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Ventricular Fibrillation And Its Effects On The Heart

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Ventricular fibrillation (VF) is a life-threatening condition in which the signaling in the ventricles of the hearts is no longer coordinated. The loss of this coordinated signaling causes rapid, random and chaotic signaling leading to spasms of the ventricular walls. During VF, blood is not being circulated to the brains and the rest of the body and is therefore deprived of oxygen. This condition can be reversed by using a defibrillator, which sends an electric discharge of direct current to the victim (1). Improper signaling of electrical activity in the heart can also lead to a rapid heart rate. This type of tachycardia is called ventricular tachycardia (VT) and may lead to VF (Figure 1). Pulseless VT is also with defibrillation and VF and VT are both considered shockable heart rhythms (2,3).
A large and increasing proportion of patients presents with non-shockable rhythms in out-of-hospital cardiac arrest (OHCA). These non-shockable rhythms are pulseless electrical activity (PEA) and asystole. During PEA, a normal heart rhythm is observed on the electrocardiogram (ECG), but without cardiac output. Asystole is a condition without ventricular complexes. The heart muscles fail to contract due to the lack of cardiac electrical activity. Both PEA and asystole are treated with cardiopulmonary resuscitation (CPR) without defibrillation, combined with epinephrine administered intravenously (4). Non-shockable rhythms are associated with high mortality. The survival rates of PEA

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