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Types Of Cancer Of The Uterus, Uterine Sarcomas And Endometrial Carcinomas

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There are two main types of cancer of the uterus, uterine sarcomas and endometrial carcinomas. Endometrium cancer begins when the tissues of the inner lining of the uterus (endometrium) begin to grow out of control.1 There are many subtypes of endometrial cancer based on the histology of the cells. Endometrial cancer is furthermore, graded based on how much the cancer forms and glands that have the similar morphology of healthy and normal endometrium glands.2 Endometrial Cancer primarily affects woman of postmenopausal age and some of the risk factors include, things that affect hormone levels, like taking estrogen after menopause, birth control pills, or tamoxifen; the number of menstrual cycles (over a lifetime), pregnancy, obesity, certain ovarian tumors, and polycystic ovarian syndrome, use of an intrauterine device, age, diet and exercise, diabetes, family history (having close relatives with endometrial or colorectal cancer, having been diagnosed with breast or ovarian cancer in the past, having been diagnosed with endometrial hyperplasia in the past and treatment with radiation therapy to the pelvis to treat another cancer. 3

The four basic treatments for endometrial cancer are surgery, radiation therapy, hormonal therapy and chemotherapy.4 Expanding on treatment, there is a growing body of evidence that suggests the anti-diabetic class, biguanides, may have effective anti-cancer properties against endometrial cancer. 2 The three drugs included in this class are

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