Please explain. 1. On October 22, 2020, the FDA approved Veklury (remdesivir structure shown below)for use in adults and pediatric patients for the treatment of COVID-19 requiringhospitalization.A) Calculate the Kier-Hall electronegativity index (x) of atoms a-c.H₂C.H₂CCH3N PHd (CN)TAKE A TOURNH₂CENНО ОН 3a (N) =b (P)=c (0) =2345IVсVNPB) Using the information from A (above), denote the most polar bond in remdesivir by drawing its moleculardipole (use correct convention).C) Calculate the Kier-Hall electronegativity index (x) for functional group d. Show your calculations.VI VIIOFS CIBr1

The Kier Hall electronegativity index is calculated as: χ=column number-number of sigma bondsrow…

1. On October 22, 2020, the FDA approved Veklury (remdesivir structure shown below) for use in adults and pediatric patients for the treatment of COVID-19 requiring hospitalization. A) Calculate the Kier-Hall electronegativity index (x) of atoms a-c. H₂C H₂C CH3 N P d (CN) НО CEN OH NH₂ a (N) b (P) c (0) = 11 11 11 2245 IV C VNP C) Calculate the Kier-Hall electronegativity index (x) for functional group d. Show your calculations. VI VII F CI Br B) Using the information from A (above), denote the most polar bond in remdesivir by drawing its molecular dipole (use correct convention). 1

1. On October 22, 2020, the FDA approved Veklury (remdesivir structure shown below) for use in adults and pediatric patients for the treatment of COVID-19 requiring hospitalization. A) Calculate the Kier-Hall electronegativity index (x) of atoms a-c. H₂C H₂C CH3 N P d (CN) НО CEN OH NH₂ a (N) b (P) c (0) = 11 11 11 2245 IV C VNP C) Calculate the Kier-Hall electronegativity index (x) for functional group d. Show your calculations. VI VII F CI Br B) Using the information from A (above), denote the most polar bond in remdesivir by drawing its molecular dipole (use correct convention). 1

Chemistry & Chemical Reactivity

10th Edition

ISBN:9781337399074

Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel

Publisher:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel

Chapter23: Carbon: Not Just Another Element

Section: Chapter Questions

Problem 66PS

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