Thalidomide Paper Thalidomide is a drug that was invented in Germany in the 1950’s. It was originally intended to treat respiratory infections but during testing, it was noted that the drug worked to relieve morning sickness for pregnant women. This new reason allowed the drug to be prescribed to many new patients all over the world. Eventually Thalidomide was discovered to be causing birth defects in all of the pregnant women that were taking it. It caused the fetus to not develop correctly by causing limbs of the body or ears to develop improperly or not develop at all. It also cause spinal cord and digestive system defects as well as problems to the heart and kidneys. Thalidomide stopped being prescribed but not before many children and families were affected worldwide who had taken the drug. It took a couple of years before other countries caught up to realize that thalidomide was causing the birth defects and removed from being an over the counter drug in many countries. It wasn’t until 1961 that it was completely removed after it was confirmed that it was causing birth defects. More than 10000 babies were born with defects and approximately killed 2000 before birth, but fewer than 100 were born here in the U.S.
Short term effects included possible still born babies, and children with many health problems and complications that severely impacted their quality of life. How much damage the Thalidomide did to the fetus depended on how early on the mother took the drug.
As you may know, I am what you may consider a creep or freak. I'm here to explain the incident that occurred during that Skype call in early August.
not give because : fetal damge and congental malformation , life-thretening with drawl symptoms in a newporn also the drug can pass into breast milk
The author believes nature is a way to be truly alone and sees it as the embodiment of perfection and beauty. Ralph Waldo Emerson uses figurative language (symbolism), comparison, and contrast to convey his message. In the passage, the author uses symbolism to portray to the reader how he feels about nature. He states “His intercourse (communication) with heaven and earth becomes part of his daily food.” This is symbolism because he is using food as a symbol for how necessary it is for Someone to communicate with nature.
Physical effects: tumors/lesions/sudden deaths/weight of various organs/malformations/etc. in animals and offspring. These studies’ primary goal is to rule out major effects: birth defects, cancer, etc.
A little white pill, sold as an over-the-counter drug, lined the shelves of pharmacies across the globe. Originating from the German drug company, Chemie Grütinethal, this pill was advertised to a highly receptive international market and was a success in 1959. Several years later, physicians began to form a link between phocomelia, a birth deformity, and pregnant woman who ingested the German-created drug. That little white pill is known as Thalidomide. Staying in the market for almost six years, Thalidomide changed the lives of mothers and their newborns for the worse making it one of the largest pharmaceutical failures in the course of mankind. Although the horrific effects of distributing Thalidomide in the late 1950s is historically
term effects will range from 1 year to the rest of the person 's life. All the short term effects as “
efforts to restrict its use. Some believe that advances in medical technology have contributed to its overuse.Two of the primary issues that arise with the treatment include whether or not it is “necessary” in certain cases and whose safety needs to be taken as a priority, especially in a case of twins. With a breakthrough this big that has the power to save children from innumerable
chemicals. Many women, who took diethylstilbestrol (DES) to prevent miscarriages, increased the risk for breat cancer in their children.
It can also cause defects in the heart and spine, intellectual disability, delays in physical development, behavioral problems, and being impaired hearing and visually.
Nowadays, the drug is only used for advanced cancers and severe complications of leprosy. Also, due to the German measles (Rubella) epidemic in the United States in 1962, thousands of children were born with birth defects. Sometimes, the pregnant women were also affected by these high risk pregnancies. However, these women could not seek abortions due to the strict bans. (Supreme Court Drama, wikipedia.org, time.com)
Waiting eagerly for a decision from the Food and Drug Administration (FDA), pro-choice and pro-life activists rallied to voice their opinions on the drug mifepristone, also known as RU-486. However, the battle has just begun because RU-486, otherwise known as the abortion pill, was just approved for use in the United States on September 28, 2000. This controversial drug, first used in France, has been sparking debates in the U.S. ever since it was discovered in 1980. Now that it has been approved, many argue that this drug will make abortion more prevalent; however, others believe the approval of RU-486 is a positive decision and can greatly benefit women in the future.
There were two important developments in the 1970s which further shaped the industry in the form that we see today. Firstly, the Thalidomide tragedy (where an antiemetic given for morning sickness caused birth defects) led to much tighter regulatory controls on clinical trials, greatly increasing development costs. Secondly, enactment of legislation to set a fixed period on patent protection (typically 20 years from initial filing as a research discovery) led to the appearance of “generic” medicines. Generics medicines are those that have exactly the same active ingredients as the original brand, and compete on price.
Why it is important in our society to know what teratogen is, and some ways to prevent this birth defect in our society. Teratogen is a agent that disturbs the development of an embryo. Well, what exactly causes these disturbances in the embryo? By taking medicine during pregnancy, medicine prescribe to new mothers can cause abnormality in pregnancy. Although many women take medications during pregnancy, the medicine prescribe can be harmful. A example may be a woman during pregnancy comes across morning sickness; therefore, she may ask her doctor to prescribe medicine to treat her morning sickness. A common medicine to take during the 60's was thalidomide. However, over the years researchers found that thalidomide caused partial absence
Effects may vary depending on family structure, manifesting differently in individual family members; According to the National Center on Addiction and Substance Abuse both alcohol and drugs can have dramatic negative effects on a developing fetus. They have been linked with premature birth, decreased head circumference, brain functioning difficulties and low
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