Abstract
This literature review addresses the life cycle of the Plasmodium parasite, the manipulation methods used by the parasite, and discusses some of the preventative methods against the disease. The Plasmodium parasite is the cause of the disease malaria, which is most prevalent in Africa however there have been cases all over the world. In 2012, 627,000 people died from malaria, the majority of which were children under the age of five. Its complex multi-stage life cycle makes it very difficult to treat, with symptoms synonymous with those of the flu, and relapses being extremely common. The fact that the life cycle is so complex in both species the parasite infects means that eradicating the disease altogether is almost
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Malaria is most prevalent in Sub-Saharan Africa, due to the favourable climate and lack of prevention and treatment methods. There are 5 different strains of the human malaria parasite; P.vivax, P.ovale, P.malariae, P.knowlesi, with the most aggressive and most lethal being P.falciparum. The parasite is transmitted via the vector female Anopheles Mosquitoes, the only known vector of the disease. A vector is an organism that the parasite relies on for its transmission. Malaria is only transmitted by females and not males, as females need the proteins in blood for the development of eggs.
The malaria parasites are some of the most wide spread parasites, with pervasiveness reaching 100%. The World Health Organisation (WHO) estimates the number of cases of Malaria in 2012 was 207 million, 627,000 of those resulting in death. 90% of the cases above occurred in sub-Saharan Africa. Malaria is present in more than 100 countries, the population of these countries making up 40% of the world’s overall population. The majority of the deaths occur in remote rural villages where they have a lack of medical facilities at a close and easy distance. Some people in a population are more at risk than others – for example pregnant women are more vulnerable due to the physiological strain of child bearing, as well as prenatal anaemia and low birth weight as are children, non-immune travellers,
Malaria is a very contagious parasite transmitted through mosquitoes to humans. Those at risk are individuals living in areas conducive to the breeding of mosquitoes, especially those that allow the mosquitoes to complete their growth cycle. Everyone is at risk
Malaria infection is caused by parasitic protozoan plasmodium. Several species of malaria parasites exist but the most fatal known is plasmodium falciparum. It enters the liver and replicates itself by getting into the red blood cell and ripping its way out when fully matured. It was once thought that the US military got close to completely eradicating the vector mosquito through DDT (dichlorodiphenyltrichloroethane) and the parasitic plasmodium with vaccines until they discovered that both are capable of mutating and gained the ability to be resistant to any chemicals scientists could produce (Horizon, 2005).
Malaria (also called biduoterian fever, blackwater fever, falciparum malaria, plasmodium, Quartan malaria, and tertian malaria) is one of the most infectious and most common diseases in the world. This serious, sometimes-fatal disease is caused by a parasite that is carried by a certain species of mosquito called the Anopheles. It claims more lives every year than any other transmissible disease except tuberculosis. Every year, five hundred million adults and children (around nine percent of the world’s population) contract the disease and of these, one hundred million people die. Children are more susceptible to the disease than adults, and in Africa, where ninety percent of the world’s cases occur and where eighty percent of the cases
Malaria is spread by the female Anopheles mosquito.When the mosquito bites the malaria parasite is passed into the human bloodstream, infecting them and this works both ways, if a human has previously been given the parasite and a unaffected mosquito bites them, the mosquito will pick up the parasite and spread it further. For the mosquito to survive it the humidity must be high, and the temperature must be between 15°C and below 40°C. Stagnant pools of water allow the mosquito to live. It uses areas like marshes, lakes and river pools to breed. Increasing population growth can encourage people to live closer to affected areas that were previously avoided, such as close to river pools. Normally the
Malaria has been a huge problem among many developing nations over the past century. The amount of people in the entire world that die from malaria each year is between 700,000 and 2.7 million. 75% of these deaths are African children (Med. Letter on CDC & FDA, 2001). 90% of the malaria cases in the world are located in Sub-Saharan Africa. Once again, the majority of these deaths are of children (Randerson, 2002). The numbers speak for themselves. Malaria is a huge problem and needs to be dealt with immediately.
The plasmodium protist is the building block of one of the deadliest diseases called Malaria, spreading through the bloodstream diseasing organs one by one. Malaria kills around 500,000 to 700,000 people a year, and in 2012 there were 207 million cases of it around the world. This chain of infection, and even death is started through the transmission of the plasmodium protist. It all starts when a specific genus of mosquito makes contact with a human. This genus is called the female Anopheles mosquito. The plasmodium resides by its saliva gland, making an easy escape when the mosquito bites a human host. The plasmodium begins its journey traveling through
In areas where malaria thrives, human populations have been known to suffer in its clutches. Malaria is a tropical disease that causes thousands of deaths worldwide. However, a majority of malaria cases and deaths occur in Sub-Saharan Africa. The prevalence of malaria in African countries places a heavy burden on its people and affects all aspects of society. Considered both a consequence and a fundamental cause of poverty, malaria has a host of negative effects that hinder the growth and well-being of the African population.
Malaria is mostly affected in Africa due to combination of factors in that country. Due to their mosquito’s type and bacteria carrying. There local weather condition allows transmission to occur all year long. In most cases Malaria is less chance to cause death but if not diagnosed on time can lead to death especially in children.
Malaria. Our 130 million year old enemy. Malaria has been around since the dawn of time and just like the evolution of humans, the disease evolved over time (Malaria.com, 2011). Malaria is a life-threatening disease caused by a specific parasite called Plasmodium, and it is transmitted to people through the bites of an infected female Anopheles mosquito. Plasmodium is a unique parasite because of its structure-it is a single celled organism that multiples in our red blood cells (Canada.com, 2016). The Plasmodium parasite has 4 species which are known to cause the disease in humans, these being: P. Vivax, P. Falciparum, P. Ovale, and P. Malariae. Specifically, P. Vivax, and P. Falciparum are the 2 most common types of parasites to cause the
For example, 500 million people get infected by malaria annually (“Plasmodium” 1), with an even larger amount of deaths occurring as well. This can be shown when the article states: “This disease has been a problem for humans for millennia...the number of people who are actually infected is thought to be upwards of 500 millions people annually…the death toll of malaria is one to two million people each year”(“Plasmodium” 1). This shows the increasingly high infection number of those who have malaria, and the problem it has been for humanity. As well, malaria during pregnancy can host a variety of risks for both baby and mother, such as malnutrition of the fetus, low birth weight, or maternal death (Gomes 1). The author supports this by saying: “Scientific reports noted the effectiveness of the placental barrier...the danger of suboptimal nutrition of the fetus, congenital malaria, poor fetal development, low birth weight, premature interruption of pregnancy, and maternal death” (Gomes 1). This supports the numerous health risks taken by a woman who is pregnant, risking two lives by one disease. Therefore, the disease of malaria can have a negative impact on both the current generation of people who live in inadequate conditions, and the disease’ ability to impact the future generations as
Malaria is one of those diseases that have stood the test of time, and still of major concern in many regions of the world, especially in tropical areas. It is an intermittent and remittent fever caused by a protozoan parasite that invades red blood cells. Malaria affects approximately two hundred and fifty million people annually, with the morbidity burden felt most in the tropics. Children under the ages of five and pregnant women in Sub-Saharan Africa are the groups most affected by this disease. Malaria is the leading cause of death from parasitic infection worldwide, with approximately one million deaths each year. Most of these deaths occur in Africa, followed by South East Asia.
Malaria (also called biduoterian fever, blackwater fever, falciparum malaria, plasmodium, Quartan malaria, and tertian malaria) is one of the most infectious and most common diseases in the world. This serious, sometimes-fatal disease is caused by a parasite that is carried by a certain species of mosquito called the Anopheles. It claims more lives every year than any other transmissible disease except tuberculosis. Every year, five hundred million adults and children (around nine percent of the world's population) contract the disease and of these, one hundred million people die. Children are more susceptible to the disease than adults, and in Africa, where ninety percent of the world's cases occur and where eighty percent of the
About 3.3 billion people, that is about half of the world’s population are at risk of contracting malaria (figure 1). Every year there are 250 million cases of malaria, and nearly 1 million deaths. That amounts to 2,732 deaths per day. Out of those million people that die every year, 800,000 of them are African children under the age of 5. To control malaria three actions need to be taken: insecticides need to be used to decrease the vector population, people have to be educated as to how to prevent the vector from reproducing, and anti-malarial drugs need to be distributed. To understand the vector and what the vector is, scientists had to first discover what the parasite was and how it worked. It was not until the year 1880 that French Physician Charles Laveran discovered that Malaria was caused by a protozoan in the genus Plasmodium (Malaria, 2013)
Feasibility of computer-aided identification of the Plasmodium berghei parasite in the liver stage life cycle and the classification of the parasite phenotype
Malaria is one of the ten most common, yet deadly diseases in the world. It is a parasitic disease spread by the bite of Anopheles mosquito, which is active between dusk and dawn. Malaria occurs in over 100 countries and territories.