1. Put the following anions in order from most nucleophilic to least nucleophilic:      Br-   I-    F-    Cl-   2. Put the following leaving groups in order from best leaving group to worst leaving group:     Br   I   F   Cl

Q: 1. Draw the four major resonance contributor of the following molecule. Show all nucleophilic atoms…

A:

Q: 2. In the reaction below: a) b) Label the nucleophile (Nu) and the electrophile (E). Draw arrows on…

A: The reagents can be categorized into two types which are nucleophile and electrophile. Nucleophile…

Q: 5. For each reaction below, choose the reagent/s A) Br H20 A Br NaOH THF C) KOLBU CI KOTBU

A: The question is based on the concept of organic reactions.   we have to identify the Product formed…

Q: Rank these alkyl halides by their SN2 reaction rate. to Br CI Br Br A

A: A reaction rate relies on the concentration of nucleophile but not the reactant  is called as the…

Q: CN CN NH3 CH;OH Br Br OCH3 not formed

A: A nucleophile is an electron rich species, which can donate electron density in the form of lone…

Q: Chemistry Rank the following in order of increasing leaving group ability, putting the worst leaving…

A: Acid is substance which release hydrogen ions and base is substance which release hydroxyl ions when…

Q: LOH (RL NaOH (S) H2O This nucleophilic substitution occurs with rearrangement. Draw curved arrows to…

A: In this question, we will write the Nucleophilie reaction mechanism by using carved arrows.  You can…

Q: Rank the alkyl halides in order of increasing SN2 reactivity. Br Br Br Increasing S2 reactivity

A: According to guidelines i can answer only first question.

Q: Draw the alkyl bromide for reaction 2. Select Draw Rings More Erase H Br Reagents Carboxylic Acid…

A: Reactant

Q: What are the first and the second mechanistic step for this SN1 reaction? CH;SH Br A Carbocation…

A: Unimolecular nucleophilic substitution reaction (SN1): This reaction proceeds in two steps. The…

Q: Put the following leaving groups in order from best leaving group to worst leaving group: F Br I CI

A:

Q: CH, — 0— CH, + :0—н (b) СH, —0: + CH, —0— н CH; CH, -T ↑ I-Ö:

A:

Q: Consider the following SN2 reaction: Br + CN CN + Br acetone a. Draw a mechanism using curved…

A: Since we only answer up to 3 sub-parts, we’ll answer the first 3. Please resubmit the question and…

Q: Select the reagents that would promote the following reaction most efficiently. A NaOH 1. H2SO4…

A: Applying concept of organic synthesis and application of reagents.

Q: Draw an alkyl halide and choose the best reaction conditions that would undergo an SN2 reaction to…

A: In organic chemistry substitution reaction are those reaction where one functional group is…

Q: GS Q6: Show all missing reagents and products in the reaction sequence below. (E) (G), [H*] (F) -H20…

A:

Q: a) Draw the product(s) of the reactions below. Show the movement of electrons using curved arrows…

A:

Q: Do the reactions below proceed in good yield from left to right as shown? OH NaOH Na CI а) H2N' H2O…

A: Reaction occurs in good yields only when there is no competing reaction. Intramolecular reactions…

Q: Select the reagent that you would use to convert an alkene to an epoxide. mCPBA 03, then DMS…

A: The epoxide is a cyclic ether with a ring structure consisting of three atoms that somehow form an…

Q: 3. For each reaction below identify the electrophile and the nucleophile. Na + CH,CI CH,N3 a. NO,…

A: A Nucleophile Is A Reactant That Provides A Pair Of Electrons To Form A New Covalent Bond.  And  An…

Q: 10. Rank the species below in order of increasing nucleophilicity in polar aprotic solvents:…

A: A nucleophile is a chemical species that donates an electron pair to form a chemical bond in…

Q: Which one of the following is the best(faster reaction) base for the 2-methyl - 2-bromobutane E1…

A:

Q: Put the following leaving groups in order from best leaving group to worst leaving group: I…

A: Alkyl halide on treatment with base or nucleophile undergoes elimination or substitution reaction…

Q: (10 points) Complete the reaction scheme below. Show all reagents and intermediates. No reaction is…

A: Ans

Q: PART 2 - Resonance 1. Construct a reaction diagram including 2-methylpenta-1,3-diene and H- Br as…

A:

Q: acetone ỎMs H,N `NH2 j. acetone NaCI k. Br ether NaBr ÓMe 1.

A: As per rule only the first three can be answered.

Q: MARK 37. The primary product of the reaction below which uses excess HBr is which of the following…

A:

Q: Drawing Substitution and Elimination Products from a 2° Alkyl Halide Draw the products of the…

A: condition for substitution- good nucleophile good leaving group low temperature and low conc. of…

Q: Consider the following reaction. Which species is the nucleophile? :CN CN (1) ( II) ( III)

A: Nucleophile:  Nucleophiles are the electron-rich species which can donate an electron pair to form a…

Q: Can you match best nucleophile / conditions that will give a successful hydrolysis reaction for each…

A: For the given electrophile, acid chloride and acetic anhydride, water is used for the hydrolysis…

Q: Show the reagents for the conversion below: COOH HO NO2

A: The conversion given is,

Q: 15. Fill in the missing reagents for the 1st step. 16. Fill in the remaining missing reagents and…

A:

Q: Give the major product of the following reaction. 1) Hg(OAc)2, CH3OH ZON 2) NABH4, NAOH Br NO OMe Br…

A:

Q: Complete the mechanism for the electrophilic addition when the alkene is treated with water in acid.…

A: Introduction: An electrophilic addition reaction is the reaction in which an electrophile attack…

Q: Please complete the following synthesis. 1. Li ? Gilman Ragent 2. Cul Br Br Br Br B C D Br Br Br G F…

A:

Q: What is the nucleophile in the following reaction? SO IV OI Br I + Na CN II CN ! III 00 + Na Br IV

A:

Q: HCOO- > HO- > (CH3)2 Sort from best nucleophile to worst nucleophile

A:

Q: Choose the best option for the electrophile precursor to 2-hexanol. OH CH 30 Br nucleophile B O H…

A: During the formation of alcohol from alkyl halide there is water act as a nucleophilic while alkyl…

Q: The transformation above can be performed with some reagent or combination of the reagents listed…

A:

Q: 2. Rate these in order of reactivity to S,1 reactions. (1=most reactive) CI CI

A: Answer  The rate of the SN1 reaction depends on stability of carbocation. The stable carbocation…

Q: 5. Above each arrow, provide the missing reagents for each transformation. Above each step, indicate…

A:

Q: (1) BU Br 1- MeOH, 50 °C Draw the only product of the reaction. Draw Your Solution This product is…

A: In this question, we will draw the structure of product only and then show the type of reaction…

Q: H2O Н-ОН b. Br CH;COOH + CH;COOH Br CH3OH Br CH,0° Li + d. CH;OH • H-OCH3 ÓTs е.

A: Strong base  ------>  E2 Weak base --------> E1 Strong nucleophile  ------> SN2 Weak…

Q: 7. For each reaction below, determine whether the primary reaction is SN1, SN2, E1, or E2, and then…

A:

Q: For the Michael reaction shown below, which is the appropriate base to use for this reaction? base…

A: The reaction taking place is given below.

Q: Draw the alkyl bromide for reaction 3. Select Draw Rings More Erase H Br Reagents Carboxylic Acid…

A: Dimethyl malonate contains an active methylene group. It forms an enolate ion in the presence of a…

Q: 1c. What is the nucleophile in the following reaction? Br CH;COO Na L0OCCH3 + + NaBr 1d. What is the…

A:

Q: What is a major product of the reaction sequence shown in the box? Br2 ? -Br Pd(OAc)2, K2CO3 Bu4NBr,…

A:

Q: Draw the best reactant for the reaction below 1. LIAIH4 2. H20 NH2

A: This question is from organic chemistry. The first one is reduction reaction and second one is…

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.