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The Evolution Of Eugenics

Decent Essays

From evaluating the history that eugenics has imposed, its negative practice has been marked in ways of unrighteous holocaust and genocides worldwide. The word “eugenics” has been worldly defined and seen as the destruction of undesirable traits, in all reality people. However, the practice of altering or ridding of specific genes or minority group has changed through the evolution of time. Subcategorizing, eugenics has modernized and has advanced to the use of prenatal screenings, intentional selective breeding within agriculture, gene therapy, and possible human genetic engineering. Both articles that will be discussed, centralizes around the idea of genome sequencing. Specifically by focusing on the discovery of specific variant traits …show more content…

Covered by the Pan-African array, genotypes for approximately 2,176,716 SNPs were extracted from the 1000 Genomes Project Phase I data to be used for examination. The selection and observation of these allele frequencies were aimed to find ancestry-informative markers. Calculation of the Shannon Information Content (SIC), which took mutual information content and found the fundamental limits of each SNP, was obtained with the CEU and YRI samples. These AIMs then went through another selective process based on linkage disequilibrium (ID) to accept and reject SNPs. Based on the SIC, the highest ranked SNP was selected as an AIM candidate which concluded to 8 AIM candidates in a 4 cm region. To avoid overpopulation of markers, SNPs within a 0.25 cm region of the selected candidates were omitted and, by this system it ensured good coverage across the entire genome. Using the ANCESTRYMAP, the significance, quality and informative value of the AIMs were further analyzed at each SNP to measure uncertainty in ancestry interference at a specific locus. Detected AIMs were identified later to be conferred with other previously published samples. This comparison is shown in Figure 1C where the previously published samples were generalized around 0.1-0.12 proportion of variance explained (PVE) of pc1 ranging past 80

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