1. Which of the following statements about CD4+ Th17 cells are true?

Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter45: Defenses Against Disease
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1. Which of the following statements about CD4+ Th17 cells are true?

i. Cannot form T effector memory (TEM) T cell populations

ii. Require the master transcription factor RORgammaT for their development

iii. Produce effector cytokines IL-17 and IL-22 which help recruit neutrophils and stimulate antimicrobial peptide production

iv. Do not require the transcription factor NFAT for IL-2 production downstream of TCR activation

v. Important for defense against intracellular bacterial infection only


a. i and iii
b. ii and v
c. ii and iii
d. ii, iii, iv
e. i, ii, and iv
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