1. Research on the Folsom Fruit Fly, D. folsomus, identified the pigment that is responsible for the black color in its body. Based on chemical analysis of the pigment, researchers hypothesized that three enzymes were involved in synthesizing the pigment from a colorless precursor compound. Furthermore, 3 genes were found to affect body color, and one dominant allele of each (p*, o* and a*) is required for the black phenotype. In mating experiments with mutant flies, the following recessive alleles (and their respective phenotypes) were also identified: p (pp confers a pink body phenotype) 0 (0o confers an orange body phenotype) a (aa confers an albino body phenotype) a) Draw a hypothetical, linear metabolic pathway, showing each reaction, enzyme and pigment or compound, which could account for the wild type and mutant phenotypes described above. If more than one possibility exists, draw only one and use it for 1b-d below as well. b) According to your hypothetical pathway, which genes are predicted to be epistatic to which other genes?

1. Research on the Folsom Fruit Fly, D. folsomus, identified the pigment that is responsible for the black color in its body. Based on chemical analysis of the pigment, researchers hypothesized that three enzymes were involved in synthesizing the pigment from a colorless precursor compound. Furthermore, 3 genes were found to affect body color, and one dominant allele of each (p, o and a*) is required for the black phenotype. In mating experiments with mutant flies, the following recessive alleles (and their respective phenotypes) were also identified: p (pp confers a pink body phenotype) 0 (0o confers an orange body phenotype) a (aa confers an albino body phenotype) a) Draw a hypothetical, linear metabolic pathway, showing each reaction, enzyme and pigment or compound, which could account for the wild type and mutant phenotypes described above. If more than one possibility exists, draw only one and use it for 1b-d below as well. b) According to your hypothetical pathway, which genes are predicted to be epistatic to which other genes?

Name: Please solve for both a) and b) 1.Research on the Folsom Fruit Fly, D.
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Description: Please solve for both a) and b) 1.Research on the Folsom Fruit Fly, D. folsomus, identified the pigment that is responsible for theblack color in its body. Based on chemical analysis of the pigment, researchers hypothesized that threeenzymes were inv

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter12: Mendel, Genes, And Inheritance

Section: Chapter Questions

Problem 9TYK: The ability of humans to taste the bitter chemical phenylthiocarbamide (PTC) is a genetic trait....

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4. Marfan syndrome is a genetic trait caused by in a dominant allele. The trait causes a weakening of the aorta that can be fatal. A teenager whose mother has the syndrome (but whose maternal grandfather was not affected), and whose father was unaffected, is concerend that she may have the trait. a. What is the phenotype of each of her parents? Genotype? b. What is the chance that the teenager has Marfan syndrome?
The ability of humans to taste the bitter chemical phenylthiocarbamide (PTC) is a genetic trait. People with at least one copy of the normal, dominant allele of the PTC gene can taste PTC; those who are homozygous for a mutant, recessive allele cannot taste it. Could two parents able to taste PTC have a nontaster child? Could nontaster parents have a child able to taste PTC? A pair of taster parents, both of whom had one parent able to taste PTC and one nontaster parent, are expecting their first child. What is the chance that the child will be able to taste PTC? Unable to taste PTC? Suppose the first child is a nontaster. What is the chance that their second child will also be unable to taste PTC?
Discuss Concepts Many human diseases are caused by recessive alleles that are not expressed in heterozygotes. Some people think that eugenicsthe selective breeding of humans to eliminate undesirable genetic traitsprovides a way for us to rid our populations of such harmful alleles. Explain why eugenics cannot eliminate such genetic traits from human populations.
1. In humans, widow’s peak (W) is dominant over having a straight hairline (w). If a homozygous man with a widow’s peak has a child with a woman with a straight hairline, what are the odds the child will have a widow’s peak? Show work. 2. Ellis-van Creveld syndrome is a recessive inherited condition that results in 6-fingered dwarfism. Two parents without this condition have with Ellis-van Creveld syndrome. What are the genotypes of the parents and offspring? What are the odds that the son will have a 6-fingered child if his partner is a woman who is heterozygous for the condition? Show work. 3. The gene for dangling earlobes is dominant over the gene for attached earlobes. A woman with attached earlobes has a child with a man with dangling earlobes whose mother had attached earlobes. What is the probability that this child will have attached lobes? Show work. 4. In humans, normal pigmentation is due to a dominant gene, while albinism is recessive. A normally pigmented man has a…
3. A couple just had a baby, who has type-O blood. Upon learning the baby’s blood type, the father becomesinfuriated and accuses the mother of cheating on him. The mother has type-A blood and the father has type-Bblood. Knowing that the allele for type-O is recessive, answer the following questions.a. What is the relationship between the IA, IB, and i alleles?b. Is the father right? Or is he falsely accusing the mother? Explain. Include the genotypes of the parentsand the genotypes of their potential children.
2. Anyone who inherits a single copy of the Huntington’s allele will get Huntington’s disease, if they live long enough. The age of onset of Huntington’s symptoms for those who inherit the disease allele can vary, starting in the patients’ 40s, 50s, or 60s. What is the genetic term for this variation in symptoms and in their time of appearance?
1. In Drosophila melanogaster (fruit fly) experiment, if we are going to cross male and female red-eyed fruit flies, we have the resulting offspring ratio of 50% red-eyed for female, 25 % for red-eyed male and 25% for white-eyed male. Females which are either homozygous or heterozygous for a trait still expressed eye redness whereas males can easily be affected. Why is this so? a. Females are the carriers of a gene for eye redness b. Y chromosome is responsible for red eyes in fruit flies, c. The gene for eye redness is an X-link dominant trait, d. Having a red-eyed trait is dominantly expressed by females
1. Discuss the basic structure and function of DNA as the genetic material. 2. Give the function of DNA in the transmission of trait from parent to offspring3. Discuss how Mendel formulated the Law of Inheritance in his pea plant experiment
2.In dogs, there is a hereditary deafness caused by a recessive allele, d. A kennel owner has a male dog that she wants to use for breeding purposes if possible. The dog can hear, but the owner is unsure of the genotype. She does a testcross (crosses it to a homozygous recessive dog), and two of the five offspring are deaf. This means that the male dog A.has the genotype DD B.has the genotype Dd C.is still of unknown genotype since there were offspring of both deaf and hearing phenotypes. D.has the genotype dd
1. Fruit Flies and Genetics Research: Imagine you are working in a genetics lab with the fruit fly Drosophila melanogaster, a model organism for genetics research. You want to determine whether a trait you have discovered in fruit flies is dominant or recessive.• Explain how you would design an experiment to answer this question.• Predict what types of outcomes are possible. Which would indicate that the trait is dominant? Which would indicate that it is recessive?2. Model Genetic Organisms: Why are fruit flies considered a model genetic organism? Would humans fit this description?
1. A sex-linked recessive allele rg causes a red-green colorblindness in humans. A normal woman whose father was colorblind marries a colorblind man. A. Of all the children of these parents (sex unspecified), what proportion can be expected to have normal color vision?
1. In fruit flies, the phenotype for eye color is determined by a certain locus. E indicates the dominant allele and eindicates the recessive allele. The cross between a male wild-type fruit fly and a female white-eyed fruit flyproduced the following offspring.Wild-typeMaleWild-typeFemaleWhite-eyedMaleWhite-eyedFemaleBrown-eyedFemaleF1 0 45 55 0 1The wild-type and white-eyed individuals from the F1 generation were then crossed to produce the followingoffspring.F2 23 31 22 24 0(a) Determine the genotypes of the original parents (P generation) and explain your reasoning. You may usePunnett squares to enhance your description, but the results from the Punnett squares must be discussed inyour answer.(b) Use a Chi-squared test on the F2 generation data to analyze your prediction of the parental genotypes. Showall your work and explain the importance of your final answer.(c) The brown-eyed female in the F1 generation resulted from a mutational change. Explain what a mutation is,and discuss…