When doing the sequence alignment, using BLAST, the sequences were confirmed to be those of the eight species. In other words the sequecnes were confirmed to be from Homo sapiens sapiens (modern human), Homo sapiens neanderthalensis (Neanderthal), Pan troglodytes (chimpanzee), Pan paniscus (bonobo), Gorilla gorilla (gorilla), Pongo abelii (Sumatran orangutan), Pongo pygmaeus (Bornean orangutan), and Hylobates lar (gibbon). Using BLAST, we were also able to confirm that the species were closely related since similarities were 100% or 99% for mitochondrial 16s rRNA and 100%, 99% and 96% for the mtDNA control region. After the sequences of the eight species were aligned, they were used to create a “Maximum Likelihood Estimate of …show more content…
For instance, in the mitochondrial 16s rRNA, when using the MP method, the clade containing Pan paniscus, Pongo pygmaeus, and Pongo abelii appear as a monophyletic clade 99% of bootstrap replication times (Figure 11A). However, when using the ME method, the clade contains Hylobates lar instead of Pan paniscus. Thus, the clade containing Hylobates lar, Pongo pygmaeus, and Pongo abelii appear as a monophyletic clade 98% of bootstrap replications (Figure 11A). The similarities between species was further supported by the skull measurements.
Conclusion By creating the phylogeny trees, based on the mitochondrial 16s rRNA and mtDNA control region makers, using MP and ME methods, we were able to determine the relationship between the eight primates. For instance, in the MP phylogeny based tree for mitochondrial 16s rRNA, modern humans and Neanderthal form a sister taxa that is more closely related to chimpanzee (Figure 11.3A). Moreover, MP and ME phylogeny based trees for mitochondrial 16s rRNA did support the hypothesis that modern humans and Neanderthals were the most closely related species when compared to the other six species (Figure 11.3A). However, the MP and ME phylogeny trees for mtDNA control region do not support this hypothesis since modern humans formed a sister taxa with chimpanzee while Neanderthal formed a sister taxa with bonobo (figure 11.3B). Furthermore, none of the trees support the second hypothesis
According to my observation, even though Chimpanzee, and Gorilla are similar, they differ in many other ways when we go deeper in physical, and behavioral traits. However, both species also share the majority part of their DNA with Humans. Based on some reliable researches, some scientists realized that humans did not come from apes but instead shared common ancestors. As a matter of fact, humans and Primates are different, but share most of their genome, explaining why we found some similar patterns of behavior among humans, and
The fossils which passed the amino acid tests were called “transitional” elements between the two species. They represented a part of Europe where the Neanderthals and early humans would have more than likely encountered each other. The same DNA sequence was found in Neanderthals and early humans, but also in ancient cave bears from Croatia and Austria. This made the researchers skeptical of their findings and decided to test for mtDNA stands. When the fossils were further analyzed, the researchers found that the mtDNA embedded in the Neanderthal fossils was of a different strain than that in the early humans, which was of course, different from that of the ancient cave bears.
“All four Neanderthals yielded the mtDNA sequences similar to those previously determined from Neanderthal individuals, whereas none of the five early modern humans contained such mtDNA sequences. In combination with current mtDNA data, this excludes any large genetic contribution by Neanderthals to early modern humans, but does not rule out the possibility of a smaller contribution” (Serre, 16 March 2004).
The first true evolution of primates goes all the way back to 55 million years ago.. Primates descend in two orders, Stepsirrhini and Haplorrhini. The Stepsirhines were the first of the suborders to unfold. That term is identical with prosimians. Prosimians are defined as a “pre-monkey” in Latin(anthro.palomar.edu). Evidence was not shown until the 20th century of prosimians evolving before the monkey. A stepsirhine that is still alive and studied today are lemurs. Lemurs are the oldest ancestors of monkeys, apes, and humans. There is research of a Lemur’s past and present habitats, discovered theorists, predators, diet, life expectancy, large number of subspecies, and fossils collected about Lemurs.
The eight primates whose sequences were used are: Homo sapiens sapiens (modern human), Homo sapiens neanderthalensis (Neanderthal), Pan troglodytes (chimpanzee), Pan paniscus (bonobo), Gorilla gorilla (gorilla), Pongo abelii (Sumatran orangutan), Pongo pygmaeus (Bornean orangutan), and Hylobates lar (gibbon). Based on morphological similarities, it is hypothesized that Neanderthal is the most closely related species to humans. For instance, both species walk up right, have large brains, were able to develop and create tools and had spoken language—although more research is still needed to say for certain that Neanderthals did have spoken language. Additionally, it is also hypothesized that modern human and Neanderthal are both more closely related to the sister group of bonobo and chimpanzee, then to gorilla, then to the sister taxa of Sumatran orangutan and Bornean orangutan, and lastly the gibbon (the outgroup of this data). Hence, by developing the order of these eight primates through genetic data and phylogenetic character analysis, we can gain a new insight into the evolution of
According to the report of the U.S. Department of Health and Human Services National Institute of Health presented in 2005, chimpanzees share 96% of the human gene sequence. It allows to draw a conclusion that humans and chimpanzees are very closely related to each other, and this relation is great than between humans and other species, such as gorillas or orangutans. Regarding evolution of humans, it is also interesting to note that according to taxonomists originally both humans and apes belonged to the same superfamily of primates, but later they were separated into families: humans - to Hominidae, and apes – to Pongidae. (Steffof,
"New standards pointed out about that discrepancies in a molecular evidence has challenged the evolutionary theory of common ancestry of all living things and that whether microevolution can be extrapolated to explain macro evolutionary changes is controversial".(LeBeau, 2007)
Observe skull sample and record nasal root, lower border of nasal aperture, orbital shape, malar tubercle, dental shape, and lingual side of incisors. Compare your observations with the information in lab book’s (table 8.3) characteristics to determine ancestry of the
We often have misconceptions whether we share some DNA with common ancestors and we now have the ability to fully understand that we do. When people first meet, they often ask where we are from and respond with an ethnic background, but do not take the time to realize how we came to be. Not many think back to the time where modern humans truly became modern humans and see if we even shared DNA with them. Not many like to admit that they share DNA with those who were “clueless and lived in caves”. One of our common ancestor, Homo neanderthalensis, were found around 400,000 to 40,000 years ago in most of Europe and Southwest Asia (Smithsonian National Museum of Natural History, 2016). Upon discovery, scientists were able to use the combination
However, the ME for the mitochondrial 16s rRNA shows that gorilla is more closely related to the chimpanzee and the bonobo, when compared to the other primates (Figure 11.3A). Furthermore, all of the four trees produced show that modern humans and Neanderthals appear as a monophyletic clade 100% of bootstrap replication times which supports the first hypothesis stating that Neanderthals would be the closest relatives to modern humans, when compared to the other primates (Figure 11.3A, 11.3B).
To create the phylogenetic tree we used the program Geneious which allows for various analyses within the single program. We used two datasets to start the analysis; the first an unknown file containing the 12S sequences for the three Rwanda samples and the second containing the 12S Sequences for the eight primate species. After opening the program we set up a
2. It can be concluded that both hominins and modern apes share flat face with forward facing eyes and molars present. The Phylogenetic Tree shows that the modern apes diverged from hominins. This implies that modern apes and hominins share a same ancestor, but early hominins did not evolve from modern apes. The closest relative of human (Homo sapiens) is Homo neanderthalensis. We share many characteristics, such as chain, large cranium and similar width of dental arcade to the length. One of differences is Homo neanderthalensis has Supraorbital bow, not human does not.
The author of this book, Brian Sykes, presents his discoveries regarding the possibility that all humans branched from seven main clans. The book focuses mostly on the ancestors of Europe and the East. He supports his findings with the evidence of mitochondrial DNA. Sykes explains that mitochondrial DNA can be traced back to the original matriarchal ancestors. His findings showed that people from certain parts of the world had mitochondrial DNA that related more closely to one of the seven clans. Each of the clans has some defining characteristics which make it an more reliable source of lineage rather than ordinary DNA, which has become muddled throughout the generations. He presents the women of each clan with enigmatic names: Helena, Xenia, Ursula, Velda, Jasmine, Tara, and Katrine. He also explains the advances in genetic science, which he uses to explain the studies presented. The studies regarded Polynesian islanders, the Romanovs, the hunter-gatherers in Europe, and many others.
During the 1980s, three specialists, Allan Wilson, Rebecca Cann and Mark Stoneking, worked together on another theory that supports Charles Darwin's speculation, the “Mitochondrial Eve” hypothesis. In these tests, the scientists solemnly focused on mitochondrial DNA, human genes that lay within the cell and are passed from mother to child. These genes allow mutation, as they mutate quickly for adaptation, thus allowing those studying to find and track changes during short time periods. By focusing on these genes and comparing their differences, the three scientists were able to create a hypothesis about the time and place when modern humans began to evolve. According to their findings, they believe that modern humans are decentants from a single population, while earlier humans e.g. Neandertals and Homo erectus, had become extinct. Furthermore, the team compared the DNA of numerous people of differerent ethnic backgrounds and concluded that all humans did indeed evolve from 'one mother' in Africa about 150,000 years ago.
Another topic that interested me is how the Neanderthals are our closest extinct human relatives. They have a very similar build compared to us today. I have learned that Neanderthals are a little bit shorter then most of us. How the scientist recovered DNA from remains from the Neanderthals, and they analyzed it. The scientists have