. A patient rushed into a hospital complaining of severe pain and a burning sensation in his chest region. Doctors suspected it to be a case of gastric ulcer or a myocardial infarction. Hence, they immediately screened his blood serum for marker enzyme levels, where they found elevated levels of the LDH, (H4) isoform. Analyse the clinical condition of the patient.
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- A. Elastase is activated by trypsinB. Trypsinisactivatedbyelastase Which statement is correct? Proteolytic activation of chymotrypsin from chymotrypsinogen requires cleavage of four peptide bonds. Assume that any proteases can convert 100 substrates to 100 products. Activation of one enteropeptidase can eventually lead to formation of how many chymotrypsin proteins?explain why natural protease inhibitors (peptide extracts from the pancreas of cattle - aprotinin) can also arrest the destruction of pancreatic proteins, but often cause an allergic reaction.A six year old boy dies of heart failure. He had mental retardation, short stature, course facial features, corneal, clouding, a large tongue, short, broad fingers, and skeletal dysplasia. He was normal at birth, progressive mental, and physical deterioration began at age 6 month. Examination at autopsy shows cornary artery thickening, and a tracheal narrowing. The most likely cause of these abnormalities is a deficiency of which of the following enzymes? A) alpha 1 antitrypsin B) galactocerebrosidase C) glycogen phosphorylase D) alpha -L- iduronidase E) type IV Collagenase
- Which of the following caused your patient’s hyperglycemia?a. treatment for anaphylactic shock (systemic anaphylaxis)b. the presence of Glut-2 on beta cells in the pancreasc. the secretion of amylind. the presence of Glut-4 on adipose tissuee. hyponatremia1. State if true or false a. GLUT5 transporter carries fructose from the intestinal lumen into the enterocyte. b. Microbial enzymes can digest carbohydrates containing β–1,4 bondsIn healthy adults, the concentration of glucose in blood is approximately80 to 110 milligrams per deciliter (mg/dl). After a carbohydrate-richmeal, however, the concentration may spike to 140 mg/dl. Describe thehormonal action that returns blood glucose to normal.
- All of the following are true with respect to alpha-glucosidase inhibitor, except:A. It inhibits intestinal alpha-glucosidase B. It decreases enzymatic conversion of oligo- to monosaccharidesC. It lowers postprandial glucoseD. It causes gastrointestinal disturbances.E. It may cause development of hypertension.The small intestine catabolizes amino acids, producing signifi cant amounts of NH4+. Describe the metabolic fate of the NH4+.Greg Tobin mixes together three types of vitamintablets. Each Super Vim tablet contains, among other things,15 mg of niacin and 12 I.U. of vitamin E. The figures for aMultitab tablet are 20 mg and 15 I.U., and for a Mighty Mix are25 mg and 35 I.U. How many of each tablet are there if the totalnumber of tablets, total amount of niacin, and total amount ofvitamin E are as follows?a. 225 tablets, 4750 mg of niacin, and 5225 I.U. of vitamin Eb. 185 tablets, 3625 mg of niacin, and 3750 I.U. of vitamin Ec. 230 tablets, 4450 mg of niacin, and 4210 I.U. of vitamin E
- Discuss why the most effective oral rehydration therapy is water containing sodium and glucose instead of water alone or water with fructose.Ist this statement correct? Canagliflozin is therapeutically useful for managing type 2 diabetes because this drug decreases the renal clearance of glucose.Discuss the 3 mechanisms of abnormal carbohydrates metabolism that result in the development of ketone bodies in the urine and give examples of the condition to each.