Flu: The Imminent Pandemic
Influenza is an everyday disease that affects thousands worldwide. Despite its reputation as a mundane sickness, the flu (especially the avian flu) is widely touted by experts as the propagator of the next deadly pandemic. The secret to this virus’ lethality is its antigenic shifting, leading to increased virulence and transmission factors. If one strain of a super flu begins circulating, millions of lives and billions of dollars will be lost. Only by preparing a national and worldwide response to this threat will we be able to combat this imminent pandemic.
Deadlier than the Black Death, more lethal than nuclear warfare -- this is the modus operandi of the pathogenic virus alphainfluenzavirus
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Yet the flu is still a threat to humans, even in countries with access to excellent medical care. Why? Although yearly vaccines prevent many people from succumbing the disease, the flu virus can go through what is called an antigenic shift – one strain of the flu can jump between two different species, go through an intermediate host to another species, or genetically mix when two strains meet in the same cell (CNN 2). To give one example, let’s say a common human strain (H3N2) finds a human cell and uses its hemagglutinin proteins to infiltrate it. Another strain that infects birds, such as H5N1, enters the same cell. These two sets of genetic material mix to yield a new strain, which may inherit the transmission and severity factors from both parent strains to produce a new virulent virus in humans (CNN 3). This is how zoonotic strains of pathogens enter the human pool of diseases. If we see this happen with a strain of avian flu, the consequences will be overwhelming.
The impact of seasonal influenza is already severely underestimated, killing between a quarter to a half a million people each year and costing billions of dollars in productivity (Wilschut 17). With one strain of the super flu, we could be facing a worldwide catastrophe. A typical pandemic occurs in multi-year waves, beginning with a mutation in the original virus and spreading into subsequent milder cycles of disease,
In two years between 1918 and 1919, A pandemic of influenza swept mercilessly over the planet, killing millions which stood in its path. Miraculously, the exact origin of the pandemic is unclear. What is exceedingly clear, however, is that often the actions of man aided in the spread of the virus, whether due to inadvertent endangerment, close quarters, religious principles, or failure to recognize the true threat that influenza posed.
Throughout the history, influenza viruses have caused several pandemics or global epidemics, killing many people. For example, the influenza strike in 1918 to 1919 infected an estimated 500 million people worldwide, which is one-third of the planet’s population at the time and killed an estimated 20 million to 50 million people. More than 25 percentage of the U.S. population were affected, and caused 675,000 deaths in U.S during the pandemic.(History, 2015). There were no effective treatments for this type of influenza and no available vaccines can prevent its spread during the period. (History, 2015) U.S government required general population to wear masks and other protective equipments in public areas, and many public places also closed due to the influenza strike. Health care providers tried everything they knew to save people, but none shows any evidence of effects. (National Center for Biotechnology Information [NCBI], 2015). Scientists found out that the influenza virus had invaded their lungs and caused pneumonia, which made so many people died from the pandemic (History,2015). Another influenza strike happened
One of the most virulent strains of influenza in history ravaged the world and decimated the populations around the world. Present during World War I, the 1918 strain of pandemic influenza found many opportunities to spread through the war. At the time, science wasn’t advanced enough to study the virus, much less find a cure; medical personnel were helpless when it came to fighting the disease, and so the flu went on to infect millions and kill at a rate 25 times higher than the standard.
Every year, millions of people start talking about the influenza virus and getting their vaccines as the flu season approaches, which starts around the October-November period and reaches its peak between December and March. Therefore, public health officials around the world- and in the U.S in particular- are constantly challenged by properly preparing for the annual influenza dilemma, given that this viruses, and other respiratory viruses, are a serious health threat to the U.S population and the world as a whole. Furthermore, what makes the influenza virus even more challenging to control is that it can mutate rapidly and reassort to form new strains, having the ability to reside in multiple animal hosts. In fact, many scientists and researchers have been doing in-depth intensive research so as to understand the mechanism behind this unique characteristic of the virus, try to find new ways to control it, and explore different areas of protection and vaccination.
This influenza occurred at the latter point of “World War 1” coming at a vulnerable time for the world. Many people have already died due to the war, and many resources and money has already been consumed. So when the pandemic hit, it hit with a charge that left a great wound in the economy and health of the people not just in the U.S. but the world. People responded by taking more precautions in health and safety, and took radical response in the exterminating of animal populations.
Infectious epidemics and pandemics have happened all through mankind's history. “They remain the prime cause of death worldwide and will not be conquered during our lifetimes.” The flu of 1918 was one of the deadliest epidemics in history. “It infected an estimated 500 million people worldwide–about one-third of the planet’s population at the time–and killed an estimated 20 million to 50 million victims. More than 25 percent of the U.S. population became sick, and some 675,000 Americans died during the pandemic.” No one knew how the virus spread, there were no antibiotics to fight it, and no flu shots to prevent it. In the final year of World War I, it struck terror in the hearts of people all across Europe and left more death in its wake than the combined military actions of the combatants. “It killed more Americans in a few months than World War I, World War II, the Korean War, and the
This new influenza baffled researchers and doctors everywhere. Up to this point, all viral diseases has spread prominently throughout heavily populated areas and into the lungs of the very young, very old, or sickly. On the contrary, the Influenza of 1918 swept through the Midwest and preyed on the
Influenza, an innocent little virus that annually comes and goes, has always been a part of people’s lives. Knowing this, one would not believe that it has caused not one, not two, but three pandemics and is on its way to causing a fourth! The Spanish flu of 1918, the Asian flu of 1957, and the Hong Kong
Most people perceive “the flu” to be a common (not a big deal) illness, but they overlook the 20,000 deaths and over 100,000 hospitalizations nationwide.
Avian influenza is a disease that has been wreaking havoc on human populations since the 16th century. With the recent outbreak in 1997 of a new H5N1 avian flu subtype, the world has begun preparing for a pandemic by looking upon its past affects. In the 20th Century, the world witnessed three pandemics in the years of 1918, 1957, and 1968. In 1918 no vaccine, antibiotic, or clear recognition of the disease was known. Killing over 40 million in less than a year, the H1N1 strain ingrained a deep and lasting fear of the virus throughout the world. Though 1957 and 1968 brought on milder pandemics, they still killed an estimated 3 million people and presented a new
Study's show that it's highly unlikely that a influenza pandemic like the one in 1918 and 1919 is possible. The flu pandemic in 1918 and 1919,took more than 20 million people's lives in the world. According to the CDC, flu viruses are constantly changing and mutating which is why scientists can't develop a life long vaccine. According to experts they say that a flu pandemic would have a even greater impact on humanity than anything else currently happening in the world. Scientists also say that it's very rare that a flu pandemic will happen but, it's likely that their will be another one, and if there is it will be even bigger.Scientists are currently developing a vaccine just incase a pandemic were to happen. Doctors say if we were
According to Healthy People 2020 a goal of theirs is to “increase immunization rates and reduce preventable infections.” The influenza virus is one of these preventable infections, which can cause serious harm to patients. The influenza virus is known as the “flu.” Everyone in his or her life has had some experience with the flu, whether that is himself or herself or a family member. What if there was a way to ensure people from contracting a strain of the influenza virus? Well, thanks to technology and medical research there is.
The records and prediction of the world health organization for the number of people that would be infected by the pandemic in the near future.
Influenza is a virus that is transmitted mainly via airborne process, which is one of the fastest mode of transmission. It is transmitted though airborne due to symptoms such as coughing and sneezing of the host (the infected). The host sneezes and coughs, influenza can easily be transmitted the agent via droplets and small microorganism, therefore entering the uninfected though the respiratory system (mouth and nasal) (WHO, 2016). Another way the virus can lead to pandemic, is due to the fact that the number of human and animals continue to grow and interact. Thus, the pandemic of influenza type A is possible. This mode of transmission is both and; the airborne (respiratory system) and physically (hand contamination). The customarily begins in rural areas (farms) as the virus can be found in hosts such as horses, pigs, chickens and birds. There has been an undetected interchange of the disease among animals and humans in rural environments which then eventually grows to become a global pandemic (Webster, RG & Monto, AS et al 2013, Textbook of influenza). The virus may continue to spread physically due to hand contamination in public; these may include door handles, public transport and other hand held hold objects. The last mode of transmission is genetically, this may then lead to asthma or even death (WHO,
The world has experienced a total of four pandemics within the twentieth century. These pandemics, as horrific and deadly as they are, have brought so much more positive advances to our health care system and how we prepare for biological threats. Although we are in the twenty-first century and we have advanced so far in healthcare, there is still the possibility of a deadly pandemic.