. Dosage compensation is necessary because a. some regions of the genome contain more genes than others.b. genes near heterochromatin tend to be silenced. c. enhancers can activate transcription whether they are upstream or downstream of a gene. d. genes on the X chromosome have twice as many copies in females as in males

. Dosage compensation is necessary because a. some regions of the genome contain more genes than others.b. genes near heterochromatin tend to be silenced. c. enhancers can activate transcription whether they are upstream or downstream of a gene. d. genes on the X chromosome have twice as many copies in females as in males

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter14: Gene Regulation

Section: Chapter Questions

Problem 8TYU: Through alternative splicing, eukaryotes (a) reinforce gene inactivation (b) prevent transcription...

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Which of the following mutations could be appropriately describedas a position effect?A. A point mutation at the –10 position in the promoter regionprevents transcription. B. A translocation places the coding sequence for a muscle-specificgene next to an enhancer that is turned on in nerve cells.C. An inversion flips a gene from the long arm of chromosome 17(which is euchromatic) to the short arm (which isheterochromatic).
a) What is a gene promoter? b) What proteins bind to a promoter? c) What do those proteins do to control gene expression?
1)A. how do you read a sequence of DNA (template or non-template strand) to convert it an mRNA sequence and to a protein? B.How does chromatin remodeling regulate gene transcription? C. What are the major differences between gene expression in bacteria and eukaryotes D. How are non-coding regions involved in gene transcription? E. Explain how eukaryotic genes sometimes produce multiple protein products?
In one cell, gene C is expressed, whereas in another cell, geneC is inactive. After the cells are fused experimentally, both copiesof gene C are expressed. This observation could be explained bya. a cis-epigenetic mechanism.b. a trans-epigenetic mechanism.c. DNA methylation.d. both a and b.
Q. Which of the following describes the role of acetylation during the chromatin remodeling that accompanies gene expression? A. It adds an acetyl group to the DNA of a promoter sequence. B. It adds an acetyl group to the histone protecting the promoter region of a gene. C. It adds an acetyl group to the cyotsine nucleotides of DNA. D. It adds an acetyl group to the histone protecting the transcription unit of a gene.
If a mutation occurred in a control element sequence associated with a particular gene, which of the following would be a likely consequence of this? A. This mutation is not likely to affect the expression of the associated gene, because RNA polymerase does not bind to control elements. B. This will likely affect the expression of the associated gene because it will loosen the coiling of chromatin at this site. C. The expression of the associated gene will be affected because this change will result in a nonsense mutation. D. This mutation is not likely to affect the expression of the associated gene, since control elements are noncoding sequences. E. The associated gene's expression would likely be affected, since this mutation would change the ability of at least one transcription factor to bind.
During X inactivation, all but one gene get silenced on one X chromosome. Why does one gene escape the inactivation? A) That is the gene responsible for inactivating the others B) Two copies of that gene are needed in females, so both are active C) X inactivation is rarely complete, so occasionally one or two genes get activated by mistake D) That is the gene that encodes the methyltransferase needed to methylate the genome.
Can one transcription factor sometimes act as a repressor and sometimes act as an activator? a. Yes, but it depends on where the transcription factor binds in the promoter b. Yes, but it depends on other proteins that might act with the transcription factor c. No, transcription factors are always either activators or repressors d. Yes, but only if a mutation happens
A genon wide analyst of human genome indicated that approximately 1500 genes encoded transcription factors that are important for sequence specific gene expression. based on this information approximately what percentage of the protein coding genes in human belong to the transcription factors? A. 15% B. 5% C. 7.5% D.1.5%
Your investors are concerned that the GasP protein might not be sufficiently produced under normal laboratory conditions. They suggest controlling the transcription of the gasP gene using a chemical that will “trigger” its transcription. a. What type of promoter could be used? b. What chemical will you use to control transcription? c. How does this method of control work?
Through alternative splicing, eukaryotes (a) reinforce gene inactivation (b) prevent transcription of heterochromatin (c) produce related but different proteins in different tissues (d) amplify genes to meet the requirement of high levels of a gene product (e) bind transcription factors to enhancers to activate transcription
In eukaryotes, chromatin remodeling plays an important role is gene regulation. This is because a. repositioning of the nucleosomes makes DNA accessible to transcription regulatory proteins b. the nucleosomes contain important regulatory regions c. chromatin remodeling activates gene expression d. chromatin remodeling represses gene expression