of the neurotransmitter dopamine, which is involved in motivation, the experience of pleasure, and motor function. The elevated release of dopamine also contributes to the drug’s deleterious effects on nerve terminals in the brain. Some long term effects include anxiety, confusion, insomnia, paranoia, visual and auditory hallucinations, delusions, and mood disturbances and violent behavior. Some side effects include hyperactivity, dilated pupils, flushed skin, excessive sweating, increased movement, dry mouth and teeth grinding, headache, irregular heartbeat, rapid breathing, high blood pressure, low blood pressure, high body temperature, diarrhea, constipation, blurred vision, dizziness, twitching, numbness, tremors, dry skin, acne, and pale appearance. Other effects of abusing this drug include memory loss, aggression, psychotic behavior, damage to the cardiovascular system, malnutrition, and severe dental problems. Beyond these effects along the body and brain, methamphetamine abuse also threatens whole communities by causing new waves of crime, unemployment, child neglect or abuse, and other
The subjects were given different doses of MDMA sporadically. The Kirkpatrick's group expectancy that the inhaled oxytocin and molly did increase oxytocin levels in the blood. This indeed signifies that the increase in oxytocin levels do account for the popularity of this party drug.
When MDMA is taken, it enters through passive diffusion (Granquist L.,2014), or the reuptake transporters into the serotonin axon terminal of the neurons in the brain. The MDMA then causes much of the stored serotonin in the axon terminal vesicle to be released. As the electrical signal travels down the axon it also causes release of the other two neurotransmitters, dopamine and norepinephrine. (Volkow, 2014).
The illegal drug i'm researching is ecstasy. X, E, or XTC, Adam, Beans, Candy, Dancing Shoes, Disco Biscuits, Doves, E-bomb, Egg Rolls, Happy Pill, Hug Drug, Love Drug, Malcolm (or Malcolm X), Molly, Scooby Snacks, Smartees, Sweets, Skittles, Thizz, Vitamin E or Vitamin X, Vowels are all examples of street names for ecstasy. Ecstasy is the common name given to the drug Methylenedioxymethamphetamine (MDMA). It was accidently created by Mannish and Jacobsohn, two German Scientists working for Merk in 1912. It was believed to be used as a weight loss drug however it wasn't heavily marketed. The purpose of ecstasy is to make you feel happy and very excited. Also all problems you would have they would disappear like they were never there before.
In Carolyn Gregor’s magazine article “8 Fascinating Things We Learned About The Mind in 2015”, she wrote about different people’s chemical abuse , personal lifestyles and environmental choices can affect how the mind reacts to inner workings. Studies found from Script Research Institute may have discovered a new drug which could influence the addiction associated memories in people who are user of meth and other mind altering drugs. This drug will be absorbed into the brain and eventually dissolve past memories which are triggered drug use.
A General Overview of Ecstasy 3,4-Methylenedioxymethamphetamine, better known by its street name, ecstasy or molly, is a type of illegal, synthetic drug that is typically found in the form of pills, tablets, or a capsule. It is slowly becoming one of the most popular recreational drugs worldwide. Among the ages ranging from 18 to 25, about 25 percent of them have admitted they have used the drug at least once in their lifetime (Lesley, W. R. et al., 2007). These drugs are typically used at nightclubs and raves, but recently, due to its popularity, it can be more commonly found in homes for private usage as well. Ecstasy was extremely common during the 1980s and 1990s due to the rave counterculture that was introduced (Lesley, W. R. et al.,
Drugs have been around for a very long time. They are used for a variety of reasons. Some of these reasons include relaxation, socialization, curiosity, stress relief, or a form of escapism. However, most people don’t know the threats and danger that it can cause to the body. In this paper, we are going to examine the changes that happen inside the brain due to the effects of different drugs. We will look closely at how drugs such as hallucinogens, ecstasy, cocaine, heroin, and cannabis affect an individual psychologically. I will explain the origin of the drugs, how a person feels while on the drug, how the drugs
In a study funded by the Multidisciplinary Association for Psychedelic Studies (MAPS) and published in the Journal of Psychopharmacology, trials showed that “(a) decrease in Clinician-Administered PTSD Scale scores from baseline was significantly greater for the group that received MDMA than for the placebo group at all three time points after baseline” (Mithoefer, Wagner, Mithoefer, Jerome, & Doblin, 2010, p. 1). 83% of entrants saw a recession of
Methylenedioxymethamphetamin (MDMA), also known as Ecstasy, is one of the most powerful hallucinogenic drugs in Schedule I. Like most drugs, MDMA has high potential for substance abuse. When made available to the general public, MDMA was seen in a bad light. The potential adverse health effects include but are not limited to: nausea, chills, sweating, involuntary jaw clenching, teeth grinding, muscle cramping, blurred vision, as well as dehydration and hyperthermia. These negative aftereffects occur because MDMA reduces serotonin levels in axon terminals by releasing large amounts of that particular neurotransmitter. By increasing the activity of neurotransmitters, MDMA becomes a quite powrful stimulant and can affect the user’s mood, appetite, and sleep cycle in various ways (“What Does MDMA Do to the Brain?” 2006). The question is, can this drug’s effect on one’s mood and neurotransmitter levels be used in a positive way with the proper setting?
An individual’s behavior and emotion becomes chemically altered often resulting in dependency, aggression, onset of diseases and poor judgement. This poses a dangerous threat to the neurotransmitters since they have multiple jobs in different parts of the brain. Drugs of abuse are able to exert influence over the brain reward pathway either by directly influencing the action of dopamine within the system, or by altering the activity of other neurotransmitters that exert a modulatory influence over this pathway. These drugs are often powerful and have been known to trigger schizophrenic behavior and can also cause a person to cease breathing, for example hallucinogens such as LSD, mescaline, and psilocybin are able to artificially stimulate the serotonin receptor (Sapolsky, 2005).