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The Flu is an Imminent Pandemic Essay

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Flu: The Imminent Pandemic

Influenza is an everyday disease that affects thousands worldwide. Despite its reputation as a mundane sickness, the flu (especially the avian flu) is widely touted by experts as the propagator of the next deadly pandemic. The secret to this virus’ lethality is its antigenic shifting, leading to increased virulence and transmission factors. If one strain of a super flu begins circulating, millions of lives and billions of dollars will be lost. Only by preparing a national and worldwide response to this threat will we be able to combat this imminent pandemic.

Deadlier than the Black Death, more lethal than nuclear warfare -- this is the modus operandi of the pathogenic virus alphainfluenzavirus …show more content…

Yet the flu is still a threat to humans, even in countries with access to excellent medical care. Why? Although yearly vaccines prevent many people from succumbing the disease, the flu virus can go through what is called an antigenic shift – one strain of the flu can jump between two different species, go through an intermediate host to another species, or genetically mix when two strains meet in the same cell (CNN 2). To give one example, let’s say a common human strain (H3N2) finds a human cell and uses its hemagglutinin proteins to infiltrate it. Another strain that infects birds, such as H5N1, enters the same cell. These two sets of genetic material mix to yield a new strain, which may inherit the transmission and severity factors from both parent strains to produce a new virulent virus in humans (CNN 3). This is how zoonotic strains of pathogens enter the human pool of diseases. If we see this happen with a strain of avian flu, the consequences will be overwhelming.
The impact of seasonal influenza is already severely underestimated, killing between a quarter to a half a million people each year and costing billions of dollars in productivity (Wilschut 17). With one strain of the super flu, we could be facing a worldwide catastrophe. A typical pandemic occurs in multi-year waves, beginning with a mutation in the original virus and spreading into subsequent milder cycles of disease,

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