1) transposons are highly conserved DNA sequences that induce homologous recombination (true or false ) 2)Okazaki fragments are small pieces of RNA synthesized on the lagging strand during transcription (true or false) 3)homologous recombination is a eukaryotic chromatin exchange mechanism that is active during meiosis (true or false)

1) transposons are highly conserved DNA sequences that induce homologous recombination (true or false ) 2)Okazaki fragments are small pieces of RNA synthesized on the lagging strand during transcription (true or false) 3)homologous recombination is a eukaryotic chromatin exchange mechanism that is active during meiosis (true or false)

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations

Section: Chapter Questions

Problem 14QP: Variations in Chromosome NumberAneuploidy Describe the process of nondisjunction and explain when it...

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Domesticated sheep cells have a total of 54 chromosomes (versus 46 chromosomes in human cells). (a) How many separate DNA molecules are present in a sheep liver cell at the end of the G1 phase? (b) How many separate DNA molecules are present in the daughter cells after meiosis I in the ovary of the sheep? (c) How many separate DNA molecules are present in the daughter cells after meiosis II in the ovary of the sheep?
Could you please explain simple terms how does the base sequence contained in the telomeric regions of chromosomes differ from that found elsewhere in the chromosome?
In an electrophoretic gel across which is applied a powerful electrical alternating pulsed field, the DNA of the haploid fungus Neurospora crassa (n = 7) moves slowly but eventually forms seven bands, which represent DNA fractions that are of different sizes and hence have moved at different speeds. These bands are presumed to be the seven chromosomes. How would you show which band corresponds to which chromosome?
With detailed accounts of their various forms, explain any three of the following chromosomal aberrations: a) Deletions b) Duplications c) Translocations d)Inversion
Colchicine is a chemical mutagen that inhibits the spindle formation and prevents anaphase, which retains the cell’s single restitution nucleus (doubled chromosome number). Suppose that an onion (2n=16) is subjected to three consecutive rounds of colchicine treatment, what will be the resulting chromosome number of the treated onion?
Two phenotypically normal parents produce a phenotypically abnormal child in which chromosome 5 is missing part of its long arm but has a piece of chromosome 7 attached to it. The child also has one normal copy of chromosome 5 and two normal copies of chromosome 7. With regard to chromosomes 5 and 7, what do you think are the chromosomal compositions of the parents? Would it most likely be reciprocal translocation? It wouldn't be simple translocation because then the child would have the entirety of one chromosome and only some of the other, but in this case, there is only partial chromosome 5 and chromosome 7?
What is the specific base sequence found in human telomeres, and how does the base sequence contained in the telomeric regions of chromosomes differ from that found elsewhere in the chromosome? (Please indicate both the base sequence and the 5’/3’ polarity.)
Kuliev and Verlinsky (2004) state that there was a relatively high number of separation errors at meiosis I. In these cases the centromere underwent a premature division, occurring at meiosis I rather than meiosis II. Regarding chromosome 21, what would you expect to be the chromosome 21 complement in the secondary oocyte in which you saw a single chromatid (monad) for chromosome 21 in the first polar body? If this secondary oocyte was involved in fertilization, what would be the expected consequences?
During meiotic prophase in a eukaryotic cell, Spo11 initiates recombination by causing a double-strand break in DNA between Gene A and Gene B on one sister chromatid. Which of these events will occur prior to formation of a Holliday junction? A) A heteroduplex forms due to pairing of Gene A and Gene B. B) Resolvase cuts all four chromatids. C) Spo11 causes a double-strand break in a nonsister chromatid. D) Strand invasion causes one strand of the uncut chromatid to form a D loop. E) Branch migration lengthens the heteroduplex region to include Gene A and Gene
A pair of paralogous repeats, A and B, have 96% sequence similarity and therefore can promote non-allelic homologous recombination (NAHR). They exist in four possible arrangements in a genome, illustrated below as arrangements 1 – 4. What is the result of NAHR between repeats A and B in arrangement 1? A.Translocation between chromosomes 1 and 2 resulting in monocentric chromosomes B.Deletion or duplication of the region between A and B C.Translocation between chromosomes 1 and 2 resulting in acentric and dicentric chromosomes D.Inversion of the region between A and B
Consider the following two wild type chromosomes: AB•CDEFGH I•JKLMN What kind of rearrangement is observed in the mutated chromosomes below? AB•CLMN I•JKDEFGH A. non-reciprocal translocation B. tandem duplication C. reciprocal translocation D. displaced duplication E. deletion
A chromosome of genotype C D recombines with a homolog of genotype c d during meiosis when Spo11 produces a double-strand break between genes C and D. If anticrossover helicase disentangles the invading strand, the likely outcome would be A) two C D and two c d gametes. B) two C d and two c D gametes. C) one C D, one C d, one c D, and one c d gamete. D) four C D gametes. E) four c d gametes