1) Thalassaemia is a form of anaemia common in Mediterranean populations and resulting from a mutation to a single gene. It occurs in two forms. Individuals with thalassaemia major are homozygous and badly affected, whilst those with thalassaemia minor are heterozygous and only mildly affected. Individuals free of the disease are homozygous for the "normal" allele a) A man with thalassaemia minor marries a normal woman. With respect to thalassaemia, what types of children might they expect? b) Both father and mother in a particular family have thalassaemia minor. What is the chance that their baby will have i) be normal ii) have thalassaemia minor iii) have thalassaemia major?

1) Thalassaemia is a form of anaemia common in Mediterranean populations and resulting from a mutation to a single gene. It occurs in two forms. Individuals with thalassaemia major are homozygous and badly affected, whilst those with thalassaemia minor are heterozygous and only mildly affected. Individuals free of the disease are homozygous for the "normal" allele a) A man with thalassaemia minor marries a normal woman. With respect to thalassaemia, what types of children might they expect? b) Both father and mother in a particular family have thalassaemia minor. What is the chance that their baby will have i) be normal ii) have thalassaemia minor iii) have thalassaemia major?

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Description: 1) Thalassaemia is a form of anaemia common in Mediterranean populations and resulting from a mutation to asingle gene. It occurs in two forms. Individuals with thalassaemia major are homozygous and badly affected,whilst those with thalassaemia mino

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter10: From Proteins To Phenotypes

Section: Chapter Questions

Problem 11QP: a. If an individual who is homozygous for the mutation found in individual 2 and heterozygous for...

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