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The Plasmodium Parasite

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Abstract

This literature review addresses the life cycle of the Plasmodium parasite, the manipulation methods used by the parasite, and discusses some of the preventative methods against the disease. The Plasmodium parasite is the cause of the disease malaria, which is most prevalent in Africa however there have been cases all over the world. In 2012, 627,000 people died from malaria, the majority of which were children under the age of five. Its complex multi-stage life cycle makes it very difficult to treat, with symptoms synonymous with those of the flu, and relapses being extremely common. The fact that the life cycle is so complex in both species the parasite infects means that eradicating the disease altogether is almost …show more content…

Malaria is most prevalent in Sub-Saharan Africa, due to the favourable climate and lack of prevention and treatment methods. There are 5 different strains of the human malaria parasite; P.vivax, P.ovale, P.malariae, P.knowlesi, with the most aggressive and most lethal being P.falciparum. The parasite is transmitted via the vector female Anopheles Mosquitoes, the only known vector of the disease. A vector is an organism that the parasite relies on for its transmission. Malaria is only transmitted by females and not males, as females need the proteins in blood for the development of eggs.
The malaria parasites are some of the most wide spread parasites, with pervasiveness reaching 100%. The World Health Organisation (WHO) estimates the number of cases of Malaria in 2012 was 207 million, 627,000 of those resulting in death. 90% of the cases above occurred in sub-Saharan Africa. Malaria is present in more than 100 countries, the population of these countries making up 40% of the world’s overall population. The majority of the deaths occur in remote rural villages where they have a lack of medical facilities at a close and easy distance. Some people in a population are more at risk than others – for example pregnant women are more vulnerable due to the physiological strain of child bearing, as well as prenatal anaemia and low birth weight as are children, non-immune travellers,

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