1. The antibacterial activity of flavonoids was tested against the bacterial strain, Escherichia coli. The minimum inhibitory concentration at which 50% of the compounds were inhibited (MIC50) are presented in the table below for some of the compounds. Table 1: Antibacterial activity of flavonoids tested against E. coli Compound Kaempferol Quercetin Compound X Luteolin Tangeritin 5,6,7,4'- Tetramethoxyflavone Genistin Genistein b) 5,6,7,4'-Tetramethoxyflavone and tangeritin. c) Genistein and genistin. MIC50 (µg/mL) 25.50 35.76 36.72 67.25 137.10 156.34 1.2 Using structure-activity relationships, explain the differences in antibacterial activity between the following compounds: a) Quercetin and luteolin. Genistein and kaempferol. 238.94 320.88

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter16: Adult And Pediatric Dosages Based On Body Surface Area
Section: Chapter Questions
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1. The antibacterial activity of flavonoids was tested against the
bacterial strain, Escherichia coli. The minimum inhibitory
concentration at which 50% of the compounds were inhibited
(MIC50) are presented in the table below for some of the
compounds.
Table 1: Antibacterial activity of flavonoids tested against E.
coli
Compound
Kaempferol
Quercetin
Compound X
Luteolin
Tangeritin
5,6,7,4'-
Tetramethoxyflavone
Genistin
Genistein
MIC50 (µg/mL)
25.50
35.76
36.72
67.25
137.10
156.34
b)
5,6,7,4'-Tetramethoxyflavone and tangeritin.
c) Genistein and genistin.
d) Genistein and kaempferol.
238.94
320.88
1.2 Using structure-activity relationships, explain the differences
in antibacterial activity between the following compounds:
a) Quercetin and luteolin.
Transcribed Image Text:1. The antibacterial activity of flavonoids was tested against the bacterial strain, Escherichia coli. The minimum inhibitory concentration at which 50% of the compounds were inhibited (MIC50) are presented in the table below for some of the compounds. Table 1: Antibacterial activity of flavonoids tested against E. coli Compound Kaempferol Quercetin Compound X Luteolin Tangeritin 5,6,7,4'- Tetramethoxyflavone Genistin Genistein MIC50 (µg/mL) 25.50 35.76 36.72 67.25 137.10 156.34 b) 5,6,7,4'-Tetramethoxyflavone and tangeritin. c) Genistein and genistin. d) Genistein and kaempferol. 238.94 320.88 1.2 Using structure-activity relationships, explain the differences in antibacterial activity between the following compounds: a) Quercetin and luteolin.
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