Effect of AA content on the swelling ratio of hydrogel Fig. 3b shows the effect of AA on the Q value of hydrogel. With increasing concentration of AA, the Q values of hydrogels increased and then decreased. When AA amount was more than 7 g, the Q values of hydrogels decreased because when the concentration of AA was high, the collision probability between monomers would increase, thus increasing the graft length of sulfonated cellulose, favoring the formation of a polymeric network at higher Q values
The title of this article is “Multicenter Cohort Study to Assess the Impact of a Silver-Alloy and Hydrogel-Coated Urinary Catheter on Symptomatic Catheter-Associated Urinary Tract Infection” (Lederer, Jarvis, Thomas, & Ritter, 2014). The title it self-give us lot of information about this study, just by looking at the article we can identify the independent variable (silver-alloy hydrogel catheter), dependent variable (symptomatic catheter-associated urinary tract infections), and the purpose of
synthesized in 3 step reactions, and the hydrogels may be biodegradable in vitro and have minimal cytotoxicity in a human retinal pigment epithelial cell line [100]. The histomorphology and electrophysiology was studied in rabbits and the neuroretina was preserved after 2 months of intravitreal injection. In another instance, the administered intravitreal release profile of bevacizumab from poly(ethylene glycol)-poly-(serinol hexamethylene urethane) (ESHU) hydrogel was also studied for 9 weeks, and averaged
Gel hydrogels can be considered as promising materials to be used as scaffold in tissue engineering since they present a load-bearing capacity and suitable mechanical properties.6 Almost all the measurements on the mechanical properties of hydrogel materials have used true stress-true strain or engineering stress-engineering strain definitions on the grounds of hydrogel incompressibility.26 However, there is no agreement as to which stress-strain definition should be adopted to determine the mechanical
degeneration (AMD), cataracts, cancers, corneal wear, diabetic retinopathy, glaucoma, inflammation, keratoconus, retinal detachment, and retinitis pigmentosa. The following section is a summary and a discussion of the progress on the research on injectable hydrogels in the treatment of the aforementioned diseases and disorders. 3.1 Corneal abrasion and keratoconus 3.1.1 Cause of disease and treatment The epithelial surface of the cornea is vulnerable to mechanical wear and may cause temporary pain and reduced
Stability of therapeutic proteins in hydrogel drug delivery systems Abstract: Arthritis constitutes represents one of the major serious conditions that negatively impact affect the patients? quality of life (QoL) of affected patients here in Egypt. Arthritis is associated with comorbid conditions, physical and mental debilitation, increased level of depression and negative influence on life expectancy. Thus, great care is directed to effectively treat this medical condition. Unfortunately, conventional
There have been a significant development in the field of hydrogels made from 2-hydroxyethyl methacrylate (HEMA). HEMA is the monomer of the polymer poly2-hydroxyethylmethacrylate.This polymer has the remarkable property to get swelled due to the molecule’s hydrophilic pendant group when subjected to water. It is capable of absorbing water from 10 to 600% relative to the dry weight. Because of its unique property, it was one of the first material to be used in contact lenses. Xanthan gum is a polysaccharide
lambda-carrageenan through the use of Heckel plots out of die tablet densities. The results proved linear. Both carrageenan types yielded near zero-order profiles in drug release tablet formulations. The tablet compression pressures had little to no effect on the profiles from 70 to 175 MPa. It was found out that while drug loading increased from 5% to 20%, the exponent of diffusion decreased from 1.056 to 0.678. From zero-order release, the breakup of tablets during the dissolution and departure were
factor (KGF), fibroblast growth factors (Lee et. al.,2010), epidermal growth factor (EGF), Platelet derived growth factors (PDGF) (Grazul-Bilska et. al., 2003) etc. These growth factors are generally delivered topically using different dressings like Hydrogel dressing, Collagen film, Hyaluronate and Alginate dressings to the wound site. Bioactive dressing should fulfill several criteria for its optimal function: 1) biocompatibility in the absence of cytotoxicity, 2) easily applied to the wound, able to
3D Hydrogel Scaffold for Characterization of Ovarian Cancer Tumor Cell Growth Courtney Dreyer | A09795311 Jenny Pan | A97020570 Julia Wong | A09901322 Abstract Ovarian cancer is of significant concern to women because it is both hard to diagnose and aggressive. As of current, there is a lack of viable in vitro models that accurately model ovarian cancer tumor metastasis and growth. The purpose of this research is to develop a viable 3D hydrogel that enables the ovarian cancer cell environment to