10 20 30 40 Days of starvation Plasma concentration (mM) 4)
Chapter9: Parenteral Medication Labels And Dosage Calculation
Section: Chapter Questions
Problem 6.4P
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Transcribed Image Text:On the right is a diagram of plasma concentration of three metabolites: glucose, B-
hydroxybutyrate, and free fatty acid of an experimental animal over weeks of starvation.
4.
(a) Label the lines with the names of the three metabolites.
Yellow:
Red:
10
20
30
40
Blue:
Days of starvation
(b) What factor in the plasma binds to and transports free fatty acid
(c) Where was B-hydroxybutyrate produced? Why it is produced? What are the purposes of
producing it
(d) How B-hydroxybutyrate is used as fuel in extrahepatic cells? Write down the reactions, enzymes,
and cofactors (No need to elaborate on the TCA cycle).
(e) How many ATP molecules or equivalent are generated after complete oxidation of one molecule
of B-hydroxybutyrate? Show your calculations. Hint: You need to consider ATP consumption for
bypassed steps that may normally yield or consume AT
Plasma concentration (mM)
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