0200 7 The anticancer drug paclitaxel (Taxol), derived from the Pacific Yew, has many effects on mitosis. One of its most powerful effects is that it prevents disassembly of the mitotic spindle, which prevents spindle fibers from shortening. Which phase of mitosis would this directly affect? Why would this stop cell division overall and lead to cell death? LANDY సిగోలుకుం చగన 40 92800

0200 7 The anticancer drug paclitaxel (Taxol), derived from the Pacific Yew, has many effects on mitosis. One of its most powerful effects is that it prevents disassembly of the mitotic spindle, which prevents spindle fibers from shortening. Which phase of mitosis would this directly affect? Why would this stop cell division overall and lead to cell death? LANDY సిగోలుకుం చగన 40 92800

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter10: Cell Division And Mitosis

Section: Chapter Questions

Problem 1ITD: Biologists have long been interested in the effects of radiation on cells. In one experiment,...

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Biologists have long been interested in the effects of radiation on cells. In one experiment, researchers examined the effect of radium on mitosis of chick embryo cells growing in culture. A population of experimental cells was examined under the microscope for the number of cells in telophase (as a measure of mitosis occurring) before, during, and after exposure to radium. The results are shown in the Figure. What is the effect of radium exposure on mitosis? Source: R. G. Canti and M. Donaldson. 1926. The effect of radium on mitosis in vitro. Proceedings of the Royal Society of London, Series B, Containing Papers of a Biological Character 100:413419.
Chemotherapy drugs such as vincristine (derived from Madagascar periwinkle plants) and colchicine (derived from autumn crocus plants) disrupt mitosis by binding to tubulin (the subunit of microtubules) and interfering with microtubule assembly and disassembly. Exactly what mitotic structure is targeted by these drugs and what effect would that have on cell division?
Describe how the duplicated bacterial chromosomes are distributed into new daughter cells without the direction of the mitotic spindle.
The drug chloral hydrate prevents elongation of microtubules by preventing the addition of new subunits to the growing end. During which stage of mitosis would chloral hydrate be most harmful?
What experimental evidence indicates that cyclin B is re-quired for a cell to enter mitosis? What evidence indicates that cyclin B must be destroyed for a cell to exit mitosis?
Which of the following represents the correct order of the phases of mitosis?
A scientist studying a group of somatic cells notices that when the cell cycle is complete, half of the daughter cells have no chromosomes and the other half have 92 chromosomes. In what phase of mitosis did an error most likely occur? Explain.
What is the name of the cytoplasm division in the end of mitosis? What are the differences in this process between animal and plant cells?
QUESTION 37 What is the driving force to separate the spindle poles during Anaphase B of mitosis? A. Addition of microtubule subunits at the plus ends of the overlap microtubules. B. Loss of microtubule subunits from both ends of the astral microtubules. C. Addition of microtubules at the plus ends of the kinetochore microtubules. D. Loss of microtubule subunits from both ends of the kinetochore microtubules
What is the name of the structure that the microtubules bind to during mitosis?
What processes occur in the interphase cell before the onset of mitosis? Why is it incorrect to say that these cells are resting?
why During Mitosis, Sister ChromatidsSeparate and Two Daughter Nuclei Form?