EMPHYSEMA Defined as the permanent enlargement of the alveoli. Typically, the alveoli are tiny, grape-like clusters that allow for greater surface area for gas exchange. In emphysema, the grape-like clusters are destroyed, leaving behind one large “bleb” alveoli that is difficult to ventilate without increased air-trapping. Once the inhaled air becomes trapped in the bleb, additional oxygen-rich air is unable to enter the bleb. CHRONIC BRONCHITIS Defined as a productive cough that last for at least three months in each of at least 2 consecutive years. All other reasons for a productive cough, such as pneumonia, are ruled out prior to diagnosis of bronchitis. Risk factors: • Cigarette smoking o Especially in people over the age of 40 with 10 or more pack-years. o Smoking causes cell hyperplasia especially in the goblet cells. This leads to increased mucus production. Cell hyperplasia also causes the diameter of the airways to shrink making it harder to clear the excess amounts of mucus being produced by the hyperplastic goblet cells. o Cigarette smoke also paralyzes cilia necessary to move mucus up the airways. With enough exposure, the cilia can actually be destroyed. o Smoking also can break down the grape-like clusters of the alveoli leading to blebs that are hard to ventilate and lead to air-trapping of CO2 rich air. o Smoke can also cause chronic inflammation that leads to airway remodeling due to scarring. o Smoking can also constantly irritate the cells of
Cigarette smoke when inhaled and exhaled release toxic particles and vapors. When the cigarette smoke enters the nose, to the nasal cavity, paranasal sinus, into the larnyx, esophagus and onward through the body. I want to stop and go back to the beginning of smoke entry. The nose contains external nears or cilia. These cilia try to capture as much of these toxic particles and push them back towards the outside of the nose. Then these toxic particles move through the nasal cavity, up and around the paranasal sinuses, which contains the frontal, esthmoid, maxillary and sphenoid sinus. Let me explain a few fundamentals. The cilia, nasal cavity and paranasal sinuses help filter, warm and moisten the air you breath,
It also contains toxic gases and particles that may be damaging to the lungs. Marijuana smoking is associated with large airway inflammation, increased airway resistance, and lung hyperinflation, and regular marijuana smokers report more symptoms of chronic bronchitis than non-smokers. Smoking marijuana could reduce the respiratory system’s immune response, increasing the chances of respiratory infections, including pneumonia. One study found that frequent marijuana smokers used more sick days than other people, often because of respiratory illnesses. Marijuana affects your lungs greatly, especially if you smoke it. The Smoke from marijuana contains some of the same toxins, irritants and carcinogens that is to be found in tobacco smoke. The smoke of marijuana has been shown to injure the cell linings of the large airways, which explains why smoking marijuana leads to chronic cough, phlegm production, wheezing, and bronchitis. Another thing that has been found from smoking marijuana and the effects it has on your lungs is leaving air pockets in both lungs, between them, and in the chest wall. Smoking marijuana kills the first line of defense for your lungs which is killing the cells that help remove dust and germs, but only causing more mucus to be formed. All this may cause serious breathing problems. Not only does smoking marijuana greatly affect your respiratory system, but it
Emphysema affects the parenchyma of the lung through destruction of the alveolar walls, leading to permanent enlargement of air spaces distal to the
Contaminations, allergies and smoking can bring a certain kind of lung malady or lung issue.
Cigarette smoking leads to changes in the lung cells, which in turn, causes swelling and
It also contains toxic gases and particles that can damage the lungs. Marijuana smoking is associated with large airway inflammation, increased airway resistance, and lung hyperinflation, and regular marijuana smokers report more symptoms of chronic bronchitis than nonsmokers. Smoking marijuana may also reduce the respiratory system's immune response, increasing the likelihood of the user acquiring respiratory infections, including pneumonia. One study found that frequent marijuana smokers used more sick days than other people often due to respiratory
Smoking is able to ruin our lungs and (according to MayoClinic) other parts of our body
Environmental tobacco smoke increase the risk of respiratory infection such as bronchiolitis, middle ear infection, meningococcal infections, asthma attacks, sudden infant death syndrome, lung cancer and heart disease.
the epithelial lining of the airways becomes chronically inflamed and can peel away. The mucus-secreting cells in the large airways multiply and expand in number and size, increasing the viscosity and production of the mucus. The cilia are destroyed and the ability of the lungs to remove mucus is impaired.
Smoking is one of the main causes of Chronic Obstructive Pulmonary disease also called COPD. According to the World Health Organization (WHO) COPD is “a lung disease characterized by chronic obstruction of lung airflow that interferes with normal breathing and is not fully reversible”.(Chronic).
Briefly, epithelial cells, macrophages, and neutrophils in lungs are activated by cigarette smoke directly or by the releasing of damage-associated molecular patterns (DAMPs) indirectly, via oxidative stress or by inducing pattern recognition receptors (PRR) such as Toll-like receptors (TLRs) and purinergic receptors (P2X7 and P2Y2). Due to
In adults, acute bronchitis usually goes away within two weeks. Smoking, allergies, and asthma can make the condition worse. Repeated episodes of bronchitis may cause further lung problems.
The large particles in cigarette smoke, commonly known as “tar”, collect in the branching points of the lungs. The tar contains carcinogenic compounds that increase the risk of lung cancer. The small particles in cigarette smoke, including carcinogens, irritants, and corrosive chemicals, collect in the small air sacs in the lungs and damage them. These air sacs are where the blood absorbs oxygen from the air. When the small particles from the cigarette smoke are absorbed into the blood
comes from smoking is lung cancer. This type of cancer will weaken their lungs making it harder for
The simple smoke from a cigarette is more complex then it really looks. "Each time a person breaths in smoke about a million particles of very tiny complex materials are breathed in and only 20% of that is breathed out."(Hyde 1990) From these little millions of particles is the reason it causes problems for the human body. The main material in the some is nicotine. "Nicotine is an alkaloid poison found in