In the early 1970’s, scientists in Japan and the United States began to study animal retroviruses to gain further knowledge about viruses that caused leukemia. Although animal retroviruses existed in non-human primates, it was believed that human retroviruses did not exist. However, after the T-cell lymphtropic virus was isolated from a patient with cutaneous T-cell lymphoma, the human T-cell leukemia/lymphoma virus (HTLV) became the first human retrovirus discovered and marked the beginning of scientific milestones.
Since the initial discovery of HTLV in 1980, there have been 7 HTLV subtypes that have been established, the Human immunodeficiency virus (HIV) was discovered and reclassified under the Lentivirus genus after previously being classified as a member of the HTLV family, and research has been conducted on the association of oncological diseases, the most prominent ones being Adult T-cell Leukemia/Lymphoma (ATL/ATLL), and other sexually transmitted infectious diseases with HTLV.
HTLV is present throughout the world in clusters, but it is highly endemic Japan, sub-Saharan Africa, Central & South America, the Caribbean islands, the Middle East, and Australo-Melanesia (2 & cdnlink). In North America and Europe, there is medium prevalence of the virus and it is suspected that the population of those infected are comprised of individuals linked to immigrants, children of immigrants, sex workers, and injection drug users (Medscape) ( cdnlink). Although researchers
CD4 is a glycoprotein found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. HIV infects cells of the immune system called T lymphocytes (T cells) and macrophages. HIV has an envelope and contains two copies of single-stranded RNA as the genome. Within the viral capsid are important viral enzymes called reverse transcriptase, integrase, and protease. The HIV virus has a spike protein that is called gp120, and the host cell receptor is CD4+. HIV belongs to a class of viruses called retroviruses. Retroviruses are RNA viruses, and to replicate or reproduce, they must make a DNA copy of their RNA through transcription and translation. It is the DNA genes that allow the
Lentiviruses similar to HIV have been found in a variety of primate species, and some of these are associated with a disease process called simian AIDS. Unlike other retroviruses, the primate lentiviruses are not transmitted through the germ line, and no endogenous copies of the virus exist in the genome of susceptible species.[23]
Typing Template for APA Papers: A Sample of Proper Formatting for the APA 6th Edition Sheela Jose
The acquired immunodeficiency syndrome (AIDS), which results form an infection called the human immunodeficiency syndrome virus (HIV) is a global epidemic that has taken numerous amounts of lives. There are two forms of HIV that are linked to AIDS, HIV-1 and HIV-2 (Crooks, Baur 460). HIV-1 is a virus that is constantly mutating and it is the first human immunodeficiency virus to be recognized as the leading cause of AIDS world wide, then we have HIV-2, which only occurs in some African countries (Crooks, Baur 460). In the 1980s the number of AIDS cases in the United States grew rapidly each year and eventually began to stabilize.
To be a retrovirus is not the same as a virus. HIV is a retrovirus and it is classified as this because HIV’s genetic information is being enclosed by RNA instead of DNA. HIV targets a specific cell within the immune system and those are the T cells or also known as CD4+ cells. HIV causes immune dysfunction by destroying these cells. HIV contains a glycoprotein, called gp120 that is vital for the virus to enter the T cell. It attaches to the surface, called the CD4+. As it attaches, the retrovirus’ membrane fuses to the lymphocyte cell membrane, therefore gaining entry into the cell.
It has been over 30 years since the first known cases of HIV (human immunodeficiency virus) which is the virus that causes AIDS (acquired immune deficiency syndrome) was reported. HIV attacks and disables the body 's immune system. The virus attacks, the T lymphocyte (T cell), a type of white blood cell. Formed in the bone marrow the T cell helps the body fight off germs and diseases. Once HIV enters the body, it attacks this cell, copies itself and destroys the cell. Being HIV-positive indicates that a person has been infected with the human immunodeficiency virus but does not yet have AIDS. After the white blood cell is destroyed, the virus moves on to the next healthy cell.
Human immunodeficiency Virus (HIV) is one of the most important health challenges in the world, because it can be preventive. In the United States over 1.2 million people are infected with HIV, and roughly 1 in 5 people are unaware they are infected (CDC, 2014) One of the best and most effective ways to reduce the spread of the virus is by creating HIV awareness, by implementing intervention programs in high risk HIV communities. This paper will provide an overall view of HIV, risk factors/health behaviors and analysis on HIV intervention programs, and the responsibilities of health educators.
Human Immunodeficiency Virus (HIV) is a fairly common diagnosis with an estimated 1.1 million people in the United stated who carry the infection and is predominantly seen in homosexual Caucasian and black males.1 Prognosis for individuals with HIV is vastly different and is dependent on many different variables. The Center for Disease and Control (CDC) has classified the HIV virus into 3 stages based on the symptoms and the pathological progression of the virus. The first stage of the virus lasts usually one to four weeks, which presents with similar symptoms of mononucleosis (2 p 367). Stage two of the virus roughly lasts about ten years, at which point the CD4+ t cell levels drop to around 1000 cells/microliter (2 p367). During the final stage, stage 3 occurs when the CD4+ T cells levels drop to 200 cells/microliter, and the person is now infected with AIDS and the progression of the infection may be very rapid (2 p367). Ultimately, the human immunodeficiency virus or HIV is a complex immune virus that is capable of destroying ones immune system, leaving their body defenseless.
Adults are not the only population affected by human immunodeficiency virus (HIV). Children are also affected by this virus. According to the Center for Disease Control and Prevention (2013), in the United States, there is more than a 90% decline in children who are infected with HIV prenatally since the mid-1990s. This is due to HIV testing and preventive interventions. The most common route of HIV infection in children is through perinatal transmission. Perinatal transmission is when a mother passes the infection to her baby. This transmission is through labor and delivery, breastfeeding, or during pregnancy (CDC, 2013).
HIV (Human immunodeficiency virus) is a lentivirus that results in AIDS (acquired immunodeficiency syndrome). HIV attacks and destroys CD4 helper lymphocyte cells - a specific type of immune system cell. As a result, the body has a harder time fighting off other infections, making minor illnesses more severe. The virus will go further to use those CD4 cells to create more of the virus. Once so many CD4 cells have been destroyed, HIV will become AIDS.
Societies have been devastated by a number of epidemiological outbreaks, but few diseases have been as antagonistic as the human immunodeficiency virus (HIV). The global transmission of this disease has been perpetuated by the ease of long distance travel and immigration (Magis-Rodriguez, 2004; Xu et al., 2014). Throughout the past 35 years the course of HIV and other sexually transmitted infections (STIs), as well as patterns of immigration, have changed immensely. Given the increase in both HIV and immigration, specifically in North Carolina (NC), this dissertation will focus mostly on changes, concerns, and strengths pertaining to the screening and treatment for HIV among Latino immigrants in NC. The
HIV, the Human Immunodeficiency Virus, was first discovered by CDC in 1981 [3], then described as HTLV-III in 1983 and was later changed into its current name. Ever since its emergence, this virus has caused millions of infections throughout the world, with most of the cases originating in the African region [1]. This retrovirus has made it difficult in the past for scientists to treat it since it changes its RNA once inside the cell to DNA, through the enzyme reverse transcriptase, and keeps changing its genetic information making it difficult to target a specific genome. The main concern of HIV is the development into AIDS, Acquired Immunodeficiency Disorder, which targets the body’s own T-cells through targeting the CD4 and co-receptors leading to various opportunistic infections and, eventually, death.
There are many different theories about how humans acquired Human Immunodeficiency Virus (HIV), but the CDC and WHO agree that it was likely passed from a chimp to a human in the 1930s or 1940s while the humans were hunting. The humans became exposed to chimpanzee blood during slaughter and the blood contained Simian Immunodeficiency Virus (SIV). SIV doesn’t infect humans and HIV doesn’t infect chimpanzees, but it is thought that eventually SIV adapted to HIV in humans. (I Know HIV, 2010)
Human Immunodeficiency Virus (HIV) is a retrovirus responsible for the acquisition of HIV infection which leads to the development of acquired immunodeficiency syndrome (AIDS). HIV targets cells that are part of the human immune system such as CD4+ T cells, macrophages and dendritic cells which results in the levels of these cells falling dangerously low as they are exterminated via different mechanisms. Such mechanisms typically involve the induction of signaling cascades that result in 'self-killing' protocols being executed by the cell, as well as becoming targets for direct killing of other cytotoxic cells in the immune system. As HIV is a lentivirus it contains two single-stranded, positive sense, RNA molecules each coding nine viral
The presence of a virus similar to Human Immunodeficiency Virus (HIV) was first identified in a species of chimpanzee in Africa and researchers believed contact with an infected ape 's blood to be the source of its transmission to humans. According to studies, this transmission may have occurred in the late 1800s. As years passed, the virus gradually swept across Africa and later into other regions throughout the world[1]. HIV, an infectious disease, tends to advance through body fluids such as blood, semen or breast milk[2] and attacks the immune system. As it progresses, it damages immune cells impairing the immune system in protecting against infections and diseases resulting in AIDS (acquired immunodeficiency syndrome).